PMID- 27170351
OWN - NLM
STAT- MEDLINE
DCOM- 20170227
LR  - 20181113
IS  - 1993-0402 (Electronic)
IS  - 1672-0415 (Linking)
VI  - 22
IP  - 12
DP  - 2016 Dec
TI  - Efficacy and safety of Qiaoshao Formula () on patients with lifelong premature 
      ejaculation of Gan (Liver) depression and Shen (Kidney) deficiency syndrome: A 
      randomized controlled trial.
PG  - 889-893
AB  - OBJECTIVE: To observe the effificacy and safety of Qiaoshao Formula (, QSF) on 
      patients with lifelong premature ejaculation (LPE) of Gan (Liver) depression and 
      Shen (Kidney) defificiency syndrome. METHODS: A total of 60 LPE patients were 
      randomly divided into treatment (QSF) and control (dapoxetine) groups. The 
      treatment group received QSF twice a day and the control group received 
      dapoxetine 1 to 2 h prior to planned sexual intercourse for 4 weeks. The outcomes 
      included intra-vaginal ejaculation latency time (IELT), premature ejaculation 
      diagnostic tool (PEDT), clinical global impression of change (CGIC), scores of 
      Chinese medicine symptoms (CMSS), sex life satisfaction (SLS) and adverse events 
      (AEs). RESULTS: In the treated group, the median IELT was 3 min vs. 1.5 min 
      before and after treatment (P<0.05). PEDT in the treated group was reduced to 
      11.76+/-1.68 from 15.83+/-2.30 after treatment (P<0.05). Besides, patient's SLS was 
      improved from 1.30+/-0.05 to 6.30+/-0.04 (P<0.05), and spouse's SLS was increased 
      from 1.30+/-0.to 6.10+/-0.06 (P<0.05); CMSS was decrease from 14.86+/-3.02 to 9.62+/-2.87 
      (P<0.05). In addition, no significant AE was observed in both groups. CONCLUSION: 
      QSF may be effective and safe on LPE patients with Gan depression and Shen 
      defificiency syndrome.
FAU - Guo, Jun
AU  - Guo J
AD  - Department of Andrology, Xiyuan Hospital, China Academy of Chinese Medical 
      Sciences, Beijing, 100091, China.
FAU - Gao, Qing-He
AU  - Gao QH
AD  - Department of Andrology, Xiyuan Hospital, China Academy of Chinese Medical 
      Sciences, Beijing, 100091, China.
FAU - Wang, Fu
AU  - Wang F
AD  - Department of Andrology, Xiyuan Hospital, China Academy of Chinese Medical 
      Sciences, Beijing, 100091, China. fu311306@163.com.
FAU - Yu, Guo-Jin
AU  - Yu GJ
AD  - Department of Andrology, Xiyuan Hospital, China Academy of Chinese Medical 
      Sciences, Beijing, 100091, China.
FAU - Zhang, Ji-Wei
AU  - Zhang JW
AD  - Department of Andrology, Xiyuan Hospital, China Academy of Chinese Medical 
      Sciences, Beijing, 100091, China.
FAU - Zeng, Yin
AU  - Zeng Y
AD  - Department of Andrology, Xiyuan Hospital, China Academy of Chinese Medical 
      Sciences, Beijing, 100091, China.
FAU - Geng, Qiang
AU  - Geng Q
AD  - Department of Andrology, The First Teaching Hospital of Tianjin University of 
      Traditional Chinese Medicine, Tianjin, 300193, China.
FAU - Guo, Bo-da
AU  - Guo BD
AD  - Xiangya School of Medicine, Central South University, Changsha, 410013, China.
FAU - Han, Qiang
AU  - Han Q
AD  - Department of Andrology, Beijing Traditional Chinese Medicine Hospital 
      Affilliated to Capital Medical University, Beijing, 100010, China.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20160512
PL  - China
TA  - Chin J Integr Med
JT  - Chinese journal of integrative medicine
JID - 101181180
RN  - 0 (Drugs, Chinese Herbal)
SB  - IM
MH  - Adult
MH  - Drugs, Chinese Herbal/adverse effects/*therapeutic use
MH  - Humans
MH  - Kidney/*pathology
MH  - Liver/*pathology
MH  - Male
MH  - Middle Aged
MH  - Personal Satisfaction
MH  - Premature Ejaculation/diagnosis/*drug therapy
MH  - Syndrome
MH  - Time Factors
MH  - Treatment Outcome
MH  - Young Adult
OTO - NOTNLM
OT  - Chinese medicine
OT  - Qiaoshao Formula
OT  - dapoxetine
OT  - intra-vaginal ejaculation latency time
OT  - lifelong premature ejaculation
OT  - premature ejaculation diagnostic tool
EDAT- 2016/05/14 06:00
MHDA- 2017/02/28 06:00
CRDT- 2016/05/13 06:00
PHST- 2015/07/06 00:00 [received]
PHST- 2016/05/14 06:00 [pubmed]
PHST- 2017/02/28 06:00 [medline]
PHST- 2016/05/13 06:00 [entrez]
AID - 10.1007/s11655-016-2456-7 [pii]
AID - 10.1007/s11655-016-2456-7 [doi]
PST - ppublish
SO  - Chin J Integr Med. 2016 Dec;22(12):889-893. doi: 10.1007/s11655-016-2456-7. Epub 
      2016 May 12.