PMID- 27148823
OWN - NLM
STAT- MEDLINE
DCOM- 20170407
LR  - 20170407
IS  - 1520-5118 (Electronic)
IS  - 0021-8561 (Linking)
VI  - 64
IP  - 23
DP  - 2016 Jun 15
TI  - Ultrahigh-Performance Liquid Chromatography (UHPLC)-Tandem Mass Spectrometry 
      (MS/MS) Quantification of Nine Target Indoles in Sparkling Wines.
PG  - 4772-6
LID - 10.1021/acs.jafc.6b01254 [doi]
AB  - An ultrahigh-performance liquid chromatography (UHPLC)-tandem mass spectrometry 
      (MS/MS) method was developed for the simultaneous determination of nine target 
      indoles in sparkling wines. The proposed method requires minimal sample 
      pretreatment, and its performance parameters (accuracy, repeatability, LOD, and 
      matrix effect) indicate that it is suitable for routine analysis. Four indoles 
      were found at detectable levels in commercial Cava samples: 5-methoxytryptophol 
      (5MTL), tryptophan (TRP), tryptophan ethyl ester (TEE), and N-acetylserotonin 
      (NSER). Two of them, NSER and 5MTL, are reported here for the first time in 
      sparkling wines, with values of 0.3-2 and 0.29-29.2 mug/L, respectively. In the 
      same samples, the contents of melatonin (MEL), serotonin (SER), 
      5-hydroxytryptophan (5-OHTRP), 5-hydroxyindole-3-acetic acid (5OHIA), and 
      5-methoxy-3-indoleacetic acid (5MIA) were all below the corresponding limits of 
      detection.
FAU - Tudela, Rebeca
AU  - Tudela R
AD  - Departament de Nutricio i Bromatologia, Xarxa de Referencia en Tecnologia dels 
      Aliments (XaRTA), Institut de recerca en Nutricio i Seguretat Alimentaria (INSA), 
      Universitat de Barcelona , Campus de l'Alimentacio de Torribera, Avinguda Prat de 
      la Riba 171, 08921 Santa Coloma de Gramenet, Spain.
FAU - Ribas-Agusti, Albert
AU  - Ribas-Agusti A
AD  - IRTA-Monells , Finca Camps i Armet s/n, 17121 Monells, Spain.
FAU - Buxaderas, Susana
AU  - Buxaderas S
AD  - Departament de Nutricio i Bromatologia, Xarxa de Referencia en Tecnologia dels 
      Aliments (XaRTA), Institut de recerca en Nutricio i Seguretat Alimentaria (INSA), 
      Universitat de Barcelona , Campus de l'Alimentacio de Torribera, Avinguda Prat de 
      la Riba 171, 08921 Santa Coloma de Gramenet, Spain.
FAU - Riu-Aumatell, Montserrat
AU  - Riu-Aumatell M
AD  - Departament de Nutricio i Bromatologia, Xarxa de Referencia en Tecnologia dels 
      Aliments (XaRTA), Institut de recerca en Nutricio i Seguretat Alimentaria (INSA), 
      Universitat de Barcelona , Campus de l'Alimentacio de Torribera, Avinguda Prat de 
      la Riba 171, 08921 Santa Coloma de Gramenet, Spain.
FAU - Castellari, Massimo
AU  - Castellari M
AD  - IRTA-Monells , Finca Camps i Armet s/n, 17121 Monells, Spain.
FAU - Lopez-Tamames, Elvira
AU  - Lopez-Tamames E
AD  - Departament de Nutricio i Bromatologia, Xarxa de Referencia en Tecnologia dels 
      Aliments (XaRTA), Institut de recerca en Nutricio i Seguretat Alimentaria (INSA), 
      Universitat de Barcelona , Campus de l'Alimentacio de Torribera, Avinguda Prat de 
      la Riba 171, 08921 Santa Coloma de Gramenet, Spain.
LA  - eng
PT  - Journal Article
DEP - 20160601
PL  - United States
TA  - J Agric Food Chem
JT  - Journal of agricultural and food chemistry
JID - 0374755
RN  - 0 (Indoles)
RN  - 333DO1RDJY (Serotonin)
RN  - 712-09-4 (methoxytryptophol)
RN  - JL5DK93RCL (Melatonin)
RN  - P4TO3C82WV (N-acetylserotonin)
SB  - IM
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Food Analysis
MH  - Indoles/*analysis
MH  - Limit of Detection
MH  - Melatonin/analysis
MH  - Serotonin/analogs & derivatives/analysis
MH  - Tandem Mass Spectrometry/*methods
MH  - Wine/*analysis
OTO - NOTNLM
OT  - UHPLC-MS/MS
OT  - indole
OT  - melatonin
OT  - sparkling wine
OT  - tryptophan ethyl ester
EDAT- 2016/05/06 06:00
MHDA- 2017/04/08 06:00
CRDT- 2016/05/06 06:00
PHST- 2016/05/06 06:00 [entrez]
PHST- 2016/05/06 06:00 [pubmed]
PHST- 2017/04/08 06:00 [medline]
AID - 10.1021/acs.jafc.6b01254 [doi]
PST - ppublish
SO  - J Agric Food Chem. 2016 Jun 15;64(23):4772-6. doi: 10.1021/acs.jafc.6b01254. Epub 
      2016 Jun 1.