PMID- 27160098
OWN - NLM
STAT- MEDLINE
DCOM- 20180503
LR  - 20181202
IS  - 1432-1971 (Electronic)
IS  - 0172-0643 (Linking)
VI  - 37
IP  - 6
DP  - 2016 Aug
TI  - Intermediate-Term Results After Extracardiac Conduit Fontan Palliation in 
      Children and Young Adults with Single Ventricle Physiology-A Single-center 
      Experience.
PG  - 1111-8
LID - 10.1007/s00246-016-1402-y [doi]
AB  - The Fontan operation and its modifications are currently the standard palliation 
      in patients with single ventricle physiology. The advantages of extracardiac 
      conduit Fontan operation (ECF) have previously been described. We evaluated the 
      outcome of patients who underwent ECF operation at our center since the year 2000 
      to assess morbidity, mortality and New York Heart Association (NYHA) functional 
      class in the current era. Medical records of 97 patients who underwent ECF 
      operation from November 2000 till October 2013 were reviewed to determine the 
      diagnosis, age at surgery, surgical technique, postoperative complications, NYHA 
      class at last follow-up, echocardiographic parameters, and most recent Holter 
      monitor results. The median age at surgery was 3.4 years with 4 total deaths 
      until last follow-up (hospital mortality was 1 %, and mortality after hospital 
      discharge was 3 %). Seventy-eight of the 97 patients (80 %) underwent fenestrated 
      Fontan surgery. Median duration of follow-up was 3.9 years (IQR 0.2-12.2 years). 
      At the latest follow-up, 62 patients (67 %) were determined to be in NYHA class 
      I, 25 patients (27 %) in NYHA class II, and 6 (6 %) patients in NYHA class III, 
      and the median oxygen saturation was 92 % (IQR 86-96). There were 15 patients 
      with history of preoperative arrhythmias and 6 of them required pacemaker 
      placement at the time of surgery. One patient developed ectopic atrial 
      tachycardia, and 1 patient had clinical thromboembolism on follow-up. Systolic 
      function of the single ventricle by transthoracic echocardiogram at the latest 
      follow-up was described as normal in 77 patients (83 %), fair in 15 patients 
      (16 %), and poor in 1 patient (1 %). The results of our study show that patients 
      who undergo extracardiac conduit Fontan operation in the modern era may have 
      significantly less morbidity and mortality when compared to earlier years.
FAU - Raj, Shashi
AU  - Raj S
AD  - Division of Cardiology, Department of Pediatrics, Children's Heart Center, Holtz 
      Children's Hospital at the University of Miami, Miller School of Medicine/Jackson 
      Memorial Medical Center, 1611 NW 12th Avenue, P.O Box 016960 (R-76), Miami, FL, 
      33101, USA. shashi-raj@uiowa.edu.
FAU - Rosenkranz, Eliot
AU  - Rosenkranz E
AD  - Division of Pediatric Cardiothoracic Surgery, Department of Surgery, Children's 
      Heart Center, Holtz Children's Hospital at the University of Miami, Miller School 
      of Medicine/Jackson Memorial Medical Center, Miami, FL, USA.
FAU - Sears, Barbara
AU  - Sears B
AD  - Division of Pediatric Cardiothoracic Surgery, Department of Surgery, Children's 
      Heart Center, Holtz Children's Hospital at the University of Miami, Miller School 
      of Medicine/Jackson Memorial Medical Center, Miami, FL, USA.
FAU - Swaminathan, Sethuraman
AU  - Swaminathan S
AD  - Division of Cardiology, Department of Pediatrics, Children's Heart Center, Holtz 
      Children's Hospital at the University of Miami, Miller School of Medicine/Jackson 
      Memorial Medical Center, 1611 NW 12th Avenue, P.O Box 016960 (R-76), Miami, FL, 
      33101, USA.
LA  - eng
PT  - Journal Article
DEP - 20160509
PL  - United States
TA  - Pediatr Cardiol
JT  - Pediatric cardiology
JID - 8003849
SB  - IM
MH  - Adolescent
MH  - Arrhythmias, Cardiac
MH  - Child
MH  - Child, Preschool
MH  - Follow-Up Studies
MH  - Fontan Procedure
MH  - Heart Defects, Congenital
MH  - *Heart Ventricles
MH  - Humans
MH  - Treatment Outcome
MH  - Young Adult
OTO - NOTNLM
OT  - Extracardiac conduit
OT  - Fontan
OT  - Protein-losing enteropathy
OT  - Single ventricle
EDAT- 2016/05/11 06:00
MHDA- 2018/05/04 06:00
CRDT- 2016/05/11 06:00
PHST- 2015/12/08 00:00 [received]
PHST- 2016/04/21 00:00 [accepted]
PHST- 2016/05/11 06:00 [entrez]
PHST- 2016/05/11 06:00 [pubmed]
PHST- 2018/05/04 06:00 [medline]
AID - 10.1007/s00246-016-1402-y [pii]
AID - 10.1007/s00246-016-1402-y [doi]
PST - ppublish
SO  - Pediatr Cardiol. 2016 Aug;37(6):1111-8. doi: 10.1007/s00246-016-1402-y. Epub 2016 
      May 9.