PMID- 27127810
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20180718
LR  - 20180718
IS  - 1364-5528 (Electronic)
IS  - 0003-2654 (Linking)
VI  - 141
IP  - 11
DP  - 2016 May 23
TI  - Strong electrochemiluminescent interactions between carbon nitride 
      nanosheet-reduced graphene oxide nanohybrids and folic acid, and ultrasensitive 
      sensing for folic acid.
PG  - 3379-88
LID - 10.1039/c6an00664g [doi]
AB  - Graphite-like carbon nitride nanosheets (g-C3N4 NSs) have recently emerged as 
      electrochemiluminescent (ECL) nanomaterials and have attracted more and more 
      attention due to their excellent ECL properties and promising applications in ECL 
      sensing. However, the ECL study of g-C3N4 NSs is still in the early stages. Many 
      studies are required to reveal the exact ECL mechanisms of g-C3N4 NSs and thus 
      boost their sensing applications. In this paper, we have investigated ECL 
      interactions between folic acid (FA) and a g-C3N4 NS/S2O8(2-) ECL system at a 
      g-C3N4 NS-reduced graphene oxide (rGO) nanohybrid/glassy carbon electrode in 
      aqueous solutions. Compared with bare g-C3N4 NSs, the nanohybrids of g-C3N4 
      NS-rGO give a much stable ECL emission due to the prevention of over 
      electrochemical reduction of g-C3N4 by rGO. The stable ECL emission from the 
      g-C3N4 NS-rGO/S2O8(2-) ECL system can be strongly quenched by FA, even in a very 
      low concentration (pM levels). The ECL quenching mechanisms are investigated and 
      discussed in detail. Based on the strong interactions between FA and g-C3N4 NSs, 
      a novel, sensitive, stable and selective ECL sensor has been constructed for the 
      detection of FA, with a wide linear response range from 0.1 to 90 nM, and an 
      excellent detection limit (62 pM). This work not only further clarifies ECL 
      mechanisms of g-C3N4 NSs, but also suggests a promising application of the newly 
      emerging ECL nanomaterial.
FAU - Zhou, Chen
AU  - Zhou C
AD  - MOE Key Laboratory of Analysis and Detection Technology for Food Safety, Fujian 
      Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, 
      and College of Chemistry, Fuzhou University, Fujian 350108, China. 
      y.w.chi@fzu.edu.cn.
FAU - Chen, Yingmei
AU  - Chen Y
AD  - MOE Key Laboratory of Analysis and Detection Technology for Food Safety, Fujian 
      Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, 
      and College of Chemistry, Fuzhou University, Fujian 350108, China. 
      y.w.chi@fzu.edu.cn.
FAU - Shang, Pengxiang
AU  - Shang P
AD  - MOE Key Laboratory of Analysis and Detection Technology for Food Safety, Fujian 
      Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, 
      and College of Chemistry, Fuzhou University, Fujian 350108, China. 
      y.w.chi@fzu.edu.cn.
FAU - Chi, Yuwu
AU  - Chi Y
AD  - MOE Key Laboratory of Analysis and Detection Technology for Food Safety, Fujian 
      Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, 
      and College of Chemistry, Fuzhou University, Fujian 350108, China. 
      y.w.chi@fzu.edu.cn.
LA  - eng
PT  - Journal Article
PL  - England
TA  - Analyst
JT  - The Analyst
JID - 0372652
EDAT- 2016/04/30 06:00
MHDA- 2016/04/30 06:01
CRDT- 2016/04/30 06:00
PHST- 2016/04/30 06:00 [entrez]
PHST- 2016/04/30 06:00 [pubmed]
PHST- 2016/04/30 06:01 [medline]
AID - 10.1039/c6an00664g [doi]
PST - ppublish
SO  - Analyst. 2016 May 23;141(11):3379-88. doi: 10.1039/c6an00664g.