PMID- 27186185
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160517
LR  - 20220410
IS  - 1734-1922 (Print)
IS  - 1896-9151 (Electronic)
IS  - 1734-1922 (Linking)
VI  - 12
IP  - 2
DP  - 2016 Apr 1
TI  - Evaluation of sural nerve automated nerve conduction study in the diagnosis of 
      peripheral neuropathy in patients with type 2 diabetes mellitus.
PG  - 390-3
LID - 10.5114/aoms.2016.59265 [doi]
AB  - INTRODUCTION: New tests for improved diagnosis of diabetic peripheral neuropathy 
      (DPN) are useful. MATERIAL AND METHODS: We evaluated the utility of automated 
      nerve conduction study (NCS) of the sural nerve with a new portable device for 
      the diagnosis of DPN in patients with type 2 diabetes mellitus (T2DM). This study 
      included 114 T2DM patients (58 men) with mean age 64.60 +/-8.61 years. Exclusion 
      criteria were B12 depletion, alcohol abuse and other causes of peripheral 
      neuropathy. The reference method was the Neuropathy Disability Score (NDS) with a 
      threshold NDS >/= 3. Sural nerve automated NCS was carried out with the portable 
      NC-stat DPNCheck device. Sensory nerve conduction velocity and sensory nerve 
      action potential amplitude were measured bilaterally. Automated NCS was 
      considered abnormal when >/= 1 of the two aforementioned neurophysiological 
      parameters was abnormal in at least one leg. RESULTS: Examination with NC-stat 
      DPNCheck exhibited 90.48% sensitivity, 86.11% specificity, 79.17% positive 
      predictive value (PPV) and 93.94% negative predictive value (NPV). The positive 
      likelihood ratio (LR+) was 6.51 and the negative likelihood ratio (LR-) was 0.11. 
      CONCLUSIONS: Sural nerve automated NCS with the NC-stat DPNCheck device exhibits 
      high sensitivity and specificity for the diagnosis of DPN in T2DM.
FAU - Chatzikosma, Georgia
AU  - Chatzikosma G
AD  - Diabetes Centre, Second Department of Internal Medicine, Democritus University of 
      Thrace, Alexandroupolis, Greece.
FAU - Pafili, Kalliopi
AU  - Pafili K
AD  - Diabetes Centre, Second Department of Internal Medicine, Democritus University of 
      Thrace, Alexandroupolis, Greece.
FAU - Demetriou, Maria
AU  - Demetriou M
AD  - Diabetes Centre, Second Department of Internal Medicine, Democritus University of 
      Thrace, Alexandroupolis, Greece.
FAU - Vadikolias, Konstantinos
AU  - Vadikolias K
AD  - Diabetes Centre, Second Department of Internal Medicine, Democritus University of 
      Thrace, Alexandroupolis, Greece.
FAU - Maltezos, Efstratios
AU  - Maltezos E
AD  - Diabetes Centre, Second Department of Internal Medicine, Democritus University of 
      Thrace, Alexandroupolis, Greece.
FAU - Papanas, Nikolaos
AU  - Papanas N
AD  - Diabetes Centre, Second Department of Internal Medicine, Democritus University of 
      Thrace, Alexandroupolis, Greece.
LA  - eng
PT  - Journal Article
DEP - 20160412
PL  - Poland
TA  - Arch Med Sci
JT  - Archives of medical science : AMS
JID - 101258257
PMC - PMC4848369
OTO - NOTNLM
OT  - diabetes mellitus
OT  - diabetic neuropathy
OT  - diagnosis
OT  - nerve conduction study
EDAT- 2016/05/18 06:00
MHDA- 2016/05/18 06:01
PMCR- 2016/04/01
CRDT- 2016/05/18 06:00
PHST- 2014/08/05 00:00 [received]
PHST- 2014/09/03 00:00 [accepted]
PHST- 2016/05/18 06:00 [entrez]
PHST- 2016/05/18 06:00 [pubmed]
PHST- 2016/05/18 06:01 [medline]
PHST- 2016/04/01 00:00 [pmc-release]
AID - 27370 [pii]
AID - 10.5114/aoms.2016.59265 [doi]
PST - ppublish
SO  - Arch Med Sci. 2016 Apr 1;12(2):390-3. doi: 10.5114/aoms.2016.59265. Epub 2016 Apr 
      12.