PMID- 27123771 OWN - NLM STAT- MEDLINE DCOM- 20180129 LR - 20190318 IS - 1873-6750 (Electronic) IS - 0160-4120 (Linking) VI - 92-93 DP - 2016 Jul-Aug TI - Concentrations of organochlorine pesticides in umbilical cord blood and related lifestyle and dietary intake factors among pregnant women of the Huaihe River Basin in China. PG - 276-83 LID - S0160-4120(16)30147-7 [pii] LID - 10.1016/j.envint.2016.04.017 [doi] AB - Organochlorine pesticides (OCPs), one of the persistent organic pollutants (POPs) with highly lipophilic properties, long half-lives, and persistence in the environment, are prevalent in the environment even though they have been banned for >30years. We aimed to investigate the current OCP exposure levels in cord blood from healthy pregnant women residing in the Huaihe River Basin, China, and examined the association between OCP levels and dietary habits and lifestyle factors. In this study, we measured the exposure levels of 17 OCPs in the umbilical cord blood from 999 healthy pregnant women; we also administered 1000 self-reported questionnaires regarding the general characteristics and dietary habits of those women. Our results showed that rho,rho'-DDE, rho,rho'-DDT, aldrin, dieldrin, and methoxychlor, which had higher measured concentrations (2.01+/-1.89, 4.31+/-5.68, 7.29+/-8.74, 5.27+/-7.65, and 0.98+/-1.42ng/mL, respectively) and detection frequencies (99.69%, 100.00%, 81.79%, 75.00%, and 74.49%, respectively), were the predominant OCPs in cord blood, and the higher levels of DDTs, aldrin, dieldrin, and methoxychlor were mainly due to recent use. In addition, most of the HCHs in cord blood were derived not only from historical use of technical HCH, but also from the additional use of lindane. In addition, we found that the education level of the pregnant women and monthly household income were positively correlated with OCP levels, particularly rho,rho'-DDE, aldrin, and dieldrin. Furthermore, the consumption of red meat (pork, beef, and lamb), fish, and bean products may be an important contributing factor to the increased concentrations of OCPs in cord blood, while the intake of poultry and pickles was negatively correlated with aldrin level. This study is the first to provide adequate data on current OCP exposure levels in cord blood from pregnant women in the Huaihe River Basin. CI - Copyright (c) 2016 Elsevier Ltd. All rights reserved. FAU - Luo, Dan AU - Luo D AD - Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environment Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, #13 Hangkong Road, Wuhan, Hubei, 430030, China. FAU - Pu, Yabing AU - Pu Y AD - Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environment Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, #13 Hangkong Road, Wuhan, Hubei, 430030, China. FAU - Tian, Haoyuan AU - Tian H AD - Key Laboratory of Chemical Safety and Health, National Institute of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, #27 Nan Wei Road, West City District, Beijing 100050, China. FAU - Cheng, Juan AU - Cheng J AD - Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environment Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, #13 Hangkong Road, Wuhan, Hubei, 430030, China. FAU - Zhou, Tingting AU - Zhou T AD - Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environment Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, #13 Hangkong Road, Wuhan, Hubei, 430030, China. FAU - Tao, Yun AU - Tao Y AD - Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environment Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, #13 Hangkong Road, Wuhan, Hubei, 430030, China. FAU - Yuan, Jing AU - Yuan J AD - Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environment Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, #13 Hangkong Road, Wuhan, Hubei, 430030, China. FAU - Sun, Xin AU - Sun X AD - Key Laboratory of Chemical Safety and Health, National Institute of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, #27 Nan Wei Road, West City District, Beijing 100050, China. Electronic address: sunxin@chinacdc.cn. FAU - Mei, Surong AU - Mei S AD - Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environment Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, #13 Hangkong Road, Wuhan, Hubei, 430030, China. Electronic address: surongmei@hust.edu.cn. LA - eng PT - Journal Article DEP - 20160426 PL - Netherlands TA - Environ Int JT - Environment international JID - 7807270 RN - 0 (Environmental Pollutants) RN - 0 (Hydrocarbons, Chlorinated) RN - 0 (Pesticides) SB - IM MH - Animals MH - China MH - *Diet MH - Environmental Pollutants/*blood/chemistry MH - Female MH - Fetal Blood/*chemistry MH - Humans MH - Hydrocarbons, Chlorinated/analysis MH - Life Style MH - Pesticides/*blood MH - Pregnancy MH - Residence Characteristics MH - Rivers MH - Young Adult OTO - NOTNLM OT - *Dietary intake OT - *Huaihe River Basin OT - *Lifestyle factors OT - *Organochlorine pesticides OT - *Pregnant women OT - *Umbilical cord blood EDAT- 2016/04/29 06:00 MHDA- 2018/01/30 06:00 CRDT- 2016/04/29 06:00 PHST- 2015/11/20 00:00 [received] PHST- 2016/04/06 00:00 [revised] PHST- 2016/04/13 00:00 [accepted] PHST- 2016/04/29 06:00 [entrez] PHST- 2016/04/29 06:00 [pubmed] PHST- 2018/01/30 06:00 [medline] AID - S0160-4120(16)30147-7 [pii] AID - 10.1016/j.envint.2016.04.017 [doi] PST - ppublish SO - Environ Int. 2016 Jul-Aug;92-93:276-83. doi: 10.1016/j.envint.2016.04.017. Epub 2016 Apr 26.