PMID- 27149503
OWN - NLM
STAT- MEDLINE
DCOM- 20170202
LR  - 20220330
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 95
IP  - 18
DP  - 2016 May
TI  - Safety of Acupuncture and Pharmacopuncture in 80,523 Musculoskeletal Disorder 
      Patients: A Retrospective Review of Internal Safety Inspection and Electronic 
      Medical Records.
PG  - e3635
LID - 10.1097/MD.0000000000003635 [doi]
LID - e3635
AB  - We investigated the range and frequency of significant adverse events (AEs) in 
      use of pharmacopuncture and acupuncture using large-scale, single-center safety 
      data as evidence supporting safety of acupuncture with pharmacopuncture, used 
      extensively in Asia, is scarce. Status reports (nurse records in ambulatory and 
      inpatient care units, and administrative event records) as a part of an internal 
      audit at a Korean Medicine hospital specializing in the treatment of 
      musculoskeletal disorders, patient complaints filed through the hospital website, 
      and medical records of patients visiting from December, 2010 (inception of 
      internal audit) to October, 2014 were retrospectively reviewed. A total 80,523 
      patients (5966 inpatients and 74,557 outpatients) visited during this period. 
      Inpatients received an average 31.9 +/- 20.7 acupuncture, 23.0 +/- 15.6 
      pharmacopuncture, and 15.4 +/- 11.3 bee venom pharmacopuncture sessions, and 
      outpatients were administered 8.2 +/- 12.2 acupuncture, 7.8 +/- 11.5 
      pharmacopuncture, and 10.0 +/- 12.3 bee venom sessions, respectively. AEs 
      associated with acupuncture/pharmacopuncture were forgotten needle (n = 47), 
      hypersensitivity to bee venom (n = 37), presyncopic episode (n = 4), pneumothorax 
      (n = 4), and infection (n = 2). Most cases were mild requiring little or no 
      additional intervention and leaving no sequelae. Although serious AEs including 
      infection (n = 2) and anaphylaxis associated with bee venom treatment (n = 3) 
      were also reported, incidence was rare at 0.002% in infection and 0.019% in 
      anaphylaxis. Incidence of AEs associated with acupuncture/pharmacopuncture 
      treatment was low, and most cases were not serious. Still, however rare, 
      avoidable AEs can and should be prevented through education and corrective 
      action. Further prospective studies on the effect of error reduction strategies 
      on incidence of adverse effects are warranted.
FAU - Kim, Me-Riong
AU  - Kim MR
AD  - From the Jaseng Spine and Joint Research Institute (M-RK, J-SS, JL, YJL, Y-JA, 
      KBP, I-HH), Jaseng Medical Foundation, Seoul; and Korea Promotion Institute for 
      Traditional Medicine Industry (HDL, YL, SGK), Gyeongsan-si, Gyeongbuk, Republic 
      of Korea.
FAU - Shin, Joon-Shik
AU  - Shin JS
FAU - Lee, Jinho
AU  - Lee J
FAU - Lee, Yoon Jae
AU  - Lee YJ
FAU - Ahn, Yong-Jun
AU  - Ahn YJ
FAU - Park, Ki Byung
AU  - Park KB
FAU - Lee, Hwa Dong
AU  - Lee HD
FAU - Lee, Yoonmi
AU  - Lee Y
FAU - Kim, Sung Geun
AU  - Kim SG
FAU - Ha, In-Hyuk
AU  - Ha IH
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (Bee Venoms)
SB  - IM
MH  - Acupuncture Therapy/*adverse effects/methods
MH  - Adult
MH  - Anaphylaxis/chemically induced
MH  - Bee Venoms/*adverse effects
MH  - Drug Hypersensitivity/etiology
MH  - Electronic Health Records
MH  - Female
MH  - Humans
MH  - Inpatients/*statistics & numerical data
MH  - Male
MH  - Middle Aged
MH  - Musculoskeletal Diseases/*therapy
MH  - Needles/adverse effects
MH  - Outpatients/*statistics & numerical data
MH  - Pneumothorax/etiology
MH  - Republic of Korea
MH  - Retrospective Studies
MH  - Skin Diseases, Infectious/etiology
MH  - Syncope/etiology
PMC - PMC4863820
COIS- The authors have no conflicts of interest to disclose.
EDAT- 2016/05/07 06:00
MHDA- 2017/02/06 06:00
PMCR- 2016/05/06
CRDT- 2016/05/06 06:00
PHST- 2016/05/06 06:00 [entrez]
PHST- 2016/05/07 06:00 [pubmed]
PHST- 2017/02/06 06:00 [medline]
PHST- 2016/05/06 00:00 [pmc-release]
AID - 00005792-201605030-00068 [pii]
AID - 10.1097/MD.0000000000003635 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2016 May;95(18):e3635. doi: 10.1097/MD.0000000000003635.