PMID- 27097405
OWN - NLM
STAT- MEDLINE
DCOM- 20160516
LR  - 20160421
IS  - 1001-5302 (Print)
IS  - 1001-5302 (Linking)
VI  - 40
IP  - 22
DP  - 2015 Nov
TI  - [Relationship between autophagy and T2DM and intervention effect of traditional 
      Chinese medicine].
PG  - 4351-4
AB  - Insulin resistance and insulin secretion deficiency are main machanisms in 
      inducing type 2 diabetes mellitus (T2DM), and mitochondria damage plays an 
      important role in them. Research shows that autophagy is a self-protective 
      mechanism of cells, which plays an important role in maintaining the normal 
      structure and function of pancreatic beta cells and improving insulin resistance. 
      Previous studies show that traditional Chinese medicine can regulate cell 
      autophagy to influence beta cells and insulin resistance, type 2 diabetes mellitus 
      and its complications. Thus this review will talk about the process of the 
      relationship between autophagy and T2DM and the intervention effect of 
      traditional Chinese medicine.
FAU - Hong, Jin-ni
AU  - Hong JN
FAU - Li, Wei-wei
AU  - Li WW
FAU - Wang, Xue-mei
AU  - Wang XM
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - China
TA  - Zhongguo Zhong Yao Za Zhi
JT  - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese 
      materia medica
JID - 8913656
RN  - 0 (Drugs, Chinese Herbal)
RN  - 0 (Insulin)
SB  - IM
MH  - Animals
MH  - Autophagy/*drug effects
MH  - Diabetes Mellitus, Type 2/*drug therapy/metabolism/physiopathology
MH  - Drugs, Chinese Herbal/*therapeutic use
MH  - Humans
MH  - Insulin/metabolism
MH  - Insulin Resistance
MH  - Insulin-Secreting Cells/cytology/drug effects/metabolism
EDAT- 2016/04/22 06:00
MHDA- 2016/05/18 06:00
CRDT- 2016/04/22 06:00
PHST- 2016/04/22 06:00 [entrez]
PHST- 2016/04/22 06:00 [pubmed]
PHST- 2016/05/18 06:00 [medline]
PST - ppublish
SO  - Zhongguo Zhong Yao Za Zhi. 2015 Nov;40(22):4351-4.