PMID- 27087951
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160418
LR  - 20181113
IS  - 2050-6406 (Print)
IS  - 2050-6414 (Electronic)
IS  - 2050-6406 (Linking)
VI  - 4
IP  - 2
DP  - 2016 Apr
TI  - Prevalence of severe esophagitis in Spain. Results of the PRESS study (Prevalence 
      and Risk factors for Esophagitis in Spain: A cross-sectional study).
PG  - 229-35
LID - 10.1177/2050640615595916 [doi]
AB  - BACKGROUND: *N.P. and M.P. contributed equally to this study.The current 
      prevalence of esophagitis in southern Europe is unknown. In addition, the risk 
      factors for reflux esophagitis are not fully understood. OBJECTIVE: The objective 
      of this article is to assess the prevalence and risk factors for esophagitis in 
      Spain. METHODS: A prospective, observational, cross-sectional, multicenter study 
      (PRESS study) was conducted among 31 gastrointestinal endoscopy units throughout 
      Spain. A total of 1361 patients undergoing upper gastrointestinal endoscopy were 
      enrolled. Sociodemographic, clinical and treatment data were recorded. RESULTS: A 
      total of 95% of patients were Caucasian and 52% were male (mean age: 53 +/- 17 
      years). The most frequent symptoms prompting endoscopy were heartburn (40%), 
      regurgitation (26%) and dysphagia (15%). Fifty-four percent of patients 
      undergoing endoscopy were receiving proton pump inhibitor (PPI) treatment. 
      Esophagitis (mainly mild-moderate) was present in 154 (12.4%) patients. The 
      severe form was recorded in only 11 (0.8%) patients. Multivariate analysis 
      results indicated that the likelihood of esophagitis was higher in men 
      (OR = 1.91, 95% CI = 1.31-2.78), in patients with high GERD-Q scores (OR = 1.256, 
      95% CI = 1.176-1.343), weight increase (OR = 1.014, 95% CI = 1.003-1.025) and 
      high alcohol consumption (OR = 2.49, 95% CI = 1.16-5.36). CONCLUSION: Severe 
      esophagitis is a rare finding in the Spanish population. Male gender, high GERD-Q 
      score, weight increase and high alcohol consumption are main risk factors for its 
      appearance.
FAU - Pique, Nuria
AU  - Pique N
AD  - Department of Microbiology and Parasitology, Pharmacy Faculty, Universitat de 
      Barcelona, Spain.
FAU - Ponce, Marta
AU  - Ponce M
AD  - Department of Gastroenterology, Hospital Universitario La Fe, Valencia, Spain.
FAU - Garrigues, Vicente
AU  - Garrigues V
AD  - Department of Gastroenterology, Hospital Universitario La Fe, Valencia, Spain.
FAU - Rodrigo, Luis
AU  - Rodrigo L
AD  - Digestive Tract Department, Hospital Central de Asturias, Oviedo, Spain.
FAU - Calvo, Felix
AU  - Calvo F
AD  - Department of Gastroenterology, Complejo Hospitalario Universitario de Albacete, 
      Albacete, Spain.
FAU - de Argila, Carlos Martin
AU  - de Argila CM
AD  - Department of Gastroenterology, Hospital Universitario Ramon y Cajal, Madrid, 
      Spain.
FAU - Borda, Fernando
AU  - Borda F
AD  - Service of Digestive Tract, Hospital de Navarra, Pamplona, Spain.
FAU - Naranjo, Antonio
AU  - Naranjo A
AD  - Gastroenterology and Hepatology Department, University Hospital Reina Sofia, 
      Cordoba, Spain.
FAU - Alcedo, Javier
AU  - Alcedo J
AD  - Gastroenterology and Hepatology, Hospital San Jorge, Huesca, Spain.
FAU - Jose Soria, Maria
AU  - Jose Soria M
AD  - Department of Digestive Tract, Hospital Universitario Puerta del Mar, Cadiz, 
      Spain.
FAU - Rey, Enrique
AU  - Rey E
AD  - Department of Digestive Tract, Hospital Clinico Universitario San Carlos, Madrid, 
      Spain.
FAU - Bujanda, Luis
AU  - Bujanda L
AD  - Department of Gastroenterology Hospital de Donostia, San Sebastian, Spain; 
      Instituto Biodonostia (Universidad del Pais Vasco UPV/EHU), Spain; Centro de 
      Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas (CIBERehd), 
      Madrid, Spain.
FAU - Gisbert, Javier P
AU  - Gisbert JP
AD  - Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas 
      (CIBERehd), Madrid, Spain; Hospital Universitario de la Princesa, Instituto de 
      Investigacion Sanitaria Princesa (IIS-IP), Madrid, Spain.
FAU - Suarez, David
AU  - Suarez D
AD  - Unitat d'Epidemiologia i Avaluacio-Fundacio Parc Tauli, Hospital de Sabadell, 
      Institut Universitari Parc Tauli, Universitat Autonoma de Barcelona, Sabadell, 
      Spain.
FAU - Calvet, Xavier
AU  - Calvet X
AD  - Hospital Universitario de la Princesa, Instituto de Investigacion Sanitaria 
      Princesa (IIS-IP), Madrid, Spain; Department of Gastroenterology, Corporacio 
      Sanitaria Universitaria Parc Tauli, Sabadell (Barcelona), Spain; Departament de 
      Medicina, Universitat Autonoma de Barcelona, Barcelona, Spain.
FAU - Ponce, Julio
AU  - Ponce J
AD  - Department of Gastroenterology, Hospital Universitario La Fe, Valencia, Spain.
CN  - PRESS Study Group
LA  - eng
PT  - Journal Article
DEP - 20150724
PL  - England
TA  - United European Gastroenterol J
JT  - United European gastroenterology journal
JID - 101606807
PMC - PMC4804364
OTO - NOTNLM
OT  - Barrett's esophagus
OT  - Endoscopy
OT  - gastro-esophageal reflux disease (GERD)
OT  - gastrointestinal symptoms
OT  - hiatal hernia
OT  - nonsteroidal anti-inflammatory drugs (NSAID)
OT  - questionnaires
OT  - severe esophagitis
EDAT- 2016/04/19 06:00
MHDA- 2016/04/19 06:01
PMCR- 2016/04/01
CRDT- 2016/04/19 06:00
PHST- 2015/04/16 00:00 [received]
PHST- 2015/06/21 00:00 [accepted]
PHST- 2016/04/19 06:00 [entrez]
PHST- 2016/04/19 06:00 [pubmed]
PHST- 2016/04/19 06:01 [medline]
PHST- 2016/04/01 00:00 [pmc-release]
AID - 10.1177_2050640615595916 [pii]
AID - 10.1177/2050640615595916 [doi]
PST - ppublish
SO  - United European Gastroenterol J. 2016 Apr;4(2):229-35. doi: 
      10.1177/2050640615595916. Epub 2015 Jul 24.