PMID- 27095068 OWN - NLM STAT- MEDLINE DCOM- 20180102 LR - 20180102 IS - 2151-0903 (Electronic) IS - 0886-9634 (Linking) VI - 35 IP - 1 DP - 2017 Jan TI - Cephalometric risk factors associated with myocardial infarction in patients suffering from obstructive sleep apnea: A pilot case-control study. PG - 15-18 LID - 10.1080/08869634.2016.1169615 [doi] AB - INTRODUCTION: Obstructive sleep apnea (OSA) and its craniofacial anatomic risk factors might play a role in several cardiovascular diseases, including myocardial infarction (MI). However, there are no data about cephalometric findings among OSA patients with MI. METHODS: In this pilot case-control study, about 2000 individuals referred to the sleep center were evaluated according to apnea - hypopnea index (AHI) and other inclusion criteria. Included were 62 OSA male patients (AHI > 10), of whom 6 had an MI history. In both control (n = 56) and MI groups (n = 6), 18 cephalometric parameters were traced. Data were analyzed using independent samples t-test. RESULTS: Compared with control OSA patients, OSA patients with MI showed a significantly larger tongue length (p = 0.015). The other cephalometric variables were not significantly different between the two groups. CONCLUSION: An elongated tongue might be considered a risk factor for MI in OSA patients. The role of other variables remains inconclusive and open to investigation with larger samples (determined based on pilot studies such as this report) collected in longitudinal fashion. FAU - Davoudmanesh, Zeinab AU - Davoudmanesh Z AD - a Craniomaxillofacial Research Center, Shariati Hospital , Tehran University of Medical Sciences , Tehran , Iran. AD - b Craniomaxillofacial Surgery Research Center , Dental Branch, Islamic Azad University , Tehran , Iran. FAU - Bayat, Mohamad AU - Bayat M AD - a Craniomaxillofacial Research Center, Shariati Hospital , Tehran University of Medical Sciences , Tehran , Iran. AD - c Dental Faculty, Department of Oral and Maxillofacial Surgery , Tehran University of Medical Sciences , Tehran , Iran. FAU - Abbasi, Mohsen AU - Abbasi M AD - a Craniomaxillofacial Research Center, Shariati Hospital , Tehran University of Medical Sciences , Tehran , Iran. AD - c Dental Faculty, Department of Oral and Maxillofacial Surgery , Tehran University of Medical Sciences , Tehran , Iran. FAU - Rakhshan, Vahid AU - Rakhshan V AD - d Iranian Tissue Engineering and Graft Research Center , Tehran University of Medical Sciences , Tehran , Iran. AD - e Department of Dental Anatomy and Morphology , Dental Branch, Islamic Azad University , Tehran , Iran. FAU - Shariati, Mahsa AU - Shariati M AD - a Craniomaxillofacial Research Center, Shariati Hospital , Tehran University of Medical Sciences , Tehran , Iran. LA - eng PT - Journal Article DEP - 20160420 PL - England TA - Cranio JT - Cranio : the journal of craniomandibular practice JID - 8609491 MH - Adult MH - Aged MH - Body Mass Index MH - Case-Control Studies MH - Cephalometry/*methods MH - Facial Bones/pathology MH - Female MH - Humans MH - Male MH - Middle Aged MH - Myocardial Infarction/*complications/pathology MH - Orthodontics MH - Risk Factors MH - Sleep MH - Sleep Apnea, Obstructive/*complications/pathology MH - Statistics, Nonparametric MH - Surgery, Oral MH - Tongue/pathology OTO - NOTNLM OT - Cephalometric analysis OT - Maxillofacial surgery OT - Myocardial infarction OT - Obstructive sleep apnea OT - Orthodontics EDAT- 2016/04/21 06:00 MHDA- 2018/01/03 06:00 CRDT- 2016/04/21 06:00 PHST- 2016/04/21 06:00 [pubmed] PHST- 2018/01/03 06:00 [medline] PHST- 2016/04/21 06:00 [entrez] AID - 10.1080/08869634.2016.1169615 [doi] PST - ppublish SO - Cranio. 2017 Jan;35(1):15-18. doi: 10.1080/08869634.2016.1169615. Epub 2016 Apr 20.