PMID- 27190637 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20160518 LR - 20200930 IS - 2090-004X (Print) IS - 2090-0058 (Electronic) IS - 2090-004X (Linking) VI - 2016 DP - 2016 TI - Multimodal Image Analysis in Acquired Vitelliform Lesions and Adult-Onset Foveomacular Vitelliform Dystrophy. PG - 6037537 LID - 10.1155/2016/6037537 [doi] LID - 6037537 AB - Purpose. To characterize vitelliform lesions (VLs) in adult-onset foveomacular vitelliform dystrophy (AOFVD) and acquired vitelliform (AVL) patients using multimodal image analysis. Methods. Retrospective study of twenty-eight eyes from nineteen patients diagnosed with AVL or AOFVD. They were evaluated by color fundus photographs, fundus autofluorescence (FAF), fluorescein angiography (FA), and spectral-domain optical coherence tomography (SD-OCT). Results. Bilateral VLs were associated with AOFVD (p = 0.013). Regular and centered VLs were associated with AOFVD (p = 0.004 and p = 0.016), whereas irregular and noncentered lesions were more frequent in AVL patients. Visual acuity, greatest linear dimension (GLD), lesion height (LH), and pseudohypopyon were similar between groups. Whereas median LH and GLD in AVL group diminished significantly during follow-up (p = 0.009 and p = 0.001), AOFVD lesions tended to become larger and thicker. Conclusions. When consulting a patient presenting a VL with unknown age of onset, familial history, or previous retinal diseases, some aspects of multimodal imaging assessment may lead the ophthalmologist to a correct diagnosis. FAU - Rocha Bastos, Ricardo AU - Rocha Bastos R AD - Department of Ophthalmology, Hospital Sao Joao, Porto, Portugal. FAU - Ferreira, Carla Sofia AU - Ferreira CS AD - Department of Ophthalmology, Hospital Sao Joao, Porto, Portugal. FAU - Brandao, Elisete AU - Brandao E AD - Department of Ophthalmology, Hospital Sao Joao, Porto, Portugal. FAU - Falcao-Reis, Fernando AU - Falcao-Reis F AD - Department of Ophthalmology, Hospital Sao Joao, Porto, Portugal; Department of Sense Organs, Faculty of Medicine, University of Porto, Portugal. FAU - Carneiro, Angela M AU - Carneiro AM AD - Department of Ophthalmology, Hospital Sao Joao, Porto, Portugal; Department of Sense Organs, Faculty of Medicine, University of Porto, Portugal. LA - eng PT - Journal Article DEP - 20160412 PL - United States TA - J Ophthalmol JT - Journal of ophthalmology JID - 101524199 PMC - PMC4844885 EDAT- 2016/05/18 06:00 MHDA- 2016/05/18 06:01 PMCR- 2016/04/12 CRDT- 2016/05/19 06:00 PHST- 2015/11/05 00:00 [received] PHST- 2016/02/24 00:00 [revised] PHST- 2016/03/17 00:00 [accepted] PHST- 2016/05/19 06:00 [entrez] PHST- 2016/05/18 06:00 [pubmed] PHST- 2016/05/18 06:01 [medline] PHST- 2016/04/12 00:00 [pmc-release] AID - 10.1155/2016/6037537 [doi] PST - ppublish SO - J Ophthalmol. 2016;2016:6037537. doi: 10.1155/2016/6037537. Epub 2016 Apr 12.