PMID- 27118163 OWN - NLM STAT- MEDLINE DCOM- 20180321 LR - 20220408 IS - 1873-460X (Electronic) IS - 1056-8727 (Print) IS - 1056-8727 (Linking) VI - 30 IP - 6 DP - 2016 Aug TI - Diabetes distress in adults with type 1 diabetes: Prevalence, incidence and change over time. PG - 1123-8 LID - S1056-8727(16)30088-5 [pii] LID - 10.1016/j.jdiacomp.2016.03.032 [doi] AB - AIMS: To document the prevalence and 9-month incidence of elevated diabetes distress (DD) and the stability of DD over time using both single threshold and minimal clinically important differences (MCID) approaches. METHODS: Adults with type 1 diabetes (T1D) (N=224) completed the 28-item T1-Diabetes Distress Scale (T1-DDS) at baseline and 9months. A T1-DDS threshold was identified with spline analysis and MCID was calculated from the standard error of measurement. RESULTS: Analyses supported a cut-point of >/=2.0 for elevated DD. The prevalence and 9-month incidence of elevated DD was 42.1% and 54.4%, respectively. MCID was +/-0.19 but varied by subscale (.26 to .50). Elevated DD was stable: only 20% crossed 2.0 over 9months. MCID analyses showed that change also occurred among those who remained either below or above 2.0 over time. Change varied by source of distress, with Powerlessness the most prevalent and stable. Using MCID, only participant age, gender and number of complications predicted change. CONCLUSIONS: The prevalence, 9-month incidence and stability of elevated DD are high among adults with T1D, with change based on source of DD. We propose a combined cut-point/MCID framework for measuring change in DD, since each approach reflects unique characteristics of change over time. CI - Copyright (c) 2016 Elsevier Inc. All rights reserved. FAU - Fisher, Lawrence AU - Fisher L AD - Department of Family & Community Medicine, University of California,s San Francisco, San Francisco, CA, USA. Electronic address: larry.fisher@ucsf.edu. FAU - Hessler, Danielle AU - Hessler D AD - Department of Family & Community Medicine, University of California,s San Francisco, San Francisco, CA, USA. FAU - Polonsky, William AU - Polonsky W AD - Department of Psychiatry, University of California, San Diego, San Diego, CA, USA; Behavioral Diabetes Institute, San Diego, CA, USA. FAU - Strycker, Lisa AU - Strycker L AD - Oregon Research Institute, Eugene, OR, USA. FAU - Masharani, Umesh AU - Masharani U AD - Department of Medicine, University of California, San Francisco, San Francisco, CA, USA. FAU - Peters, Anne AU - Peters A AD - University of Southern California, Los Angeles, CA, USA. LA - eng GR - R01 DK094863/DK/NIDDK NIH HHS/United States PT - Journal Article DEP - 20160404 PL - United States TA - J Diabetes Complications JT - Journal of diabetes and its complications JID - 9204583 SB - IM MH - Adult MH - Diabetes Mellitus, Type 1/*psychology MH - Emotions MH - Female MH - Humans MH - Incidence MH - Male MH - Middle Aged MH - Prevalence MH - Stress, Psychological/*epidemiology PMC - PMC4949147 MID - NIHMS776211 OTO - NOTNLM OT - Change over time OT - Diabetes distress OT - Incidence OT - Predictors of change OT - Prevalence COIS- Competing Interests No author reported a conflict of interest. Lawrence Fisher: consultant to or advisory board member for Roche Diagnostics, Elli Lilly, Novo Nordisk, Sanofi, Abbott Diabetes Care; William Polonsky: consultant or advisory board with Sanofi, Novo Nordisk, Elli Lilly, Dexcom, Abbott, J&J, Boehringer Ingelheim, Takeda, Roche; Anne Peters: consultant or advisory board with Amgen, Abbott Diabetes Care, Becton Dickinson, Biodel, Bristol Myers Squibb/Astra-Zeneca, Janssen, Lexicon, Lilly, Medtronic Minimed, Novo Nordisk, OptumRx, sanofi, Takeda, Thermalin. Speakers bureau - Bristol Myers Squibb/Astra-Zeneca, Novo Nordisk, Janssen. EDAT- 2016/04/28 06:00 MHDA- 2018/03/22 06:00 PMCR- 2017/08/01 CRDT- 2016/04/28 06:00 PHST- 2016/02/23 00:00 [received] PHST- 2016/03/23 00:00 [revised] PHST- 2016/03/24 00:00 [accepted] PHST- 2016/04/28 06:00 [entrez] PHST- 2016/04/28 06:00 [pubmed] PHST- 2018/03/22 06:00 [medline] PHST- 2017/08/01 00:00 [pmc-release] AID - S1056-8727(16)30088-5 [pii] AID - 10.1016/j.jdiacomp.2016.03.032 [doi] PST - ppublish SO - J Diabetes Complications. 2016 Aug;30(6):1123-8. doi: 10.1016/j.jdiacomp.2016.03.032. Epub 2016 Apr 4.