PMID- 27241587
OWN - NLM
STAT- MEDLINE
DCOM- 20160922
LR  - 20170112
IS  - 0392-856X (Print)
IS  - 0392-856X (Linking)
VI  - 34
IP  - 3 Suppl 97
DP  - 2016 May-Jun
TI  - Assessment of work limitations and disability in systemic vasculitis.
PG  - S111-4
AB  - OBJECTIVES: Despite advances in the management of systemic vasculitis (SV), 
      direct consequences of the disease, leading to impairments in physical and mental 
      function can cause disability. The objective of this study was to assess work 
      limitations in SV. METHODS: SV patients were recruited from a tertiary care 
      clinic. Work disabled (WD) was defined as not working, early retirement, or 
      reduced hours at work. Participants who were working at the time of enrolment 
      completed the Work Limitations Questionnaire (WLQ). Other work-related measures 
      were self-reported by questionnaire. Disease outcome measures (Vasculitis Damage 
      Index (VDI), Health Assessment Questionnaire-Disability Index (HAQ) and pain 
      visual analogue score (VAS)) were obtained at time of WLQ. RESULTS: 103 
      participants were enrolled with mean age 58 (SD17), 60% females, 48% with 
      anti-neutrophilic cytoplasmic antibody-associated vasculitis (AAV), 26% with 
      large vessel vasculitis (LVV) and 26% with other types of SV. 22 (21%) were WD 
      secondary to SV, 29 (28%) were working and 52 (51%) subjects were not working for 
      reasons other than SV. SV-related WD subjects were more likely to have a lower 
      level of education (p=0.003) than non-WD subjects. The VDI was higher in 
      SV-related WD vs. non-WD subjects: 1.9 (SD 2.7) vs. 2.9 (SD 1.4); p=0.015. 38 
      subjects were working in some capacity and completed the WLQ; their productivity 
      loss was 8.2% and this was highly correlated with HAQ and pain VAS (rho=0.585 and 
      rho=0.458, respectively). CONCLUSIONS: SV-related work disability occurred in 21% 
      and was associated with lower levels of education, higher disease severity and 
      worse functional outcomes.
FAU - Barra, Lillian J
AU  - Barra LJ
AD  - Department of Medicine, Division of Rheumatology, Schulich School of Medicine & 
      Dentistry, Western University, London, ON, Canada. lbarra2@uwo.ca.
FAU - Bateman, Emma A
AU  - Bateman EA
AD  - Department of Medicine, Division of Rheumatology, Schulich School of Medicine & 
      Dentistry, Western University, London, ON, Canada.
FAU - Rohekar, Sherry
AU  - Rohekar S
AD  - Department of Medicine, Division of Rheumatology, Schulich School of Medicine & 
      Dentistry, Western University, London, ON, Canada.
FAU - Pagnoux, Christian
AU  - Pagnoux C
AD  - Department of Medicine, Mount Sinai, Toronto, ON, Canada.
FAU - Moradizadeh, Manoosh
AU  - Moradizadeh M
AD  - Department of Medicine, Division of Rheumatology, Schulich School of Medicine & 
      Dentistry, Western University, London, ON, Canada.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20160524
PL  - Italy
TA  - Clin Exp Rheumatol
JT  - Clinical and experimental rheumatology
JID - 8308521
SB  - IM
MH  - Adult
MH  - *Disability Evaluation
MH  - Efficiency
MH  - *Employment
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Severity of Illness Index
MH  - Surveys and Questionnaires
MH  - Systemic Vasculitis/*physiopathology
MH  - *Work Capacity Evaluation
EDAT- 2016/06/01 06:00
MHDA- 2016/09/23 06:00
CRDT- 2016/06/01 06:00
PHST- 2016/01/12 00:00 [received]
PHST- 2016/05/10 00:00 [accepted]
PHST- 2016/06/01 06:00 [entrez]
PHST- 2016/06/01 06:00 [pubmed]
PHST- 2016/09/23 06:00 [medline]
AID - 10303 [pii]
PST - ppublish
SO  - Clin Exp Rheumatol. 2016 May-Jun;34(3 Suppl 97):S111-4. Epub 2016 May 24.