PMID- 27122800
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160428
LR  - 20201001
IS  - 1011-6842 (Print)
IS  - 1011-6842 (Linking)
VI  - 30
IP  - 4
DP  - 2014 Jul
TI  - Gender and Age Differences in Short- and Long-Term Outcomes Following Primary 
      Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction.
PG  - 274-83
AB  - BACKGROUND: Studies have reported that women with ST elevation myocardial 
      infarction (STEMI) have worse short- and long-term outcomes than men. It has not 
      yet been confirmed whether these differences reflect differences in age between 
      men and women. METHODS: We retrospectively enrolled 1035 consecutive STEMI 
      patients treated with primary percutaneous coronary intervention (PCI). Baseline 
      clinical characteristics, coronary anatomy, and outcome were compared between 
      young (< 65 years old) and older patients (>/= 65 years old) of both sexes. 
      RESULTS: Younger women presented with a lower incidence of typical angina (83% 
      vs. 93%, p = 0.03), single-vessel disease (21% vs. 35%, p = 0.03), and total 
      occlusion of infarct-related artery (65% vs. 83%, p = 0.001) than younger men, 
      with no gender difference noted in the older group. Younger women in the study 
      had a higher incidence of reinfarction, heart failure requiring admission, or 
      mortality (23% vs. 6%, p < 0.001) during follow-up, compared with younger men, 
      with no gender difference in the older group. Using the Kaplan-Meier analysis, 
      younger women had lower rates of event-free survival (p < 0.001 by log-rank test) 
      than younger men, with no gender difference in the older group. In multivariate 
      analysis, age could predict long-term outcome in men (Hazard ratio 4.43, 95% 
      confidence interval: 2.89-6.78, p < 0.001) but not in women. CONCLUSIONS: In 
      STEMI patients receiving primary PCI, sex-related long-term outcome differences 
      were age-dependent, with younger women likely to have a worse long-term outcome 
      when compared with younger men. KEY WORDS: Coronary heart disease; Gender; 
      Myocardial infarction.
FAU - Chua, Su-Kiat
AU  - Chua SK
AD  - Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical 
      University; ; Department of General Medicine; ; Division of Cardiology, 
      Department of Internal Medicine, Shin Kong Wu Ho-Su Memorial Hospital, Taipei;
FAU - Shyu, Kou-Gi
AU  - Shyu KG
AD  - Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical 
      University; ; Division of Cardiology, Department of Internal Medicine, Shin Kong 
      Wu Ho-Su Memorial Hospital, Taipei;
FAU - Hung, Huei-Fong
AU  - Hung HF
AD  - Division of Cardiology, Department of Internal Medicine, Shin Kong Wu Ho-Su 
      Memorial Hospital, Taipei;
FAU - Cheng, Jun-Jack
AU  - Cheng JJ
AD  - Division of Cardiology, Department of Internal Medicine, Shin Kong Wu Ho-Su 
      Memorial Hospital, Taipei; ; School of Medicine, Fu Jen Catholic University, New 
      Taipei City, Taiwan.
FAU - Lo, Huey-Ming
AU  - Lo HM
AD  - Division of Cardiology, Department of Internal Medicine, Shin Kong Wu Ho-Su 
      Memorial Hospital, Taipei; ; School of Medicine, Fu Jen Catholic University, New 
      Taipei City, Taiwan.
FAU - Liu, Shih-Chi
AU  - Liu SC
AD  - Division of Cardiology, Department of Internal Medicine, Shin Kong Wu Ho-Su 
      Memorial Hospital, Taipei;
FAU - Chen, Lung-Ching
AU  - Chen LC
AD  - Division of Cardiology, Department of Internal Medicine, Shin Kong Wu Ho-Su 
      Memorial Hospital, Taipei;
FAU - Chiu, Chiung-Zuan
AU  - Chiu CZ
AD  - Division of Cardiology, Department of Internal Medicine, Shin Kong Wu Ho-Su 
      Memorial Hospital, Taipei; ; School of Medicine, Fu Jen Catholic University, New 
      Taipei City, Taiwan.
FAU - Chang, Che-Ming
AU  - Chang CM
AD  - Division of Cardiology, Department of Internal Medicine, Shin Kong Wu Ho-Su 
      Memorial Hospital, Taipei;
FAU - Lin, Shen-Chang
AU  - Lin SC
AD  - Division of Cardiology, Department of Internal Medicine, Shin Kong Wu Ho-Su 
      Memorial Hospital, Taipei;
FAU - Liou, Jer-Young
AU  - Liou JY
AD  - Division of Cardiology, Department of Internal Medicine, Shin Kong Wu Ho-Su 
      Memorial Hospital, Taipei;
FAU - Lee, Shih-Huang
AU  - Lee SH
AD  - Division of Cardiology, Department of Internal Medicine, Shin Kong Wu Ho-Su 
      Memorial Hospital, Taipei; ; School of Medicine, Fu Jen Catholic University, New 
      Taipei City, Taiwan.
LA  - eng
PT  - Journal Article
PL  - China (Republic : 1949- )
TA  - Acta Cardiol Sin
JT  - Acta Cardiologica Sinica
JID - 101687085
PMC - PMC4804989
EDAT- 2014/07/01 00:00
MHDA- 2014/07/01 00:01
PMCR- 2014/07/01
CRDT- 2016/04/29 06:00
PHST- 2016/04/29 06:00 [entrez]
PHST- 2014/07/01 00:00 [pubmed]
PHST- 2014/07/01 00:01 [medline]
PHST- 2014/07/01 00:00 [pmc-release]
PST - ppublish
SO  - Acta Cardiol Sin. 2014 Jul;30(4):274-83.