PMID- 27215516
OWN - NLM
STAT- MEDLINE
DCOM- 20161005
LR  - 20181202
IS  - 1671-0274 (Print)
IS  - 1671-0274 (Linking)
VI  - 19
IP  - 5
DP  - 2016 May
TI  - [Application of radiotherapy in perioperative comprehensive treatment for the 
      elderly with rectal cancer].
PG  - 511-3
AB  - Considered that most of the phase II or III clinical trials contain less elderly 
      patients or only contain those who had good health status, these results might 
      not be applied in those elderly patients with some complex status. The patients 
      of 70 years old or more usually have complications or worse organ function, thus 
      the standard treatment for them becomes a gray zone. In rectal cancer patients, 
      the rate of elderly patients receiving standard chemoradiotherapy (CRT) is 
      obviously lower than that of the younger ones. More and more retrospective 
      studies found that the prognosis of the elderly (>/=70) who received neo-adjuvant 
      or adjuvant CRT was better than that of those who received surgery or 
      radiotherapy only, and the outcome of the above-mentioned elderly was similar to 
      those of other phase III trial or younger patients with good tolerance. In 
      addition, some studies revealed patients with good status, less or slight 
      complications had a better prognosis. The advance of radiation therapy, such as 
      Image-guided Radiation Therapy (IGRT), Intensity-modulated Radiation Therapy 
      (IMRT), Stereotactic Body Radiation Therapy (SBRT), brachytherapy and particle 
      therapy, will benefit the elderly cancer patients. We think that treatments 
      recommended to the elderly will become more personalized.
FAU - Cai, Xin
AU  - Cai X
AD  - Department of Radiotherapy, Shanghai Proton and Heavy Ion Center, Shanghai 
      201315, China.
FAU - Zhang, Zhen
AU  - Zhang Z
AD  - Department of Radiotherapy, Shangahi Cancer Center, Fudan University; Department 
      of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China. 
      zhenzhang6@gmail.com.
LA  - chi
PT  - Journal Article
PL  - China
TA  - Zhonghua Wei Chang Wai Ke Za Zhi
JT  - Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
JID - 101177990
SB  - IM
MH  - Aged
MH  - Brachytherapy
MH  - Chemoradiotherapy
MH  - Clinical Trials as Topic
MH  - Humans
MH  - Prognosis
MH  - Radiotherapy, Image-Guided
MH  - Radiotherapy, Intensity-Modulated
MH  - Rectal Neoplasms/*radiotherapy
MH  - Retrospective Studies
EDAT- 2016/05/25 06:00
MHDA- 2016/10/07 06:00
CRDT- 2016/05/25 06:00
PHST- 2016/05/25 06:00 [entrez]
PHST- 2016/05/25 06:00 [pubmed]
PHST- 2016/10/07 06:00 [medline]
AID - 100001882012 [pii]
PST - ppublish
SO  - Zhonghua Wei Chang Wai Ke Za Zhi. 2016 May;19(5):511-3.