PMID- 27129440
OWN - NLM
STAT- MEDLINE
DCOM- 20170718
LR  - 20180108
IS  - 1873-7544 (Electronic)
IS  - 0306-4522 (Linking)
VI  - 328
DP  - 2016 Jul 22
TI  - Reduced frontal cortex thickness and cortical volume associated with pathological 
      narcissism.
PG  - 50-7
LID - S0306-4522(16)30090-2 [pii]
LID - 10.1016/j.neuroscience.2016.04.025 [doi]
AB  - Pathological narcissism is often characterized by arrogant behavior, a lack of 
      empathy, and willingness to exploit other individuals. Generally, individuals 
      with high levels of narcissism are more likely to suffer mental disorders. 
      However, the brain structural basis of individual pathological narcissism trait 
      among healthy people has not yet been investigated with surface-based 
      morphometry. Thus, in this study, we investigated the relationship between 
      cortical thickness (CT), cortical volume (CV), and individual pathological 
      narcissism in a large healthy sample of 176 college students. Multiple regression 
      was used to analyze the correlation between regional CT, CV, and the total 
      Pathological Narcissism Inventory (PNI) score, adjusting for age, sex, and total 
      intracranial volume. The results showed that the PNI score was significantly 
      negatively associated with CT and CV in the right dorsolateral prefrontal cortex 
      (DLPFC, key region of the central executive network, CEN), which might be 
      associated with impaired emotion regulation processes. Furthermore, the PNI score 
      showed significant negative associations with CV in the right postcentral gyrus, 
      left medial prefrontal cortex (MPFC), and the CT in the right inferior frontal 
      cortex (IFG, overlap with social brain network), which may be related to 
      impairments in social cognition. Together, these findings suggest a unique 
      structural basis for individual differences in pathological narcissism, 
      distributed across different gray matter regions of the social brain network and 
      CEN.
CI  - Copyright (c) 2016 IBRO. Published by Elsevier Ltd. All rights reserved.
FAU - Mao, Yu
AU  - Mao Y
AD  - Key Laboratory of Cognition and Personality (SWU), Ministry of Education, 
      Chongqing 400715, China; Department of Psychology, Southwest University, 
      Chongqing 400715, China.
FAU - Sang, Na
AU  - Sang N
AD  - Key Laboratory of Cognition and Personality (SWU), Ministry of Education, 
      Chongqing 400715, China; Department of Psychology, Southwest University, 
      Chongqing 400715, China.
FAU - Wang, Yongchao
AU  - Wang Y
AD  - Key Laboratory of Cognition and Personality (SWU), Ministry of Education, 
      Chongqing 400715, China; Department of Psychology, Southwest University, 
      Chongqing 400715, China.
FAU - Hou, Xin
AU  - Hou X
AD  - Key Laboratory of Cognition and Personality (SWU), Ministry of Education, 
      Chongqing 400715, China; Department of Psychology, Southwest University, 
      Chongqing 400715, China.
FAU - Huang, Hui
AU  - Huang H
AD  - Key Laboratory of Cognition and Personality (SWU), Ministry of Education, 
      Chongqing 400715, China; Department of Psychology, Southwest University, 
      Chongqing 400715, China.
FAU - Wei, Dongtao
AU  - Wei D
AD  - Key Laboratory of Cognition and Personality (SWU), Ministry of Education, 
      Chongqing 400715, China; Department of Psychology, Southwest University, 
      Chongqing 400715, China.
FAU - Zhang, Jinfu
AU  - Zhang J
AD  - Key Laboratory of Cognition and Personality (SWU), Ministry of Education, 
      Chongqing 400715, China; Department of Psychology, Southwest University, 
      Chongqing 400715, China.
FAU - Qiu, Jiang
AU  - Qiu J
AD  - Key Laboratory of Cognition and Personality (SWU), Ministry of Education, 
      Chongqing 400715, China; Department of Psychology, Southwest University, 
      Chongqing 400715, China. Electronic address: qiuj318@swu.edu.cn.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20160427
PL  - United States
TA  - Neuroscience
JT  - Neuroscience
JID - 7605074
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Female
MH  - Frontal Lobe/*diagnostic imaging
MH  - Humans
MH  - Individuality
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - *Narcissism
MH  - Organ Size
MH  - Psychiatric Status Rating Scales
MH  - Regression Analysis
MH  - Self Concept
MH  - Self Report
MH  - Young Adult
OTO - NOTNLM
OT  - dorsolateral prefrontal cortex
OT  - inferior frontal cortex
OT  - medial prefrontal cortex
OT  - pathological narcissism
OT  - surface-based morphometry
EDAT- 2016/05/01 06:00
MHDA- 2017/07/19 06:00
CRDT- 2016/05/01 06:00
PHST- 2016/02/02 00:00 [received]
PHST- 2016/04/15 00:00 [revised]
PHST- 2016/04/15 00:00 [accepted]
PHST- 2016/05/01 06:00 [entrez]
PHST- 2016/05/01 06:00 [pubmed]
PHST- 2017/07/19 06:00 [medline]
AID - S0306-4522(16)30090-2 [pii]
AID - 10.1016/j.neuroscience.2016.04.025 [doi]
PST - ppublish
SO  - Neuroscience. 2016 Jul 22;328:50-7. doi: 10.1016/j.neuroscience.2016.04.025. Epub 
      2016 Apr 27.