PMID- 27097042
OWN - NLM
STAT- MEDLINE
DCOM- 20170602
LR  - 20170602
IS  - 1543-2742 (Electronic)
IS  - 1526-484X (Linking)
VI  - 26
IP  - 6
DP  - 2016 Dec
TI  - Influence of Post-Exercise Carbohydrate-Protein Ingestion on Muscle Glycogen 
      Metabolism in Recovery and Subsequent Running Exercise.
PG  - 572-580
LID - 10.1123/ijsnem.2016-0021 [doi]
AB  - We examined whether carbohydrate-protein ingestion influences muscle glycogen 
      metabolism during short-term recovery from exhaustive treadmill running and 
      subsequent exercise. Six endurance-trained individuals underwent two trials in a 
      randomized double-blind design, each involving an initial run-to-exhaustion at 
      70% VO(2max) (Run-1) followed by 4-h recovery (REC) and subsequent 
      run-to-exhaustion at 70% VO(2max) (Run-2). Carbohydrate-protein (CHO-P; 0.8 g 
      carbohydrate.kg body mass [BM(-1)].h(-1) plus 0.4 g protein.kg BM(-1).h(-1)) or 
      isocaloric carbohydrate (CHO; 1.2 g carbohydrate.kg BM(-1).h(-1)) beverages were 
      ingested at 30-min intervals during recovery. Muscle biopsies were taken upon 
      cessation of Run-1, postrecovery and fatigue in Run-2. Time-to-exhaustion in 
      Run-1 was similar with CHO and CHO-P (81 +/- 17 and 84 +/- 19 min, respectively). 
      Muscle glycogen concentrations were similar between treatments after Run-1 (99 +/- 
      3 mmol.kg dry mass [dm(-1)]). During REC, muscle glycogen concentrations 
      increased to 252 +/- 45 mmol.kg dm(-1) in CHO and 266 +/- 30 mmol.kg dm(-1) in CHO-P 
      (p = .44). Muscle glycogen degradation during Run-2 was similar between trials 
      (3.3 +/- 1.4 versus 3.5 +/- 1.9 mmol.kg dm(-1).min(-1) in CHO and CHO-P, 
      respectively) and no differences were observed at the respective points of 
      exhaustion (93 +/- 21 versus 100 +/- 11 mmol.kg dm(-1); CHO and CHO-P, respectively). 
      Similarly, time-to-exhaustion was not different between treatments in Run-2 (51 +/- 
      13 and 49 +/- 15 min in CHO and CHO-P, respectively). Carbohydrate-protein 
      ingestion equally accelerates muscle glycogen resynthesis during short-term 
      recovery from exhaustive running as when 1.2 g carbohydrate.kg BM(-1).h(-1) are 
      ingested. The addition of protein did not alter muscle glycogen utilization or 
      time to fatigue during repeated exhaustive running.
FAU - Alghannam, Abdullah F
AU  - Alghannam AF
FAU - Jedrzejewski, Dawid
AU  - Jedrzejewski D
FAU - Bilzon, James
AU  - Bilzon J
FAU - Thompson, Dylan
AU  - Thompson D
FAU - Tsintzas, Kostas
AU  - Tsintzas K
FAU - Betts, James A
AU  - Betts JA
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20160824
PL  - United States
TA  - Int J Sport Nutr Exerc Metab
JT  - International journal of sport nutrition and exercise metabolism
JID - 100939812
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Proteins)
RN  - 0 (Fatty Acids, Nonesterified)
RN  - 0 (Insulin)
RN  - 33X04XA5AT (Lactic Acid)
RN  - 8W8T17847W (Urea)
RN  - 9005-79-2 (Glycogen)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Blood Glucose/metabolism
MH  - Body Mass Index
MH  - Body Weight
MH  - Dietary Carbohydrates/*administration & dosage
MH  - Dietary Proteins/*administration & dosage
MH  - Double-Blind Method
MH  - Exercise Test
MH  - Fatigue/prevention & control
MH  - Fatty Acids, Nonesterified/blood
MH  - Female
MH  - Glycogen/metabolism
MH  - Glycogenolysis/drug effects
MH  - Humans
MH  - Insulin/blood
MH  - Lactic Acid/blood
MH  - Male
MH  - Muscle, Skeletal/*drug effects/metabolism
MH  - Oxygen Consumption
MH  - Physical Endurance
MH  - *Running
MH  - *Sports Nutritional Physiological Phenomena
MH  - Urea/blood
MH  - Urinalysis
MH  - Young Adult
OTO - NOTNLM
OT  - amino acids
OT  - metabolism
OT  - nutrition
OT  - performance
OT  - post-exercise
EDAT- 2016/04/21 06:00
MHDA- 2017/06/03 06:00
CRDT- 2016/04/21 06:00
PHST- 2016/04/21 06:00 [pubmed]
PHST- 2017/06/03 06:00 [medline]
PHST- 2016/04/21 06:00 [entrez]
AID - 2016-0021 [pii]
AID - 10.1123/ijsnem.2016-0021 [doi]
PST - ppublish
SO  - Int J Sport Nutr Exerc Metab. 2016 Dec;26(6):572-580. doi: 
      10.1123/ijsnem.2016-0021. Epub 2016 Aug 24.