PMID- 27128664
OWN - NLM
STAT- MEDLINE
DCOM- 20170927
LR  - 20180109
IS  - 1530-0315 (Electronic)
IS  - 0195-9131 (Linking)
VI  - 48
IP  - 9
DP  - 2016 Sep
TI  - CHO Mouth Rinse Ameliorates Neuromuscular Response with Lower Endogenous CHO 
      Stores.
PG  - 1810-20
LID - 10.1249/MSS.0000000000000973 [doi]
AB  - PURPOSE: This study aimed to investigate carbohydrate (CHO) mouth rinse response 
      on neuromuscular activity, fuel oxidation rates, and cycling performance with 
      different initial levels of endogenous CHO availability. METHODS: In a 
      double-blind, randomized placebo-controlled design, eight males completed six 
      experimental mouth rinse trials: CHO (6.4% maltodextrin) or placebo solution in a 
      fed state (FED), 12-h fasted state (FAST), or a combined exercise-depleted muscle 
      glycogen and 12-h fasted state (DEP). Trials consisted of 30-min cycling at 90% 
      of gas exchange threshold, followed by a 20-km cycling time trial. Plasma 
      lactate, plasma glucose, oxygen uptake, and EMG activity were measured, and CHO 
      and fat oxidation rates were calculated. RESULTS: CHO mouth rinse maintained 
      higher plasma glucose levels as the constant load exercise progressed (P = 
      0.023). The reduced EMG activity in the DEP condition with the placebo during 
      constant load exercise was ameliorated with CHO mouth rinse (P < 0.01). 
      Furthermore, the power output and the EMG activity throughout the 20-km time 
      trial were reduced in the DEP condition with placebo but were both restored with 
      CHO mouth rinse (P < 0.05). Time trial performance was only improved with CHO in 
      the DEP compared with the corresponding placebo (P < 0.05), and no differences 
      between supplements were observed in the FED or FAST states. Analyses of the 
      qualitative inference showed "benefit very likely" of CHO mouth rinse on exercise 
      performance in DEP, "possibly benefit" in FAST, and "negligible or trivial" in 
      FED. CHO mouth rinse had no effect on CHO and fat oxidation rates in either 
      exercise mode. CONCLUSION: The CHO mouth rinse influences exercise performance 
      when endogenous CHO availability is low, and an enhanced central motor drive is 
      potentially the main influencing mechanism.
FAU - Ataide-Silva, Thays
AU  - Ataide-Silva T
AD  - 1Sports Science Research Group, Department of Physical Education and Sports 
      Science CAV, Federal University of Pernambuco, Pernambuco, BRAZIL; 2Endurance 
      Performance Research Group, School of Physical Education and Sport, University of 
      Sao Paulo, Sao Paulo, BRAZIL; and 3College of Health and Biomedicine and 
      Institute of Sport, Exercise and Active Living (ISEAL), Victoria University, 
      Melbourne, AUSTRALIA.
FAU - Ghiarone, Thaysa
AU  - Ghiarone T
FAU - Bertuzzi, Romulo
AU  - Bertuzzi R
FAU - Stathis, Christos George
AU  - Stathis CG
FAU - Leandro, Carol Gois
AU  - Leandro CG
FAU - Lima-Silva, Adriano Eduardo
AU  - Lima-Silva AE
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Med Sci Sports Exerc
JT  - Medicine and science in sports and exercise
JID - 8005433
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Mouthwashes)
RN  - 0 (Polysaccharides)
RN  - 33X04XA5AT (Lactic Acid)
RN  - 7CVR7L4A2D (maltodextrin)
SB  - IM
MH  - Adult
MH  - Blood Glucose/analysis
MH  - Dietary Carbohydrates/*administration & dosage
MH  - Double-Blind Method
MH  - Electromyography
MH  - Exercise/*physiology
MH  - Exercise Test
MH  - Humans
MH  - Lactic Acid/blood
MH  - Male
MH  - *Mouthwashes
MH  - Oxygen Consumption
MH  - Physical Endurance/*physiology
MH  - Polysaccharides
EDAT- 2016/04/30 06:00
MHDA- 2017/09/28 06:00
CRDT- 2016/04/30 06:00
PHST- 2016/04/30 06:00 [entrez]
PHST- 2016/04/30 06:00 [pubmed]
PHST- 2017/09/28 06:00 [medline]
AID - 10.1249/MSS.0000000000000973 [doi]
PST - ppublish
SO  - Med Sci Sports Exerc. 2016 Sep;48(9):1810-20. doi: 10.1249/MSS.0000000000000973.