PMID- 27096633
OWN - NLM
STAT- MEDLINE
DCOM- 20180208
LR  - 20180208
IS  - 1879-1026 (Electronic)
IS  - 0048-9697 (Linking)
VI  - 562
DP  - 2016 Aug 15
TI  - Influence of parasitism in dogs on their serum levels of persistent 
      organochlorine compounds and polycyclic aromatic hydrocarbons.
PG  - 128-135
LID - S0048-9697(16)30627-1 [pii]
LID - 10.1016/j.scitotenv.2016.03.204 [doi]
AB  - Persistent organochlorine pollutants (POPs) are toxic chemicals, which accumulate 
      in humans and animals, as only few species have the capability of eliminating 
      them. However, some authors have pointed to the possibility that certain species 
      of invertebrates (i.e. nematodes) could metabolize this type of compounds. As 
      certain species of nematodes act as parasites of vertebrates, this research was 
      designed to explore the influence of some of the most common parasites of the 
      dogs in their serum levels of 56 common POPs. The study included three groups of 
      dogs (n=64), which were prospectively recruited in the island of Gran Canaria 
      (Canary Islands, Spain): a) control animals, non-parasitized (serologically 
      tested negative, n=24); b) dogs tested positive for intestinal parasites and 
      negative for other parasites (n=24); and c) dogs tested positive for heartworm 
      disease (Dirofilaria immitis) and negative for other parasites (n=16). The 
      presence of Dirofilaria immitis was strongly associated with lower serum levels 
      of a wide range of pollutant in their hosts (PCB congeners 28, 52, 118, 138, 153, 
      and 180; hexachlorobenzene, lindane, aldrin, dieldrin, anthracene and pyrene). We 
      also found an inverse association between the hosts' serum levels of PCBs and 
      intestinal parasites. We did not find any association with DDT or its 
      metabolites, but this might be explained by the recently suggested ability of 
      dogs for the efficient metabolization of these compounds. According to the 
      results of this study certain forms of parasitism would reduce the 
      bioavailability of the major classes of POPs in dogs. However, further studies 
      are needed to elucidate whether this phenomenon is due to a competence between 
      parasites and hosts or could respond to a possible capability of parasitic 
      nematodes for the metabolization of these POPs.
CI  - Copyright (c) 2016 Elsevier B.V. All rights reserved.
FAU - Henriquez-Hernandez, Luis A
AU  - Henriquez-Hernandez LA
AD  - Toxicology Unit, Research Institute of Biomedical and Health Sciences (IUIBS), 
      University of Las Palmas de Gran Canaria, Cabrera Felipe s/n, 35016 Las Palmas de 
      Gran Canaria, Spain; Spanish Biomedical Research Centre in Physiopathology of 
      Obesity and Nutrition (CIBERObn), Paseo Blas Cabrera Felipe s/n, 35016 Las Palmas 
      de Gran Canaria, Spain.
FAU - Carreton, Elena
AU  - Carreton E
AD  - Internal Medicine Service, Faculty of Veterinary Medicine, Research Institute of 
      Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria, 
      Paseo Blas Cabrera Felipe s/n, 35016 Las Palmas de Gran Canaria, Spain.
FAU - Camacho, Maria
AU  - Camacho M
AD  - Toxicology Unit, Research Institute of Biomedical and Health Sciences (IUIBS), 
      University of Las Palmas de Gran Canaria, Cabrera Felipe s/n, 35016 Las Palmas de 
      Gran Canaria, Spain; Spanish Biomedical Research Centre in Physiopathology of 
      Obesity and Nutrition (CIBERObn), Paseo Blas Cabrera Felipe s/n, 35016 Las Palmas 
      de Gran Canaria, Spain.
FAU - Montoya-Alonso, Jose Alberto
AU  - Montoya-Alonso JA
AD  - Internal Medicine Service, Faculty of Veterinary Medicine, Research Institute of 
      Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria, 
      Paseo Blas Cabrera Felipe s/n, 35016 Las Palmas de Gran Canaria, Spain.
FAU - Boada, Luis D
AU  - Boada LD
AD  - Toxicology Unit, Research Institute of Biomedical and Health Sciences (IUIBS), 
      University of Las Palmas de Gran Canaria, Cabrera Felipe s/n, 35016 Las Palmas de 
      Gran Canaria, Spain; Spanish Biomedical Research Centre in Physiopathology of 
      Obesity and Nutrition (CIBERObn), Paseo Blas Cabrera Felipe s/n, 35016 Las Palmas 
      de Gran Canaria, Spain.
