PMID- 27148900
OWN - NLM
STAT- MEDLINE
DCOM- 20180201
LR  - 20221207
IS  - 1873-6750 (Electronic)
IS  - 0160-4120 (Print)
IS  - 0160-4120 (Linking)
VI  - 92-93
DP  - 2016 Jul-Aug
TI  - Associations between long-term exposure to ambient particulate air pollution and 
      type 2 diabetes prevalence, blood glucose and glycosylated hemoglobin levels in 
      China.
PG  - 416-421
LID - 10.1016/j.envint.2016.03.028 [doi]
AB  - BACKGROUND: The evidence for an association between particulate air pollution and 
      type 2 diabetes mellitus (T2DM) in developing countries was very scarce. 
      OBJECTIVE: To investigate the associations of long-term exposure to fine 
      particulate matter (PM2.5) with T2DM prevalence and with fasting glucose and 
      glycosylated hemoglobin (HbA1c) levels in China. METHODS: This is a 
      cross-sectional study based on a nation-wide baseline survey of 11,847 adults who 
      participated in the China Health and Retirement Longitudinal Study from June 2011 
      to March 2012. The average residential exposure to PM2.5 for each participant in 
      the same period was estimated using a satellite-based spatial statistical model. 
      We determined the association between PM2.5 and T2DM prevalence by multivariable 
      logistic regression models. We also evaluated the association between PM2.5 and 
      fasting glucose and HbA1c levels using multivariable linear regression models. 
      Stratification analyses were conducted to explore potential effect modification. 
      RESULTS: We identified 1760 cases of T2DM, corresponding to 14.9% of the study 
      population. The average PM2.5 exposure for all participants was 72.6mug/m(3) 
      during the study period. An interquartile range increase in PM2.5 (41.1mug/m(3)) 
      was significantly associated with increased T2DM prevalence (prevalence ratio, 
      PR=1.14), and elevated levels of fasting glucose (0.26mmol/L) and HbA1c (0.08%). 
      The associations of PM2.5 with T2DM prevalence and with fasting glucose and HbA1c 
      were stronger in several subgroups. CONCLUSIONS: This nationwide cross-sectional 
      study suggested that long-term exposure to PM2.5 might increase the risk of T2DM 
      in China.
CI  - Copyright (c) 2016 Elsevier Ltd. All rights reserved.
FAU - Liu, Cong
AU  - Liu C
AD  - School of Public Health, Key Lab of Public Health Safety of the Ministry of 
      Education and Key Lab of Health Technology Assessment of the Ministry of Health, 
      Fudan University, Shanghai, China.
FAU - Yang, Changyuan
AU  - Yang C
AD  - School of Public Health, Key Lab of Public Health Safety of the Ministry of 
      Education and Key Lab of Health Technology Assessment of the Ministry of Health, 
      Fudan University, Shanghai, China.
FAU - Zhao, Yaohui
AU  - Zhao Y
AD  - National School of Development, Peking University, Beijing, China.
FAU - Ma, Zongwei
AU  - Ma Z
AD  - State Key Laboratory of Pollution Control and Resource Reuse, School of the 
      Environment, Nanjing University, Nanjing, Jiangsu Province, China.
FAU - Bi, Jun
AU  - Bi J
AD  - State Key Laboratory of Pollution Control and Resource Reuse, School of the 
      Environment, Nanjing University, Nanjing, Jiangsu Province, China.
FAU - Liu, Yang
AU  - Liu Y
AD  - Department of Environmental Health, Rollins School of Public Health, Emory 
      University, Atlanta, GA, United States.
FAU - Meng, Xia
AU  - Meng X
AD  - Department of Environmental Health, Rollins School of Public Health, Emory 
      University, Atlanta, GA, United States.
FAU - Wang, Yafeng
AU  - Wang Y
AD  - Institute for Social Science Survey, Peking University, Beijing, China.
FAU - Cai, Jing
AU  - Cai J
AD  - School of Public Health, Key Lab of Public Health Safety of the Ministry of 
      Education and Key Lab of Health Technology Assessment of the Ministry of Health, 
      Fudan University, Shanghai, China.
FAU - Chen, Renjie
AU  - Chen R
AD  - School of Public Health, Key Lab of Public Health Safety of the Ministry of 
      Education and Key Lab of Health Technology Assessment of the Ministry of Health, 
      Fudan University, Shanghai, China.
AD  - Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP), 
      Fudan University, Shanghai, China.
FAU - Kan, Haidong
AU  - Kan H
AD  - School of Public Health, Key Lab of Public Health Safety of the Ministry of 
      Education and Key Lab of Health Technology Assessment of the Ministry of Health, 
      Fudan University, Shanghai, China.
AD  - Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP), 
      Fudan University, Shanghai, China.
LA  - eng
GR  - R01 AG037031/AG/NIA NIH HHS/United States
GR  - R03 AG049144/AG/NIA NIH HHS/United States
PT  - Journal Article
DEP - 20160503
PL  - Netherlands
TA  - Environ Int
JT  - Environment international
JID - 7807270
RN  - 0 (Air Pollutants)
RN  - 0 (Blood Glucose)
RN  - 0 (Glycated Hemoglobin A)
RN  - 0 (Particulate Matter)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Air Pollutants/analysis
MH  - *Blood Glucose
MH  - China/epidemiology
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/*epidemiology/*etiology
MH  - Environmental Exposure/analysis
MH  - Female
MH  - *Glycated Hemoglobin
MH  - Humans
MH  - Longitudinal Studies
MH  - Male
MH  - Middle Aged
MH  - Particulate Matter/analysis/*toxicity
MH  - Prevalence
PMC - PMC4902714
MID - NIHMS783908
OTO - NOTNLM
OT  - *Cross-sectional study
OT  - *Fasting glucose
OT  - *Fine particulate matter
OT  - *Glycosylated hemoglobin
OT  - *Type 2 diabetes mellitus
EDAT- 2016/05/06 06:00
MHDA- 2018/02/02 06:00
PMCR- 2017/07/01
CRDT- 2016/05/06 06:00
PHST- 2016/01/15 00:00 [received]
PHST- 2016/03/20 00:00 [revised]
PHST- 2016/03/22 00:00 [accepted]
PHST- 2016/05/06 06:00 [entrez]
PHST- 2016/05/06 06:00 [pubmed]
PHST- 2018/02/02 06:00 [medline]
PHST- 2017/07/01 00:00 [pmc-release]
AID - S0160-4120(16)30108-8 [pii]
AID - 10.1016/j.envint.2016.03.028 [doi]
PST - ppublish
SO  - Environ Int. 2016 Jul-Aug;92-93:416-421. doi: 10.1016/j.envint.2016.03.028. Epub 
      2016 May 3.