PMID- 27078246
OWN - NLM
STAT- MEDLINE
DCOM- 20160829
LR  - 20170404
IS  - 1439-4413 (Electronic)
IS  - 0012-0472 (Linking)
VI  - 141
IP  - 8
DP  - 2016 Apr
TI  - [Acute gastrointestinal bleeding].
PG  - 561-8; quiz 569-70
LID - 10.1055/s-0042-101721 [doi]
AB  - Acute gastrointestinal bleeding is a common major emergency (Internal medical or 
      gastroenterological or medical), approximately 85 % of which occur in the upper 
      GI tract. It is estimated that about a half of upper GI bleeds are caused by 
      peptic ulcers. Upper GI bleeds are associated with more severe bleeding and 
      poorer outcomes when compared to middle or lower GI bleeds. Prognostic 
      determinants include bleeding intensity, patient age, comorbid conditions and the 
      concomitant use of anticoagulants. A focused medical history can offer insight 
      into the bleeding intensity, location and potential cause (along with early risk 
      stratification). Initial measures should focus on rapid assessment and 
      resuscitation of unstable patients. The oesophagogastroduodenoscopy (OGD) is the 
      gold standard method for localizing the source of bleeding and for interventional 
      therapy. Bleeding as a result of peptic ulcers is treated endoscopically with 
      mechanical and / or thermal techniques in combination with proton pump inhibitor 
      (PPI) therapy. When variceal bleeding is suspected, pre-interventional use of 
      vasopressin analogues and antibiotic therapies are recommended. Endoscopically, 
      the first line treatment of esophageal varices is endoscopic ligature therapy, 
      whereas that for gastric varices is the use of Histoacryl injection 
      sclerotherapy. When persistent and continued massive hemorrhage occurs in a 
      patient with known or suspected aortic disease the possibility of an 
      aorto-enteric fistula must be considered.
CI  - (c) Georg Thieme Verlag KG Stuttgart . New York.
FAU - Baumbach, Robert
AU  - Baumbach R
FAU - Faiss, Siegbert
AU  - Faiss S
FAU - Cordruwisch, Wolfgang
AU  - Cordruwisch W
FAU - Schrader, Carsten
AU  - Schrader C
LA  - ger
PT  - English Abstract
PT  - Journal Article
TT  - Akute obere gastrointestinale Blutung.
DEP - 20160414
PL  - Germany
TA  - Dtsch Med Wochenschr
JT  - Deutsche medizinische Wochenschrift (1946)
JID - 0006723
SB  - IM
EIN - Dtsch Med Wochenschr. 2016 Jul;141(13):922. PMID: 27359306
MH  - Acute Disease
MH  - Female
MH  - *Gastrointestinal Hemorrhage
MH  - Humans
MH  - Middle Aged
EDAT- 2016/04/15 06:00
MHDA- 2016/08/30 06:00
CRDT- 2016/04/15 06:00
PHST- 2016/04/15 06:00 [entrez]
PHST- 2016/04/15 06:00 [pubmed]
PHST- 2016/08/30 06:00 [medline]
AID - 10.1055/s-0042-101721 [doi]
PST - ppublish
SO  - Dtsch Med Wochenschr. 2016 Apr;141(8):561-8; quiz 569-70. doi: 
      10.1055/s-0042-101721. Epub 2016 Apr 14.