PMID- 27069674 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20160412 LR - 20201001 IS - 2090-004X (Print) IS - 2090-0058 (Electronic) IS - 2090-004X (Linking) VI - 2016 DP - 2016 TI - Peripapillary Retinoschisis in Glaucoma Patients. PG - 1612720 LID - 10.1155/2016/1612720 [doi] LID - 1612720 AB - Purpose. To investigate peripapillary retinoschisis and its effect on retinal nerve fiber layer (RNFL) thickness measurements by using spectral-domain optical coherence tomography (SD-OCT) in glaucomatous eyes. Methods. Circumpapillary RNFL (cpRNFL) B-scan images of 940 glaucoma patients (Group 1) and 801 glaucoma-suspect patients (Group 2) obtained by SD-OCT were reviewed. The structural and clinical characteristics of the retinoschisis were investigated. The RNFL thickness measurements taken at the time of retinoschisis diagnosis and at the follow-up visits were also compared. Results. Twenty-nine retinoschisis areas were found in 26 of the 940 glaucoma patients (3.1%) in Group 1 and seven areas were found in 801 patients (0.87%) in Group 2. In glaucomatous eyes, the retinoschisis was attached to the optic disc and overlapped with the RNFL defect. At the time of retinoschisis, the RNFL thickness was statistically greater in the inferior temporal quadrant when compared with the follow-up scans (p < 0.001). No macular involvement or retinal detachment was observed. Conclusion. The present study investigated 33 peripapillary retinoschisis patients. Increase in RNFL thickness measurements was observed at the time of retinoschisis. It is important to examine the cpRNFL B-scan images of glaucoma patients so that the RNFL thickness is not overestimated. FAU - Bayraktar, Serife AU - Bayraktar S AD - Istanbul Faculty of Medicine, Department of Ophthalmology, Istanbul University, 34093 Istanbul, Turkey. FAU - Cebeci, Zafer AU - Cebeci Z AD - Istanbul Faculty of Medicine, Department of Ophthalmology, Istanbul University, 34093 Istanbul, Turkey. FAU - Kabaalioglu, Melis AU - Kabaalioglu M AD - Istanbul Faculty of Medicine, Department of Ophthalmology, Istanbul University, 34093 Istanbul, Turkey. FAU - Ciloglu, Serife AU - Ciloglu S AD - Istanbul Faculty of Medicine, Department of Ophthalmology, Istanbul University, 34093 Istanbul, Turkey. FAU - Kir, Nur AU - Kir N AD - Istanbul Faculty of Medicine, Department of Ophthalmology, Istanbul University, 34093 Istanbul, Turkey. FAU - Izgi, Belgin AU - Izgi B AD - Istanbul Faculty of Medicine, Department of Ophthalmology, Istanbul University, 34093 Istanbul, Turkey. LA - eng PT - Journal Article DEP - 20160316 PL - United States TA - J Ophthalmol JT - Journal of ophthalmology JID - 101524199 PMC - PMC4812388 EDAT- 2016/04/14 06:00 MHDA- 2016/04/14 06:01 PMCR- 2016/03/16 CRDT- 2016/04/13 06:00 PHST- 2016/01/18 00:00 [received] PHST- 2016/02/16 00:00 [revised] PHST- 2016/02/21 00:00 [accepted] PHST- 2016/04/13 06:00 [entrez] PHST- 2016/04/14 06:00 [pubmed] PHST- 2016/04/14 06:01 [medline] PHST- 2016/03/16 00:00 [pmc-release] AID - 10.1155/2016/1612720 [doi] PST - ppublish SO - J Ophthalmol. 2016;2016:1612720. doi: 10.1155/2016/1612720. Epub 2016 Mar 16.