PMID- 27122736 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20160428 LR - 20201001 IS - 1011-6842 (Print) IS - 1011-6842 (Linking) VI - 29 IP - 5 DP - 2013 Sep TI - Chronic Kidney Disease, But Not Diabetes, Can Predict 30-Day Outcomes in Patients with ST-Elevation Myocardial Infarction after Primary Percutaneous Coronary Intervention: A Single-Center Experience. PG - 395-403 AB - BACKGROUND: Patients with acute coronary syndrome and impaired renal function have been shown to have high mortality. However, there is scarce literature to date addressing the impact of diabetes mellitus (DM) and renal function on clinical outcomes of ST elevation myocardial infarction (STEMI) in Taiwan. METHOD: This study enrolled 512 STEMI patients who received primary percutaneous coronary intervention. Patients were divided into 4 groups including group 1: patients without DM or CKD (nDM-nCKD); group 2: patients with DM but without CKD (DM-nCKD); group 3: patients with CKD but without DM (nDM-CKD); group 4: patients with DM and CKD (DM-CKD). Patients were also classified into four groups based on their estimated glomerular filtration rates (eGFR): stage 1 (eGFR >/= 90 ml/min/1.73 m(2), n = 163), stage 2 (eGFR = 89-60 ml/min/1.73 m(2), n = 171), stage 3 (eGFR = 59-30 ml/min/1.73 m(2), n = 136), and stage 4 (eGFR < 30 ml/min/1.73 m(2), n = 42). The complication rates, length of hospital stay, and 30-day outcomes were analyzed. RESULTS: The patients in both the nDM-CKD group and DM-CKD group had higher incidences of hypotension, intra-aortic balloon counterpulsation use, and respiratory failure (p < 0.005). They had significantly longer hospital stay and 30-day mortality rates (p < 0.001). The patients with CKD stage 3 and 4 had longer hospital stay and higher 30-day mortality rates (p < 0.001). However, DM was not an independent factor on the length of hospital stay and 30-day mortality rates. CONCLUSIONS: STEMI patients with impaired renal function, but not DM, had significantly longer hospital stay and higher 30-day mortality rates. KEY WORDS: Chronic kidney disease; Diabetes mellitus; Mortality; Primary percutaneous coronary intervention; ST-segment elevation myocardial infarction. FAU - Hung, Cheng-Chung AU - Hung CC AD - Cardiovascular Medical Center, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; FAU - Huang, Wei-Chun AU - Huang WC AD - Cardiovascular Medical Center, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; ; School of Medicine, National Yang-Ming University, Taipei, Taiwan; ; Department of Physical Therapy, Fooyin University; FAU - Chiou, Kuan-Rau AU - Chiou KR AD - Cardiovascular Medical Center, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; ; School of Medicine, National Yang-Ming University, Taipei, Taiwan; FAU - Cheng, Chin-Chang AU - Cheng CC AD - Cardiovascular Medical Center, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; ; School of Medicine, National Yang-Ming University, Taipei, Taiwan; FAU - Kuo, Feng-Yu AU - Kuo FY AD - Cardiovascular Medical Center, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; FAU - Yang, Jin-Shiou AU - Yang JS AD - Department of Physical Therapy, Fooyin University; FAU - Lin, Ko-Long AU - Lin KL AD - Department of Physical Medicine and Rehabilitation, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; FAU - Chiang, Cheng-Hung AU - Chiang CH AD - Cardiovascular Medical Center, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; FAU - Hsiao, Shin-Hung AU - Hsiao SH AD - Cardiovascular Medical Center, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; ; School of Medicine, National Yang-Ming University, Taipei, Taiwan; FAU - Lai, Chi-Cheng AU - Lai CC AD - Cardiovascular Medical Center, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; ; School of Medicine, National Yang-Ming University, Taipei, Taiwan; FAU - Lin, Tzu-Wen AU - Lin TW AD - Cheng Shiu University, Kaohsiung, Taiwan. FAU - Mar, Guang-Yuan AU - Mar GY AD - Cardiovascular Medical Center, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; FAU - Chiou, Chuen-Wang AU - Chiou CW AD - Cardiovascular Medical Center, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; ; School of Medicine, National Yang-Ming University, Taipei, Taiwan; FAU - Liu, Chun-Peng AU - Liu CP AD - Cardiovascular Medical Center, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; ; School of Medicine, National Yang-Ming University, Taipei, Taiwan; LA - eng PT - Journal Article PL - China (Republic : 1949- ) TA - Acta Cardiol Sin JT - Acta Cardiologica Sinica JID - 101687085 PMC - PMC4804788 EDAT- 2013/09/01 00:00 MHDA- 2013/09/01 00:01 PMCR- 2013/09/01 CRDT- 2016/04/29 06:00 PHST- 2016/04/29 06:00 [entrez] PHST- 2013/09/01 00:00 [pubmed] PHST- 2013/09/01 00:01 [medline] PHST- 2013/09/01 00:00 [pmc-release] PST - ppublish SO - Acta Cardiol Sin. 2013 Sep;29(5):395-403.