PMID- 27210091
OWN - NLM
STAT- MEDLINE
DCOM- 20160721
LR  - 20160523
IS  - 0385-0684 (Print)
IS  - 0385-0684 (Linking)
VI  - 43
IP  - 5
DP  - 2016 May
TI  - [Intraoperative BCNU Wafer Implantation for High-Grade Glioma--A Questionnaire 
      Targeting Japanese Neurosurgeons].
PG  - 603-7
AB  - Carmustine (BCNU) wafer implantation has been used in Japanese patients after 
      resection of high-grade glioma (HGG) since 2013. Wafer implantation plays an 
      important role in improving the prognosis of HGG patients, but it often causes 
      particular changes as observed on neuroimaging and various adverse effects (AEs). 
      Here, we conducted a questionnaire-based survey of Japanese neurosurgeons to 
      determine how they feel about this treatment based on their actual observations. 
      Most neurosurgeons had a positive impression of the treatment based on previous 
      evidence of clinical effectiveness. Additionally, we found that the Japanese 
      neurosurgeons are taking measures to cope with some AEs including cerebral edema, 
      postoperative convulsions, cerebrospinal fluid leakage, and protracted wound 
      healing.
FAU - Ishikawa, Eiichi
AU  - Ishikawa E
AD  - Dept. of Neurosurgery, University of Tsukuba.
FAU - Yamamoto, Tetsuya
AU  - Yamamoto T
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Gan To Kagaku Ryoho
JT  - Gan to kagaku ryoho. Cancer & chemotherapy
JID - 7810034
RN  - 0 (Antineoplastic Agents, Alkylating)
RN  - U68WG3173Y (Carmustine)
SB  - IM
MH  - Antineoplastic Agents, Alkylating/administration & dosage/adverse 
      effects/*therapeutic use
MH  - Brain Neoplasms/*drug therapy/surgery
MH  - Carmustine/administration & dosage/adverse effects/*therapeutic use
MH  - Glioma/*drug therapy/surgery
MH  - Humans
MH  - Surveys and Questionnaires
EDAT- 2016/05/24 06:00
MHDA- 2016/07/22 06:00
CRDT- 2016/05/24 06:00
PHST- 2016/05/24 06:00 [entrez]
PHST- 2016/05/24 06:00 [pubmed]
PHST- 2016/07/22 06:00 [medline]
PST - ppublish
SO  - Gan To Kagaku Ryoho. 2016 May;43(5):603-7.