PMID- 27140294 OWN - NLM STAT- MEDLINE DCOM- 20170323 LR - 20181202 IS - 1724-6040 (Electronic) IS - 0391-3988 (Linking) VI - 39 IP - 5 DP - 2016 Jul 4 TI - In vitro 2D PIV measurements and related aperture areas of tricuspid bioprosthetic mitral valves at the beginning of diastole. PG - 253-7 LID - 10.5301/ijao.5000494 [doi] AB - PURPOSE: Besides ventricular parameters, the design and angular orientation of a prosthetic heart valve induce a specific flow field. The aim of this study was to know the inflow characteristics of a left ventricular model (LVM), investigating the behavior of tricuspid bioprosthetic mitral valves in terms of velocity profiles and related valve aperture areas at the beginning of diastole, under different conditions. METHODS: 3 heart rates (HRs) were established in the LVM and each mitral bioprosthesis (27 and 31 mm diameter) was installed in 2 orientations, rotated by 180 degrees . For each experimental setup, 2-dimensional particle image velocimetry (2D PIV) measurements and simultaneous mitral valve (MV) area detection were obtained from 50 samples. RESULTS: The results from the velocity profiles immediately downstream of mitral bioprostheses showed the influence of valve orientation for moderate HRs, although for a similar magnitude of mean velocity vectors. The geometries of MV open areas for each HR were similar regardless of valve orientation, except for the 27-mm valve at 90 beats per minute (bpm), and for the 31-mm valve at 60 bpm. Moreover, for each HR, similar percentages of valve open area were obtained regardless of MV nominal diameters. CONCLUSIONS: In conclusion, the experimental setup for the 2D PIV measurements synchronized with the MV area detection was a useful tool for knowing the inflow characteristics of the LVM. FAU - Bazan, Ovandir AU - Bazan O AD - Escola Politecnica of the University of Sao Paulo, Sao Paulo - Brazil. FAU - Ortiz, Jayme Pinto AU - Ortiz JP AD - Escola Politecnica of the University of Sao Paulo, Sao Paulo - Brazil. FAU - Fukumasu, Newton Kiyoshi AU - Fukumasu NK AD - Escola Politecnica of the University of Sao Paulo, Sao Paulo - Brazil. FAU - Pacifico, Antonio Luiz AU - Pacifico AL AD - Escola Politecnica of the University of Sao Paulo, Sao Paulo - Brazil. FAU - Yanagihara, Jurandir Itizo AU - Yanagihara JI AD - Escola Politecnica of the University of Sao Paulo, Sao Paulo - Brazil. LA - eng PT - Journal Article DEP - 20160425 PL - United States TA - Int J Artif Organs JT - The International journal of artificial organs JID - 7802649 SB - IM MH - *Bioprosthesis MH - Diastole/*physiology MH - *Heart Valve Prosthesis MH - Heart Ventricles/physiopathology MH - Humans MH - Mitral Valve/physiopathology MH - Models, Cardiovascular MH - Prosthesis Design MH - Rheology MH - Tricuspid Valve/physiopathology EDAT- 2016/05/04 06:00 MHDA- 2017/03/24 06:00 CRDT- 2016/05/04 06:00 PHST- 2016/04/11 00:00 [accepted] PHST- 2016/05/04 06:00 [entrez] PHST- 2016/05/04 06:00 [pubmed] PHST- 2017/03/24 06:00 [medline] AID - 0EB41F80-F3B6-46DC-A216-208E84E76E5B [pii] AID - 10.5301/ijao.5000494 [doi] PST - ppublish SO - Int J Artif Organs. 2016 Jul 4;39(5):253-7. doi: 10.5301/ijao.5000494. Epub 2016 Apr 25.