PMID- 27168710
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160512
LR  - 20200930
IS  - 0971-5851 (Print)
IS  - 0975-2129 (Electronic)
IS  - 0971-5851 (Linking)
VI  - 37
IP  - 2
DP  - 2016 Apr-Jun
TI  - Adjuvant brachytherapy for Stage IB Grade 2 endometrial carcinoma: Multivariate 
      analysis of a single institution experience.
PG  - 112-5
LID - 10.4103/0971-5851.180148 [doi]
AB  - OBJECTIVE: The aim was to investigate the value of postoperative brachytherapy 
      for patients with Stage IB, Grade 2 endometrial carcinoma. PATIENTS AND METHODS: 
      Forty-six patients with Stage IB, Grade 2 endometrial carcinoma, were treated 
      with simple hysterectomy and bilateral oophorectomy in our institution. The mean 
      age was 63 (range, 42-81). Surgical staging, defined as peritoneal washing and 
      pelvic lymph node sampling was performed in 73% of patients. Twenty-two patients 
      (47%) received a postoperative intravaginal brachytherapy (IVRT), and 24 patients 
      (53%) were followed-up without additional treatment. RESULTS: The median 
      follow-up was 60 months. The 5-year overall survival for irradiated and 
      nonirradiated patients, was 83.5 and 94.7%, respectively. Four patients (8.7%) 
      developed relapse, two in the group of postoperative IVRT and 2 in the follow-up 
      only group. Multivariate analysis demonstrated a borderline association (P = 
      0.06) between lower uterine segment involvement and poor pelvic-vaginal control. 
      The presence of GOG #99 high-risk features did not affect the pelvic control 
      rate. CONCLUSION: According to our experience and previously published data, most 
      patients with FIGO Stage IB, Grade 2 endometrial carcinoma may be cured with 
      surgery alone.
FAU - Tokar, Margarita
AU  - Tokar M
AD  - Department of Oncology, Faculty of Health Sciences, Soroka University Medical 
      Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
FAU - Meirovich, Michael
AU  - Meirovich M
AD  - Division of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka 
      University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, 
      Israel.
FAU - Bobilev, Dmitri
AU  - Bobilev D
AD  - Department of Oncology, Faculty of Health Sciences, Soroka University Medical 
      Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
FAU - Mermershtain, Wilmosh
AU  - Mermershtain W
AD  - Department of Oncology, Faculty of Health Sciences, Soroka University Medical 
      Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Indian J Med Paediatr Oncol
JT  - Indian journal of medical and paediatric oncology : official journal of Indian 
      Society of Medical & Paediatric Oncology
JID - 9604571
PMC - PMC4854042
OTO - NOTNLM
OT  - Adjuvant brachytherapy
OT  - endometrial adenocarcinoma
OT  - endometrium
OT  - radiotherapy
EDAT- 2016/05/12 06:00
MHDA- 2016/05/12 06:01
PMCR- 2016/04/01
CRDT- 2016/05/12 06:00
PHST- 2016/05/12 06:00 [entrez]
PHST- 2016/05/12 06:00 [pubmed]
PHST- 2016/05/12 06:01 [medline]
PHST- 2016/04/01 00:00 [pmc-release]
AID - IJMPO-37-112 [pii]
AID - 10.4103/0971-5851.180148 [doi]
PST - ppublish
SO  - Indian J Med Paediatr Oncol. 2016 Apr-Jun;37(2):112-5. doi: 
      10.4103/0971-5851.180148.