PMID- 27169934
OWN - NLM
STAT- MEDLINE
DCOM- 20170612
LR  - 20220317
IS  - 1435-702X (Electronic)
IS  - 0721-832X (Linking)
VI  - 254
IP  - 11
DP  - 2016 Nov
TI  - Relationship between metamorphopsia and foveal microstructure in patients with 
      branch retinal vein occlusion and cystoid macular edema.
PG  - 2191-2196
AB  - PURPOSE: We aimed to investigate the relationship between the severity of 
      metamorphopsia and the foveal microstructure measured with spectral-domain 
      optical coherence tomography (SD-OCT) in patients with cystoid macular edema 
      caused by branch retinal vein occlusion (BRVO-CME). METHODS: The study included 
      30 eyes of 30 patients with BRVO-CME. We examined visual acuity and the severity 
      of metamorphopsia using M-CHARTS. Central foveal thickness, central retinal 
      thickness at the fovea (CRT-1 mm), and macular volume were measured with SD-OCT 
      software. The status of ellipsoid zone (EZ), external limiting membrane (ELM), 
      outer retinal cyst, and inner retinal cyst was also evaluated. RESULTS: The mean 
      metamorphopsia score was 0.77 +/- 0.50, with 28 of 30 patients (93 %) having 
      metamorphopsia (metamorphopsia score >/= 0.2). The vertical metamorphopsia score 
      (0.89 +/- 0.54) was significantly higher than the horizontal metamorphopsia score 
      (0.64 +/- 0.53) (p < 0.005). The status of EZ and ELM was significantly associated 
      with visual acuity, but not with the mean metamorphopsia score. The mean 
      metamorphopsia score was significantly related to CRT-1 mm (p < 0.05) and the 
      presence of inner retinal cyst (p < 0.05). CONCLUSIONS: The severity of 
      metamorphopsia was significantly associated with central retinal thickness and 
      the presence of inner retinal cyst.
FAU - Murakami, Tomoya
AU  - Murakami T
AD  - Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 
      Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan.
FAU - Okamoto, Fumiki
AU  - Okamoto F
AD  - Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 
      Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan. Fumiki-o@md.tsukuba.ac.jp.
FAU - Iida, Masaharu
AU  - Iida M
AD  - Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 
      Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan.
FAU - Sugiura, Yoshimi
AU  - Sugiura Y
AD  - Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 
      Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan.
FAU - Okamoto, Yoshifumi
AU  - Okamoto Y
AD  - Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 
      Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan.
FAU - Hiraoka, Takahiro
AU  - Hiraoka T
AD  - Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 
      Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan.
FAU - Oshika, Tetsuro
AU  - Oshika T
AD  - Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 
      Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan.
LA  - eng
PT  - Journal Article
DEP - 20160512
PL  - Germany
TA  - Graefes Arch Clin Exp Ophthalmol
JT  - Graefe's archive for clinical and experimental ophthalmology = Albrecht von 
      Graefes Archiv fur klinische und experimentelle Ophthalmologie
JID - 8205248
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Female
MH  - Fluorescein Angiography
MH  - Follow-Up Studies
MH  - Fovea Centralis/*pathology
MH  - Fundus Oculi
MH  - Humans
MH  - Macular Edema/*complications/diagnosis/physiopathology
MH  - Male
MH  - Middle Aged
MH  - Retinal Vein Occlusion/*complications/diagnosis
MH  - Retrospective Studies
MH  - Severity of Illness Index
MH  - Tomography, Optical Coherence/*methods
MH  - Vision Disorders/diagnosis/*etiology/physiopathology
MH  - *Visual Acuity
OTO - NOTNLM
OT  - Branch retinal vein occlusion
OT  - Cystoid macular edema
OT  - Metamorphopsia
OT  - Optical coherence tomography
EDAT- 2016/10/27 06:00
MHDA- 2017/06/13 06:00
CRDT- 2016/05/13 06:00
PHST- 2016/02/25 00:00 [received]
PHST- 2016/05/03 00:00 [accepted]
PHST- 2016/04/29 00:00 [revised]
PHST- 2016/10/27 06:00 [pubmed]
PHST- 2017/06/13 06:00 [medline]
PHST- 2016/05/13 06:00 [entrez]
AID - 10.1007/s00417-016-3382-2 [pii]
AID - 10.1007/s00417-016-3382-2 [doi]
PST - ppublish
SO  - Graefes Arch Clin Exp Ophthalmol. 2016 Nov;254(11):2191-2196. doi: 
      10.1007/s00417-016-3382-2. Epub 2016 May 12.