PMID- 27066903
OWN - NLM
STAT- MEDLINE
DCOM- 20161213
LR  - 20181113
IS  - 1749-8090 (Electronic)
IS  - 1749-8090 (Linking)
VI  - 11
IP  - 1
DP  - 2016 Apr 11
TI  - Aortic valve replacement in elderly with small aortic root and low body surface 
      area; the Perceval S valve and its impact in effective orifice area.
PG  - 54
LID - 10.1186/s13019-016-0438-7 [doi]
LID - 54
AB  - BACKGROUND: The aim of this study is to see how the sutureless, stentless, 
      Perceval S aortic valves behave when implanted in elderly patients with small 
      aortic root and the comparison with a second group of patients with similar 
      characteristics where a conventional stented bioprosthesis was implanted. This is 
      a prospective randomized institutional study. METHODS: Our material is composed 
      from 25 patients who underwent aortic valve replacement with sutureless 
      self-anchoring Perceval S valve implantation (LivaNova), compared with 25 
      patients with conventional stented biological prosthesis implanted (soprano 
      LivaNova group). The two groups of patients have similar demographic and medical 
      characteristics with severe aortic stenosis. The study was conducted from January 
      2012 to June 2014. Preoperative, intraoperative and postoperative parameters were 
      studied in order to investigate the utility of the Perceval S valves in this 
      group of patients. RESULTS: The Perceval S valve implantation seems to be an 
      interesting biological valve with good hemodynamic characteristics as compared 
      with the typical biological prosthesis providing shorter ischemia time (40 +/- 5.50 
      min vs 86 +/- 15.86 min; p < 0.001), shorter extracorporeal circulation time 
      (73.75 +/- 8.12 min vs 120.36 +/- 28.31 min p < 0.001), less operation time 
      (149.38 +/- 15.22 min vs 206.64 +/- 42.85 min; p < 0.001) and better postoperative 
      recovery. The postoperative gradients were 23.5 +/- 19.20 mmHg vs 24.5 +/- 19.90 mmHg 
      respectively. The postoperative effective orifice area in these two groups were 
      respectively 1.5 =/-0.19 cm(2) vs 1.1=/-0.5 cm(2) (p 0.002). Among the 25 
      patients of the Soprano stented valve, 3 (12 %) came back in 6 months with New 
      York Heart Association (NYHA) 3. The PPM of these patients was the cause of 
      readmission in the Hospital required diuresis and supplementary treatment. 
      CONCLUSIONS: Aortic valve replacement with Perceval aortic valves in geriatric 
      patients with comorbidities and small aortic annulus seems to be an alternative, 
      safe and "fast" intervention with excellent short and mid-term results which 
      provides a better effective orifice area.
FAU - Dedeilias, Panagiotis
AU  - Dedeilias P
AD  - Cardiothoracic and Vascular Surgery Department, "Evangelismos" General Hospital 
      of Athens, 45-47 Ipsilantou Street, Kolonaki, Athens, Greece.
FAU - Baikoussis, Nikolaos G
AU  - Baikoussis NG
AD  - Cardiothoracic and Vascular Surgery Department, "Evangelismos" General Hospital 
      of Athens, 45-47 Ipsilantou Street, Kolonaki, Athens, Greece. 
      nikolaos.baikoussis@gmail.com.
FAU - Prappa, Efstathia
AU  - Prappa E
AD  - Department of Cardiology, "Evangelismos" General Hospital of Athens, Athens, 
      Greece.
FAU - Asvestas, Dimitrios
AU  - Asvestas D
AD  - Department of Cardiology, "Evangelismos" General Hospital of Athens, Athens, 
      Greece.
FAU - Argiriou, Michalis
AU  - Argiriou M
AD  - Cardiothoracic and Vascular Surgery Department, "Evangelismos" General Hospital 
      of Athens, 45-47 Ipsilantou Street, Kolonaki, Athens, Greece.
FAU - Charitos, Christos
AU  - Charitos C
AD  - Cardiothoracic and Vascular Surgery Department, "Evangelismos" General Hospital 
      of Athens, 45-47 Ipsilantou Street, Kolonaki, Athens, Greece.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20160411
PL  - England
TA  - J Cardiothorac Surg
JT  - Journal of cardiothoracic surgery
JID - 101265113
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Aortic Valve/surgery
MH  - Aortic Valve Stenosis/*surgery
MH  - Bioprosthesis
MH  - Body Surface Area
MH  - Female
MH  - *Heart Valve Prosthesis
MH  - Heart Valve Prosthesis Implantation/*instrumentation/methods
MH  - Hemodynamics
MH  - Humans
MH  - Male
MH  - Operative Time
MH  - Prospective Studies
MH  - Prosthesis Design
MH  - Stents
MH  - Sutureless Surgical Procedures/instrumentation/methods
PMC - PMC4827171
OTO - NOTNLM
OT  - Aortic valve
OT  - Aortic valve stenosis
OT  - Heart valve surgery
OT  - Perceval S
OT  - Self-expanding valve
OT  - Stentless aortic valve
OT  - Sutureless valve
EDAT- 2016/04/14 06:00
MHDA- 2016/12/15 06:00
PMCR- 2016/04/11
CRDT- 2016/04/13 06:00
PHST- 2015/08/18 00:00 [received]
PHST- 2016/04/03 00:00 [accepted]
PHST- 2016/04/13 06:00 [entrez]
PHST- 2016/04/14 06:00 [pubmed]
PHST- 2016/12/15 06:00 [medline]
PHST- 2016/04/11 00:00 [pmc-release]
AID - 10.1186/s13019-016-0438-7 [pii]
AID - 438 [pii]
AID - 10.1186/s13019-016-0438-7 [doi]
PST - epublish
SO  - J Cardiothorac Surg. 2016 Apr 11;11(1):54. doi: 10.1186/s13019-016-0438-7.