PMID- 27190420
OWN - PIP
STAT- PubMed-not-MEDLINE
DCOM- 20160518
LR  - 20200930
IS  - 2589-0557 (Print)
IS  - 2589-0565 (Electronic)
IS  - 2589-0557 (Linking)
VI  - 37
IP  - 1
DP  - 2016 Jan-Jun
TI  - Erythema elevatum diutinum in acquired immune deficiency syndrome: Can it be an 
      immune reconstitution inflammatory syndrome?
PG  - 81-4
LID - 10.4103/0253-7184.180287 [doi]
AB  - A 47-year-old male with acquired immune deficiency syndrome (AIDS) presented with 
      multiple hyperpigmented papules and nodules on both ankles, dorsum of bilateral 
      feet and soles. It was associated with mild itching and pain. The patient was 
      diagnosed with human immunodeficiency virus (HIV) in 2007. First-line 
      antiretroviral therapy (ART) was started in 2009 to which he responded initially. 
      He was shifted to second-line ART 11 months ago in March 2015 due to treatment 
      failure as suggested by CD4 count of 50 cells/mm(3). The present skin lesions 
      started 2 months after the initiation of second-line ART. Differential diagnoses 
      considered were Kaposi's sarcoma and immune reconstitution inflammatory syndrome 
      (IRIS) related infections, but biopsy was suggestive of erythema elevatum 
      diutinum (EED). Patient was started on oral dapsone 100 mg/day and increased to 
      200 mg/day to which he is responding gradually. In the present case, appearance 
      of the lesions after initiation of second-line ART coupled with increase in CD4 
      count and decrease of viral load below undetectable level suggest that EED could 
      be an IRIS.
FAU - Jose, Sheethal K
AU  - Jose SK
AD  - Department of Skin-VD, SSG Hospital, Vadodara, Gujarat, India.
FAU - Marfatia, Yogesh S
AU  - Marfatia YS
AD  - Department of Skin-VD, SSG Hospital, Vadodara, Gujarat, India.
LA  - eng
PT  - Case Reports
PL  - India
TA  - Indian J Sex Transm Dis AIDS
JT  - Indian journal of sexually transmitted diseases and AIDS
JID - 101730896
PMC - PMC4857691
OTO - NOTNLM
OT  - EED
OT  - HIV/AIDS
OT  - IRIS
EDAT- 2016/05/18 06:00
MHDA- 2016/05/18 06:01
PMCR- 2016/01/01
CRDT- 2016/05/19 06:00
PHST- 2016/05/19 06:00 [entrez]
PHST- 2016/05/18 06:00 [pubmed]
PHST- 2016/05/18 06:01 [medline]
PHST- 2016/01/01 00:00 [pmc-release]
AID - IJSTD-37-81 [pii]
AID - 10.4103/0253-7184.180287 [doi]
PST - ppublish
SO  - Indian J Sex Transm Dis AIDS. 2016 Jan-Jun;37(1):81-4. doi: 
      10.4103/0253-7184.180287.