PMID- 27067153
OWN - NLM
STAT- MEDLINE
DCOM- 20170123
LR  - 20170123
IS  - 1943-572X (Electronic)
IS  - 0003-4894 (Linking)
VI  - 125
IP  - 8
DP  - 2016 Aug
TI  - Identification and Prevalence of Allergic, Nonallergic, and Local Allergic 
      Rhinitis Patients in Western Area, Saudi Arabia.
PG  - 634-43
LID - 10.1177/0003489416642785 [doi]
AB  - OBJECTIVES: To evaluate the diagnostic yield of skin prick test (SPT) and serum 
      total immunoglobulin E (IgE) antibodies level in patients with allergic rhinitis 
      (AR) and the role of nasal provocation test (NPT) for the determination of local 
      allergic rhinitis (LAR) in patients with nonallergic rhinitis (NAR). METHODOLOGY: 
      This multi-center study included 1230 patients with clinical manifestations for 
      >/=2 years. Patients were classified according to the Allergic Rhinitis and Its 
      Impact on Asthma (ARIA) and scored according to the quantitative Score for 
      Allergic Rhinitis (SFAR). The SPT and total IgE antibody levels were done for all 
      patients. Patients gave negative SPT underwent NPT, and its result was 
      interpreted using Lebel Symptom Score Scale. RESULTS: The SPT was positive in 
      77.8% of patients, mostly for grass pollen and dust mites. All patients were 
      sensitive to multiple allergens. Median serum IgE antibody level for total study 
      population was 162 IU/ml. Forty-two patients (3.4%) with negative SPT showed a 
      weak response to NPT, while 231 patients (18.7%) with negative SPT had a high 
      response to NPT and were considered to have LAR. CONCLUSION: The SPT could 
      discriminate between AR and NAR patients. The NPT could identify LAR in 84.6% of 
      patients with rhinitis among those considered as NAR.
CI  - (c) The Author(s) 2016.
FAU - Badran, Hatem S
AU  - Badran HS
AD  - Department of Otorhinolaryngology, Faculty of Medicine, Cairo University, Egypt.
FAU - Hussein, Ahmed
AU  - Hussein A
AD  - Department of Otorhinolaryngology, Faculty of Medicine, Cairo University, Egypt 
      Asilyahmed@yahoo.com.
FAU - Salah, Mohamad
AU  - Salah M
AD  - Department of Otorhinolaryngology, Faculty of Medicine, Zagazig University, 
      Egypt.
FAU - Lotfi, Wassim T
AU  - Lotfi WT
AD  - Department of Otorhinolaryngology, Faculty of Medicine, Fayoum University, Egypt.
LA  - eng
PT  - Journal Article
DEP - 20160411
PL  - United States
TA  - Ann Otol Rhinol Laryngol
JT  - The Annals of otology, rhinology, and laryngology
JID - 0407300
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adult
MH  - Animals
MH  - Female
MH  - Humans
MH  - Immunoglobulin E/immunology
MH  - Male
MH  - Middle Aged
MH  - Nasal Provocation Tests
MH  - Poaceae/immunology
MH  - Prospective Studies
MH  - Pyroglyphidae/immunology
MH  - Rhinitis/diagnosis/epidemiology/immunology
MH  - Rhinitis, Allergic/diagnosis/*epidemiology/immunology
MH  - Rhinitis, Allergic, Seasonal/*epidemiology/immunology
MH  - Saudi Arabia/epidemiology
MH  - Sensitivity and Specificity
MH  - Skin Tests
MH  - Young Adult
OTO - NOTNLM
OT  - allergic rhinitis
OT  - local allergic rhinitis
OT  - nasal provocation test
OT  - nonallergic rhinitis
OT  - skin pricking test
EDAT- 2016/04/14 06:00
MHDA- 2017/01/24 06:00
CRDT- 2016/04/13 06:00
PHST- 2016/04/13 06:00 [entrez]
PHST- 2016/04/14 06:00 [pubmed]
PHST- 2017/01/24 06:00 [medline]
AID - 0003489416642785 [pii]
AID - 10.1177/0003489416642785 [doi]
PST - ppublish
SO  - Ann Otol Rhinol Laryngol. 2016 Aug;125(8):634-43. doi: 10.1177/0003489416642785. 
      Epub 2016 Apr 11.