PMID- 27114420
OWN - NLM
STAT- MEDLINE
DCOM- 20170727
LR  - 20220409
IS  - 2005-1212 (Electronic)
IS  - 1976-2283 (Print)
IS  - 1976-2283 (Linking)
VI  - 10
IP  - 5
DP  - 2016 Sep 15
TI  - Antireflux Surgery in Korea: A Nationwide Study from 2011 to 2014.
PG  - 726-30
LID - 10.5009/gnl15406 [doi]
AB  - BACKGROUND/AIMS: Although laparoscopic fundoplication is a well-established 
      therapy for gastroesophageal reflux disease (GERD) in Western countries, the 
      mainstay of GERD treatment in Korea is long-term proton pump inhibitor (PPI) use. 
      The aim of the present study was to evaluate nationwide data regarding antireflux 
      surgery in Korea. METHODS: Data from 2011 to 2014 were collected from the Korean 
      Antireflux Surgery Study Group and then analyzed. RESULTS: A total of 87 patients 
      underwent laparoscopic fundoplication for the treatment of GERD. Preoperatively, 
      typical symptoms were present in 81 patients (93%) and atypical symptoms were 
      present in 51 patients (59%). Twenty-seven patients (31%) had poor PPI responses. 
      The average surgical time and postoperative hospital stay were 116.3+/-42.3 minutes 
      and 4.3+/-3.1 days, respectively. At 3 months after surgery, typical symptoms were 
      completely controlled in 86.3% of patients and partially controlled in 11.7%, 
      whereas atypical symptoms were completely controlled in 63.3% of patients and 
      partially controlled in 23.3%. CONCLUSIONS: This study showed that although 
      atypical symptoms and PPI nonresponders are common, the complete control rates of 
      typical and atypical symptoms were 86.3% and 63.3%, respectively. Laparoscopic 
      fundoplication is an efficacious method of controlling the symptoms of GERD and 
      has an acceptable rate of postoperative morbidity and adverse symptoms.
FAU - Lee, Jun-Hyun
AU  - Lee JH
AD  - Department of Surgery, The Catholic University of Korea College of Medicine, 
      Korea.
FAU - Park, Joong-Min
AU  - Park JM
AD  - Department of Surgery, Chung-Ang University College of Medicine, Seoul, Korea.
FAU - Han, Sang-Uk
AU  - Han SU
AD  - Department of Surgery, Ajou University School of Medicine, Suwon, Korea.
FAU - Kim, Jin-Jo
AU  - Kim JJ
AD  - Department of Surgery, The Catholic University of Korea College of Medicine, 
      Korea.
FAU - Song, Kyo Young
AU  - Song KY
AD  - Department of Surgery, The Catholic University of Korea College of Medicine, 
      Korea.
FAU - Ryu, Seung Wan
AU  - Ryu SW
AD  - Department of Surgery, Keimyung University School of Medicine, Daegu, Korea.
FAU - Seo, Kyung Won
AU  - Seo KW
AD  - Department of Surgery, Kosin University College of Medicine, Busan, Korea.
FAU - Kim, Hyoung-Il
AU  - Kim HI
AD  - Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.
FAU - Kim, Wook
AU  - Kim W
AD  - Department of Surgery, The Catholic University of Korea College of Medicine, 
      Korea.
CN  - Korean Antireflux Surgery Study (KARS) Group
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PL  - Korea (South)
TA  - Gut Liver
JT  - Gut and liver
JID - 101316452
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Female
MH  - Fundoplication/methods/*statistics & numerical data
MH  - Gastroesophageal Reflux/drug therapy/*surgery
MH  - Humans
MH  - Laparoscopy/methods/*statistics & numerical data
MH  - Male
MH  - Middle Aged
MH  - Proton Pump Inhibitors/therapeutic use
MH  - Republic of Korea
MH  - Treatment Outcome
PMC - PMC5003195
OTO - NOTNLM
OT  - Gastroesophageal reflux disease
OT  - Laparoscopic fundoplication
OT  - Nationwide Korean data
OT  - Proton pump inhibitors
EDAT- 2016/04/27 06:00
MHDA- 2017/07/28 06:00
PMCR- 2016/09/01
CRDT- 2016/04/27 06:00
PHST- 2015/08/20 00:00 [received]
PHST- 2015/11/16 00:00 [revised]
PHST- 2015/11/16 00:00 [accepted]
PHST- 2016/04/27 06:00 [entrez]
PHST- 2016/04/27 06:00 [pubmed]
PHST- 2017/07/28 06:00 [medline]
PHST- 2016/09/01 00:00 [pmc-release]
AID - gnl15406 [pii]
AID - gnl-10-726 [pii]
AID - 10.5009/gnl15406 [doi]
PST - ppublish
SO  - Gut Liver. 2016 Sep 15;10(5):726-30. doi: 10.5009/gnl15406.