PMID- 27153810 OWN - NLM STAT- MEDLINE DCOM- 20161213 LR - 20181113 IS - 1471-244X (Electronic) IS - 1471-244X (Linking) VI - 16 DP - 2016 May 6 TI - A case of malignant catatonia with idiopathic pulmonary arterial hypertension treated by electroconvulsive therapy. PG - 130 LID - 10.1186/s12888-016-0835-4 [doi] LID - 130 AB - BACKGROUND: Idiopathic pulmonary arterial hypertension (IPAH) is a progressive and fatal cardiovascular disease if left untreated. In patients with IPAH with psychiatric illness or other complications, careful attention is required when administering medical therapies that may affect their hemodynamics. Patients suffering from IPAH who undergo anesthesia and surgery have a high mortality and morbidity rate. We describe the treatment of intractable psychiatric symptoms with electroconvulsive therapy (ECT) in a patient with IPAH. CASE PRESENTATION: A 23-year-old woman with IPAH and type I diabetes mellitus (DM) presented with malignant catatonia. Her heart function was classified as New York Heart Association (NYHA) class III. She required a rapid cure and ECT due to various psychiatric symptoms resistant to conventional medications. Pulmonary hypertensive (PH) crisis is the most concerning complication that can be induced by the sympathetic stimulation of ECT. To avoid PH crisis, we administered oxygen using a laryngeal mask and administered remifentanil for anesthesia. We also prepared standby nitric oxide for possible PH crisis, although it was ultimately not needed. With 14 ECT sessions, her malignant catatonia was ameliorated without physical complications. CONCLUSION: ECT is an acceptable option for the treatment of medication-refractory psychiatric disturbances in patients with IPAH, provided careful management is assured to prevent or address complications. FAU - Hobo, Mizue AU - Hobo M AD - Department of Psychiatry and Behavioral Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan. AD - Clinical Center for Pleasant Sleep, Medical Hospital, Tokyo Medical and Dental University, Tokyo, Japan. FAU - Uezato, Akihito AU - Uezato A AD - Department of Psychiatry and Behavioral Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan. AD - Clinical Center for Pleasant Sleep, Medical Hospital, Tokyo Medical and Dental University, Tokyo, Japan. FAU - Nishiyama, Mitsunori AU - Nishiyama M AD - Department of Pediatrics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan. FAU - Suzuki, Mayumi AU - Suzuki M AD - Department of Anesthesiology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan. FAU - Kurata, Jiro AU - Kurata J AD - Department of Anesthesiology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan. FAU - Makita, Koshi AU - Makita K AD - Department of Anesthesiology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan. FAU - Yamamoto, Naoki AU - Yamamoto N AD - Department of Psychiatry and Behavioral Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan. FAU - Nishikawa, Toru AU - Nishikawa T AD - Department of Psychiatry and Behavioral Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan. tnis.psyc@tmd.ac.jp. LA - eng PT - Case Reports PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20160506 PL - England TA - BMC Psychiatry JT - BMC psychiatry JID - 100968559 SB - IM MH - Catatonia/complications/*therapy MH - Electroconvulsive Therapy/*methods MH - Familial Primary Pulmonary Hypertension/complications/*therapy MH - Female MH - Humans MH - Young Adult PMC - PMC4859975 OTO - NOTNLM OT - Electroconvulsive therapy OT - Idiopathic pulmonary arterial hypertension OT - Malignant catatonia OT - Pulmonary hypertensive crisis OT - Remifentanil EDAT- 2016/05/08 06:00 MHDA- 2016/12/15 06:00 PMCR- 2016/05/06 CRDT- 2016/05/08 06:00 PHST- 2015/08/10 00:00 [received] PHST- 2016/04/27 00:00 [accepted] PHST- 2016/05/08 06:00 [entrez] PHST- 2016/05/08 06:00 [pubmed] PHST- 2016/12/15 06:00 [medline] PHST- 2016/05/06 00:00 [pmc-release] AID - 10.1186/s12888-016-0835-4 [pii] AID - 835 [pii] AID - 10.1186/s12888-016-0835-4 [doi] PST - epublish SO - BMC Psychiatry. 2016 May 6;16:130. doi: 10.1186/s12888-016-0835-4.