PMID- 27114982
OWN - PIP
STAT- PubMed-not-MEDLINE
DCOM- 20160426
LR  - 20181113
IS  - 2251-6085 (Print)
IS  - 2251-6093 (Electronic)
IS  - 2251-6085 (Linking)
VI  - 45
IP  - 2
DP  - 2016 Feb
TI  - Effect of Omega-3 Supplementation on Lipocalin 2 and Retinol-Binding Protein 4 in 
      Type 2 Diabetic Patients.
PG  - 179-85
AB  - BACKGROUND: Serum levels of lipocalin 2 (LCN 2) and retinol-binding protein-4 
      (RBP 4), increase in type 2 diabetes mellitus (T2DM). We sought to determine 
      whether serum LCN 2 and RBP 4 change after an intervention with omega-3 fatty 
      acids supplementation in diabetic patients. METHODS: Forty-five type 2 diabetic 
      patients from Iranian Diabetic Association in Tehran, Iran in 2013 were randomly 
      recruited into two groups: one group received 4 g/d omega-3 for 10 wk; and the 
      control group received placebo. Blood samples, food intake records, 
      anthropometric measurements were obtained from all participants at the beginning 
      and end of the study. RESULTS: Fasting RBP 4 plasma levels significantly changed 
      after 10 wk supplementation (P = 0.01). The LCN 2 concentrations decreased in 
      omega-3 group, but the changes were not statistically significant. Omega-3 
      supplementation had no noticeable effect on anthropometric factors. CONCLUSION: 
      These findings provide a rationale for omega-3 supplements aimed at lowering 
      serum RBP 4 levels in T2DM.
FAU - Farahbakhsh-Farsi, Payam
AU  - Farahbakhsh-Farsi P
AD  - Dept. of Cellular and Molecular Nutrition, School of Nutritional Sciences and 
      Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
FAU - Djazayery, Abolghassem
AU  - Djazayery A
AD  - Dept. of Community Nutrition, School of Nutritional Sciences and Dietetics, 
      Tehran University of Medical Sciences, Tehran, Iran.
FAU - Eshraghian, Mohammad Reza
AU  - Eshraghian MR
AD  - Dept. of Biostatistics, School of Public Health, Tehran University of Medical 
      Sciences, Tehran, Iran.
FAU - Koohdani, Fariba
AU  - Koohdani F
AD  - Dept. of Cellular and Molecular Nutrition, School of Nutritional Sciences and 
      Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
FAU - Zarei, Mahnaz
AU  - Zarei M
AD  - Dept. of Cellular and Molecular Nutrition, School of Nutritional Sciences and 
      Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
FAU - Javanbakht, Mohammad Hassan
AU  - Javanbakht MH
AD  - Dept. of Cellular and Molecular Nutrition, School of Nutritional Sciences and 
      Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
FAU - Derakhshanian, Hoda
AU  - Derakhshanian H
AD  - Dept. of Cellular and Molecular Nutrition, School of Nutritional Sciences and 
      Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
FAU - Djalali, Mahmoud
AU  - Djalali M
AD  - Dept. of Cellular and Molecular Nutrition, School of Nutritional Sciences and 
      Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
LA  - eng
PT  - Journal Article
PL  - Iran
TA  - Iran J Public Health
JT  - Iranian journal of public health
JID - 7505531
PMC - PMC4841872
OTO - NOTNLM
OT  - Diabetes mellitus
OT  - Lipocalin
OT  - Omega-3 fatty acid
OT  - Retinol-binding protein
EDAT- 2016/04/27 06:00
MHDA- 2016/04/27 06:01
PMCR- 2016/02/01
CRDT- 2016/04/27 06:00
PHST- 2016/04/27 06:00 [entrez]
PHST- 2016/04/27 06:00 [pubmed]
PHST- 2016/04/27 06:01 [medline]
PHST- 2016/02/01 00:00 [pmc-release]
AID - ijph-45-179 [pii]
PST - ppublish
SO  - Iran J Public Health. 2016 Feb;45(2):179-85.