PMID- 27149578 OWN - NLM STAT- MEDLINE DCOM- 20170920 LR - 20181202 IS - 1547-5069 (Electronic) IS - 1527-6546 (Linking) VI - 48 IP - 4 DP - 2016 Jul TI - Behavioral Interventions Targeting Chronic Pain, Depression, and Substance Use Disorder in Primary Care. PG - 345-53 LID - 10.1111/jnu.12213 [doi] AB - BACKGROUND: Patients with chronic pain, depression, and substance use disorder (SUD) are often treated in primary care settings. An estimated 52% of patients have a diagnosis of chronic pain, 5% to 13% have depression, and 19% have SUD. These estimates are likely low when considering the fact that 50% of primary care patients with depression and 65% with SUD are undiagnosed or do not seek help. These three conditions have overlapping neurophysiological processes, which complicate the treatment outcomes of a primary physical illness. Behavioral interventions have been widely utilized as adjunctive treatments, yet little is known about what types of behavioral interventions were effective to treat these comorbidities. This systematic review aimed to identify behavioral interventions targeting chronic pain, depression, and SUD in primary care settings. METHODS: The Cumulative Index to Nursing and Allied Health Literature, Medline, PsycInfo, and Google Scholar databases were searched to identify randomized controlled trials, using a behavioral intervention, involving adults with at least two of the three conditions. RESULTS: This search yielded 1,862 relevant records, and six articles met final selection criteria. A total of 696 participants were studied. Behavioral interventions varied in content, format, and duration. Mindfulness Oriented Recovery Enhancement (MORE), Acceptance and Commitment Therapy (ACT), Interpersonal Psychotherapy adapted for pain (IPT-P), and Cognitive Behavioral Therapy (CBT) showed promising improvements across all studies, albeit with small to moderate effects. CONCLUSIONS: MORE, ACT, and CBT combined with mindfulness and Motivational Interviewing had the most promising results for treating chronic pain, depression, and SUD in various combinations in primary care settings. CLINICAL RELEVANCE: The evidence is mounting that behavioral interventions such as mindfulness-based or cognitive-behavioral interventions are effective strategies for managing patients with comorbidities of chronic pain, depression, and SUD in primary care. Integrated delivery of behavioral interventions via group sessions, computers, and smart phones may increase patient access to treatment; save time and cost; reduce stigma, patient distress, family burden, and healthcare fragmentation; and provide a ray of hope to amplify conventional treatments. CI - (c) 2016 Sigma Theta Tau International. FAU - Barrett, Kathleen AU - Barrett K AD - Beta Omicron, Adjunct Assistant Professor, College of Health Sciences, Lienhard School of Nursing, Pace University, Pleasantville, NY, USA. FAU - Chang, Yu-Ping AU - Chang YP AD - Gamma Kappa, Associate Professor, School of Nursing, The State University of New York at Buffalo, Buffalo, NY, USA. LA - eng PT - Journal Article PT - Review PT - Systematic Review DEP - 20160505 PL - United States TA - J Nurs Scholarsh JT - Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing JID - 100911591 SB - IM MH - Behavior Therapy/*methods MH - Chronic Pain/epidemiology/*therapy MH - Comorbidity MH - Depression/epidemiology/*therapy MH - Humans MH - *Primary Health Care MH - Randomized Controlled Trials as Topic MH - Substance-Related Disorders/epidemiology/*therapy MH - Treatment Outcome OTO - NOTNLM OT - Behavioral interventions OT - chronic pain OT - depression OT - primary care OT - substance use disorders EDAT- 2016/05/06 06:00 MHDA- 2017/09/21 06:00 CRDT- 2016/05/06 06:00 PHST- 2016/03/07 00:00 [accepted] PHST- 2016/05/06 06:00 [entrez] PHST- 2016/05/06 06:00 [pubmed] PHST- 2017/09/21 06:00 [medline] AID - 10.1111/jnu.12213 [doi] PST - ppublish SO - J Nurs Scholarsh. 2016 Jul;48(4):345-53. doi: 10.1111/jnu.12213. Epub 2016 May 5.