PMID- 27135574
OWN - NLM
STAT- MEDLINE
DCOM- 20180321
LR  - 20180321
IS  - 1879-1026 (Electronic)
IS  - 0048-9697 (Linking)
VI  - 563-564
DP  - 2016 Sep 1
TI  - Exposure to oxychlordane is associated with shorter telomeres in arctic breeding 
      kittiwakes.
PG  - 125-30
LID - S0048-9697(16)30777-X [pii]
LID - 10.1016/j.scitotenv.2016.04.096 [doi]
AB  - Telomeres are DNA-protein complexes located at the end of chromosomes, which play 
      an important role in maintaining the genomic integrity. Telomeres shorten at each 
      cell division and previous studies have shown that telomere length is related to 
      health and lifespan and can be affected by a wide range of environmental factors. 
      Among them, some persistent organic pollutants (POPs) have the potential to 
      damage DNA. However, the effect of POPs on telomeres is poorly known for 
      wildlife. Here, we investigated the relationships between some legacy POPs 
      (organochlorine pesticides and polychlorobiphenyls) and telomere length in 
      breeding adult black-legged kittiwakes (Rissa tridactyla), an arctic seabird 
      species. Our results show that among legacy POPs, only blood concentration of 
      oxychlordane, the major metabolite of chlordane mixture, is associated with 
      shorter telomere length in females but not in males. This suggests that female 
      kittiwakes could be more sensitive to oxychlordane, potentially explaining the 
      previously reported lower survival rate in most oxychlordane-contaminated 
      kittiwakes from the same population. This study is the first to report a 
      significant and negative relationship between POPs and telomere length in a 
      free-living bird and highlights sex-related susceptibility to banned pesticides.
CI  - Copyright (c) 2016 Elsevier B.V. All rights reserved.
FAU - Blevin, Pierre
AU  - Blevin P
AD  - Centre d'Etudes Biologiques de Chize (CEBC), UMR 7372 - CNRS & Universite de la, 
      Rochelle, 79360 Villiers-en-Bois, France. Electronic address: 
      blevin.pierre@gmail.com.
FAU - Angelier, Frederic
AU  - Angelier F
AD  - Centre d'Etudes Biologiques de Chize (CEBC), UMR 7372 - CNRS & Universite de la, 
      Rochelle, 79360 Villiers-en-Bois, France.
FAU - Tartu, Sabrina
AU  - Tartu S
AD  - Centre d'Etudes Biologiques de Chize (CEBC), UMR 7372 - CNRS & Universite de la, 
      Rochelle, 79360 Villiers-en-Bois, France.
FAU - Ruault, Stephanie
AU  - Ruault S
AD  - Centre d'Etudes Biologiques de Chize (CEBC), UMR 7372 - CNRS & Universite de la, 
      Rochelle, 79360 Villiers-en-Bois, France.
FAU - Bustamante, Paco
AU  - Bustamante P
AD  - Littoral Environnement et Societes (LIENSs), UMR 7266 - CNRS & Universite de la, 
      Rochelle, 17000 La Rochelle, France.
FAU - Herzke, Dorte
AU  - Herzke D
AD  - Norwegian Institute for Air Research, NILU, Fram Centre, NO 9296 Tromso, Norway.
FAU - Moe, Borge
AU  - Moe B
AD  - Norwegian Institute for Nature Research, NINA, Hogskoleringen 9, NO 7034 
      Trondheim, Norway.
FAU - Bech, Claus
AU  - Bech C
AD  - Department of Biology, Norwegian University of Science and Technology, NO 7491, 
      Trondheim, Norway.
FAU - Gabrielsen, Geir Wing
AU  - Gabrielsen GW
AD  - Norwegian Polar Research Institute, Fram Centre, NO 9296 Tromso, Norway.
FAU - Bustnes, Jan Ove
AU  - Bustnes JO
AD  - Norwegian Institute for Nature Research, NINA, Fram Centre, NO 9296 Tromso, 
      Norway.
FAU - Chastel, Olivier
AU  - Chastel O
AD  - Centre d'Etudes Biologiques de Chize (CEBC), UMR 7372 - CNRS & Universite de la, 
      Rochelle, 79360 Villiers-en-Bois, France.
LA  - eng
PT  - Journal Article
DEP - 20160429
PL  - Netherlands
TA  - Sci Total Environ
JT  - The Science of the total environment
JID - 0330500
RN  - 0 (Insecticides)
RN  - 0 (Water Pollutants, Chemical)
RN  - 12789-03-6 (Chlordan)
RN  - 27304-13-8 (oxychlordane)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
SB  - IM
MH  - Animals
MH  - Arctic Regions
MH  - Charadriiformes/*genetics/metabolism
MH  - Chlordan/*analogs & derivatives/toxicity
MH  - Female
MH  - Insecticides/toxicity
MH  - Male
MH  - Polychlorinated Biphenyls/*toxicity
MH  - Svalbard
MH  - Telomere Shortening/*drug effects
MH  - Water Pollutants, Chemical/*toxicity
OTO - NOTNLM
OT  - Contaminants
OT  - DNA
OT  - Organochlorines
OT  - PCBs
OT  - Seabirds
OT  - Svalbard
EDAT- 2016/05/03 06:00
MHDA- 2018/03/22 06:00
CRDT- 2016/05/03 06:00
PHST- 2016/03/02 00:00 [received]
PHST- 2016/04/13 00:00 [revised]
PHST- 2016/04/13 00:00 [accepted]
PHST- 2016/05/03 06:00 [entrez]
PHST- 2016/05/03 06:00 [pubmed]
PHST- 2018/03/22 06:00 [medline]
AID - S0048-9697(16)30777-X [pii]
AID - 10.1016/j.scitotenv.2016.04.096 [doi]
PST - ppublish
SO  - Sci Total Environ. 2016 Sep 1;563-564:125-30. doi: 
      10.1016/j.scitotenv.2016.04.096. Epub 2016 Apr 29.