PMID- 27106489
OWN - NLM
STAT- MEDLINE
DCOM- 20180102
LR  - 20181202
IS  - 1432-0932 (Electronic)
IS  - 0940-6719 (Linking)
VI  - 25
IP  - 8
DP  - 2016 Aug
TI  - Can facet joint fluid on MRI and dynamic instability be a predictor of 
      improvement in back pain following lumbar fusion for degenerative 
      spondylolisthesis?
PG  - 2408-15
LID - 10.1007/s00586-016-4525-1 [doi]
AB  - PURPOSE: To investigate the relationship between lumbar facet fluid and dynamic 
      instability in degenerative spondylolisthesis (DS), as well as the relationship 
      between facet fluid and patient-reported outcomes following a posterior lumbar 
      fusion. METHODS: We analyzed consecutive patients with degenerative 
      spondylolisthesis undergoing single level posterior lumbar fusion from December 
      2010 to January 2013 at a single academic institution. We investigated the 
      relationship between fluid in the facet joint as measured on axial MRI and the 
      presence of dynamic instability. We investigated the impact of facet fluid, Modic 
      changes, and dynamic instability on patient-reported outcomes. RESULTS: There was 
      a significant association between the amount of facet joint fluid and the 
      presence of dynamic instability (p = 0.03); as facet fluid increases, the 
      probability of dynamic instability also increases. For every 1 mm of facet fluid, 
      there was a 41.6 % increase (95 % CI 1.8-97) in the odds of dynamic instability. 
      A facet fluid amount less than 0.5 mm gave a 90 % probability that there was no 
      dynamic instability. The presence of facet fluid and dynamic instability were 
      associated with achieving minimal clinical important difference (MCID) in low 
      back pain following lumbar fusion (p = 0.04 and 0.05, respectively). CONCLUSION: 
      Facet joint fluid is associated with the presence of dynamic instability in DS. 
      The presence of facet fluid and dynamic instability may predict increased 
      likelihood of achieving MCID for improvement in back pain following posterior 
      lumbar fusion.
FAU - Snoddy, Mark C
AU  - Snoddy MC
AD  - Department of Orthopaedic Surgery, Vanderbilt University Medical Center, 
      Nashville, TN, USA.
FAU - Sielatycki, John A
AU  - Sielatycki JA
AD  - Department of Orthopaedic Surgery, Vanderbilt University Medical Center, 
      Nashville, TN, USA.
FAU - Sivaganesan, Ahilan
AU  - Sivaganesan A
AD  - Department of Neurosurgery, Vanderbilt University Medical Center, Nashville, TN, 
      USA.
FAU - Engstrom, Stephen M
AU  - Engstrom SM
AD  - Department of Orthopaedic Surgery, Vanderbilt University Medical Center, 
      Nashville, TN, USA.
FAU - McGirt, Matthew J
AU  - McGirt MJ
AD  - Carolina Neurosurgery and Spine Associates, Charlotte, NC, USA.
FAU - Devin, Clinton J
AU  - Devin CJ
AD  - Department of Orthopaedic Surgery, Vanderbilt University Medical Center, 
      Nashville, TN, USA. clinton.j.devin@vanderbilt.edu.
AD  - Vanderbilt Orthopaedic Institute, Medical Center East, South Tower, STE 4200, 
      1215 21st Avenue South, Nashville, TN, 37232, USA. 
      clinton.j.devin@vanderbilt.edu.
LA  - eng
PT  - Journal Article
DEP - 20160422
PL  - Germany
TA  - Eur Spine J
JT  - European spine journal : official publication of the European Spine Society, the 
      European Spinal Deformity Society, and the European Section of the Cervical Spine 
      Research Society
JID - 9301980
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Female
MH  - Humans
MH  - Low Back Pain/etiology
MH  - Lumbar Vertebrae/diagnostic imaging/*surgery
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - Minimal Clinically Important Difference
MH  - Prognosis
MH  - *Registries
MH  - Retrospective Studies
MH  - *Spinal Fusion
MH  - Spondylolisthesis/complications/diagnostic imaging/*surgery
MH  - Zygapophyseal Joint/*diagnostic imaging
OTO - NOTNLM
OT  - Back pain
OT  - Degenerative spondylolisthesis
OT  - Dynamic instability
OT  - Facet joint fluid
OT  - Magnetic resonance imaging
OT  - Patient-reported outcomes
EDAT- 2016/04/24 06:00
MHDA- 2018/01/03 06:00
CRDT- 2016/04/24 06:00
PHST- 2015/09/05 00:00 [received]
PHST- 2016/03/10 00:00 [accepted]
PHST- 2016/03/08 00:00 [revised]
PHST- 2016/04/24 06:00 [entrez]
PHST- 2016/04/24 06:00 [pubmed]
PHST- 2018/01/03 06:00 [medline]
AID - 10.1007/s00586-016-4525-1 [pii]
AID - 10.1007/s00586-016-4525-1 [doi]
PST - ppublish
SO  - Eur Spine J. 2016 Aug;25(8):2408-15. doi: 10.1007/s00586-016-4525-1. Epub 2016 
      Apr 22.