FAU - Valeron, Pilar F
AU  - Valeron PF
AD  - Toxicology Unit, Research Institute of Biomedical and Health Sciences (IUIBS), 
      University of Las Palmas de Gran Canaria, Cabrera Felipe s/n, 35016 Las Palmas de 
      Gran Canaria, Spain; Spanish Biomedical Research Centre in Physiopathology of 
      Obesity and Nutrition (CIBERObn), Paseo Blas Cabrera Felipe s/n, 35016 Las Palmas 
      de Gran Canaria, Spain.
FAU - Cordon, Yaiza Falcon
AU  - Cordon YF
AD  - Internal Medicine Service, Faculty of Veterinary Medicine, Research Institute of 
      Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria, 
      Paseo Blas Cabrera Felipe s/n, 35016 Las Palmas de Gran Canaria, Spain.
FAU - Almeida-Gonzalez, Maira
AU  - Almeida-Gonzalez M
AD  - Toxicology Unit, Research Institute of Biomedical and Health Sciences (IUIBS), 
      University of Las Palmas de Gran Canaria, Cabrera Felipe s/n, 35016 Las Palmas de 
      Gran Canaria, Spain; Spanish Biomedical Research Centre in Physiopathology of 
      Obesity and Nutrition (CIBERObn), Paseo Blas Cabrera Felipe s/n, 35016 Las Palmas 
      de Gran Canaria, Spain.
FAU - Zumbado, Manuel
AU  - Zumbado M
AD  - Toxicology Unit, Research Institute of Biomedical and Health Sciences (IUIBS), 
      University of Las Palmas de Gran Canaria, Cabrera Felipe s/n, 35016 Las Palmas de 
      Gran Canaria, Spain; Spanish Biomedical Research Centre in Physiopathology of 
      Obesity and Nutrition (CIBERObn), Paseo Blas Cabrera Felipe s/n, 35016 Las Palmas 
      de Gran Canaria, Spain.
FAU - Luzardo, Octavio P
AU  - Luzardo OP
AD  - Toxicology Unit, Research Institute of Biomedical and Health Sciences (IUIBS), 
      University of Las Palmas de Gran Canaria, Cabrera Felipe s/n, 35016 Las Palmas de 
      Gran Canaria, Spain; Spanish Biomedical Research Centre in Physiopathology of 
      Obesity and Nutrition (CIBERObn), Paseo Blas Cabrera Felipe s/n, 35016 Las Palmas 
      de Gran Canaria, Spain. Electronic address: octavio.perez@ulpgc.es.
LA  - eng
PT  - Journal Article
DEP - 20160417
PL  - Netherlands
TA  - Sci Total Environ
JT  - The Science of the total environment
JID - 0330500
RN  - 0 (Environmental Pollutants)
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Polycyclic Aromatic Hydrocarbons)
SB  - IM
MH  - Animals
MH  - Dog Diseases/blood/epidemiology/*parasitology
MH  - Dogs
MH  - Environmental Exposure/statistics & numerical data
MH  - Environmental Pollutants/*blood/toxicity
MH  - Hydrocarbons, Chlorinated/*blood/toxicity
MH  - Nematode Infections/blood/epidemiology/veterinary
MH  - Polycyclic Aromatic Hydrocarbons/*blood/toxicity
MH  - Spain
OTO - NOTNLM
OT  - Dirofilaria immitis
OT  - Dogs
OT  - Organochlorine pesticides
OT  - Parasites
OT  - Polychlorinated biphenyls
OT  - Polycyclic aromatic hydrocarbons
EDAT- 2016/04/21 06:00
MHDA- 2018/02/09 06:00
CRDT- 2016/04/21 06:00
PHST- 2016/02/15 00:00 [received]
PHST- 2016/03/26 00:00 [revised]
PHST- 2016/03/26 00:00 [accepted]
PHST- 2016/04/21 06:00 [entrez]
PHST- 2016/04/21 06:00 [pubmed]
PHST- 2018/02/09 06:00 [medline]
AID - S0048-9697(16)30627-1 [pii]
AID - 10.1016/j.scitotenv.2016.03.204 [doi]
PST - ppublish
SO  - Sci Total Environ. 2016 Aug 15;562:128-135. doi: 10.1016/j.scitotenv.2016.03.204. 
      Epub 2016 Apr 17.