PMID- 27240454
OWN - NLM
STAT- MEDLINE
DCOM- 20170207
LR  - 20200330
IS  - 1432-1084 (Electronic)
IS  - 0938-7994 (Linking)
VI  - 27
IP  - 2
DP  - 2017 Feb
TI  - Using 80 kVp on a 320-row scanner for hepatic multiphasic CT reduces the contrast 
      dose by 50 % in patients at risk for contrast-induced nephropathy.
PG  - 812-820
LID - 10.1007/s00330-016-4435-y [doi]
AB  - OBJECTIVES: We evaluated the effects of a low contrast material (CM) dose 
      protocol using 80-kVp on the image quality of hepatic multiphasic CT scans 
      acquired on a 320-row CT scanner. METHODS: We scanned 30 patients with renal 
      insufficiency (eGFR < 45 mL/min/1.73 m(2)) using 80-kVp and a CM dose of 
      300mgI/kg. Another 30 patients without renal insufficiency 
      (eGFR > 60 mL/min/1.73 m(2)) were scanned with the conventional 120-kVp protocol 
      and the standard CM dose of 600mgI/kg. Quantitative image quality parameters, 
      i.e. CT attenuation, image noise, and the contrast-to-noise ratio (CNR) were 
      compared and the visual image quality was scored on a four-point scale. The 
      volume CT dose index (CTDI(vol)) and the size-specific dose estimate (SSDE) 
      recorded with the 80- and the 120-kVp protocols were also compared. RESULTS: 
      Image noise and contrast enhancement were equivalent for the two protocols. There 
      was no significant difference in the CNR of all anatomic sites and in the visual 
      scores for overall image quality. The CTDI(vol) and SSDE were approximately 
      25-30 % lower under the 80-kVp protocol. CONCLUSION: Hepatic multiphase CT using 
      80-kVp on a 320-row CT scanner allowed for a decrease in the CM dose and a 
      reduction in the radiation dose without image quality degradation in patients 
      with renal insufficiency. KEY POINTS: * The 80-kVp CT protocol enabled reduction 
      of contrast dose by 50 % * The 80-kVp CT protocol reduced the radiation dose by 
      25-33 % * There was no degradation in the image quality of the 80-kVp protocol.
FAU - Taguchi, Narumi
AU  - Taguchi N
AD  - Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto 
      University, 1-1-1 Honjyo, Chuou-ku, Kumamoto, 860-8556, Japan.
FAU - Oda, Seitaro
AU  - Oda S
AD  - Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto 
      University, 1-1-1 Honjyo, Chuou-ku, Kumamoto, 860-8556, Japan. 
      seisei0430@nifty.com.
FAU - Utsunomiya, Daisuke
AU  - Utsunomiya D
AD  - Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto 
      University, 1-1-1 Honjyo, Chuou-ku, Kumamoto, 860-8556, Japan.
FAU - Funama, Yoshinori
AU  - Funama Y
AD  - Department of Medical Physics, Faculty of Life Sciences, Kumamoto University, 
      1-1-1 Honjyo, Chuo-ku, Kumamoto, 860-8556, Japan.
FAU - Nakaura, Takeshi
AU  - Nakaura T
AD  - Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto 
      University, 1-1-1 Honjyo, Chuou-ku, Kumamoto, 860-8556, Japan.
FAU - Imuta, Masanori
AU  - Imuta M
AD  - Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto 
      University, 1-1-1 Honjyo, Chuou-ku, Kumamoto, 860-8556, Japan.
FAU - Yamamura, Sadahiro
AU  - Yamamura S
AD  - Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto 
      University, 1-1-1 Honjyo, Chuou-ku, Kumamoto, 860-8556, Japan.
FAU - Yuki, Hideaki
AU  - Yuki H
AD  - Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto 
      University, 1-1-1 Honjyo, Chuou-ku, Kumamoto, 860-8556, Japan.
FAU - Kidoh, Masafumi
AU  - Kidoh M
AD  - Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto 
      University, 1-1-1 Honjyo, Chuou-ku, Kumamoto, 860-8556, Japan.
FAU - Hirata, Kenichiro
AU  - Hirata K
AD  - Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto 
      University, 1-1-1 Honjyo, Chuou-ku, Kumamoto, 860-8556, Japan.
FAU - Namimoto, Tomohiro
AU  - Namimoto T
AD  - Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto 
      University, 1-1-1 Honjyo, Chuou-ku, Kumamoto, 860-8556, Japan.
FAU - Hatemura, Masahiro
AU  - Hatemura M
AD  - Department of Central Radiology, Kumamoto University Hospital, 1-1-1 Honjyo, 
      Chuo-ku, Kumamoto, 860-8556, Japan.
FAU - Kai, Noriyuki
AU  - Kai N
AD  - Department of Central Radiology, Kumamoto University Hospital, 1-1-1 Honjyo, 
      Chuo-ku, Kumamoto, 860-8556, Japan.
FAU - Yamashita, Yasuyuki
AU  - Yamashita Y
AD  - Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto 
      University, 1-1-1 Honjyo, Chuou-ku, Kumamoto, 860-8556, Japan.
LA  - eng
PT  - Journal Article
DEP - 20160530
PL  - Germany
TA  - Eur Radiol
JT  - European radiology
JID - 9114774
RN  - 0 (Contrast Media)
SB  - IM
MH  - Acute Kidney Injury/chemically induced/*prevention & control
MH  - Aged
MH  - Aged, 80 and over
MH  - Case-Control Studies
MH  - Contrast Media/*administration & dosage/adverse effects
MH  - Female
MH  - Humans
MH  - Liver/*diagnostic imaging
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - *Radiation Dosage
MH  - Radiographic Image Enhancement
MH  - Radiographic Image Interpretation, Computer-Assisted/methods
MH  - *Renal Insufficiency
MH  - Tomography, X-Ray Computed/*methods
OTO - NOTNLM
OT  - 320-row CT
OT  - 80 kVp
OT  - Contrast-induced nephropathy
OT  - Hepatic multiphasic CT
OT  - Image quality
EDAT- 2016/06/01 06:00
MHDA- 2017/02/09 06:00
CRDT- 2016/06/01 06:00
PHST- 2016/02/09 00:00 [received]
PHST- 2016/05/20 00:00 [accepted]
PHST- 2016/05/17 00:00 [revised]
PHST- 2016/06/01 06:00 [pubmed]
PHST- 2017/02/09 06:00 [medline]
PHST- 2016/06/01 06:00 [entrez]
AID - 10.1007/s00330-016-4435-y [pii]
AID - 10.1007/s00330-016-4435-y [doi]
PST - ppublish
SO  - Eur Radiol. 2017 Feb;27(2):812-820. doi: 10.1007/s00330-016-4435-y. Epub 2016 May 
      30.