PMID- 27069681
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160412
LR  - 20220317
IS  - 2090-1348 (Print)
IS  - 2090-1356 (Electronic)
IS  - 2090-1348 (Linking)
VI  - 2016
DP  - 2016
TI  - Relation of Perceived Stigma to Adverse Events of Medications in Patients with 
      Epilepsy.
PG  - 5362806
LID - 10.1155/2016/5362806 [doi]
LID - 5362806
AB  - Purpose. We aimed to assess the influence of adverse events (AEs) of 
      antiepileptic drugs (AEDs) on perceived stigma of Bulgarian patients with 
      epilepsy. Methods. Our study was based on questionnaires (Liverpool Adverse 
      Events Profile (LAEP) and stigma scale), information from medical documentation, 
      and an interview on clinical factors of 153 consecutive patients with epilepsy. 
      Results. Perceived stigma was observed in 64.71% of the study participants. There 
      was a significant association between perceived stigma and the total LAEP score 
      (p < 0.05, F = 13.71). Patients who reported AEs had an increased risk of 
      perceiving stigma compared to those who did not experience AEs. A significant 
      correlation between perceived stigma and the presence of neurological and 
      psychiatric AEs (p < 0.001, r = +0.60) and a mild correlation between perceived 
      stigma and the presence of nonneurological AEs (p < 0.01, r = +0.20) were 
      verified. In a multivariate regression analysis the only predictors of perceived 
      stigma were AED polytherapy and the presence of neurological and psychiatric AEs. 
      Conclusions. AEs of AEDs in patients with epilepsy significantly correlate with 
      perceived stigma. Our study results will be useful in the campaign to overcome 
      stigma predictors.
FAU - Viteva, Ekaterina
AU  - Viteva E
AD  - Department of Neurology, University of Medicine, 15A Vassil Aprilov Street, 4002 
      Plovdiv, Bulgaria.
LA  - eng
PT  - Journal Article
DEP - 20160316
PL  - United States
TA  - Epilepsy Res Treat
JT  - Epilepsy research and treatment
JID - 101576602
PMC - PMC4812353
EDAT- 2016/04/14 06:00
MHDA- 2016/04/14 06:01
PMCR- 2016/03/16
CRDT- 2016/04/13 06:00
PHST- 2015/09/24 00:00 [received]
PHST- 2016/02/02 00:00 [revised]
PHST- 2016/02/21 00:00 [accepted]
PHST- 2016/04/13 06:00 [entrez]
PHST- 2016/04/14 06:00 [pubmed]
PHST- 2016/04/14 06:01 [medline]
PHST- 2016/03/16 00:00 [pmc-release]
AID - 10.1155/2016/5362806 [doi]
PST - ppublish
SO  - Epilepsy Res Treat. 2016;2016:5362806. doi: 10.1155/2016/5362806. Epub 2016 Mar 
      16.