PMID- 27259099 OWN - NLM STAT- MEDLINE DCOM- 20170413 LR - 20170413 IS - 1439-3964 (Electronic) IS - 0172-4622 (Linking) VI - 37 IP - 9 DP - 2016 Aug TI - Low-Volume High-Intensity Interval Training as a Therapy for Type 2 Diabetes. PG - 723-9 LID - 10.1055/s-0042-104935 [doi] AB - Our purpose was to investigate the effects of low-volume, high-intensity interval training (HIT) on cardiometabolic risk and exercise capacity in women with type 2 diabetes mellitus (T2DM). Sedentary overweight/obese T2DM women (age=44.5+/-1.8 years; BMI=30.5+/-0.6 kg/m(2)) were randomly assigned to a tri-weekly running-based HIT program (n=13) or non-exercise control follow-up (CON; n=10). Glycemic control, lipid and blood pressure levels, endurance performance, and anthropometry were measured before and after the follow-up (16 weeks) in both groups. Medication intake was also assessed throughout the follow-up. Improvements (P<0.05) on fasting glucose (14.3+/-1.4%), HbA1c (12.8+/-1.1%), systolic blood pressure (3.7+/-0.5 mmHg), HDL-cholesterol (21.1+/-2.8%), triglycerides (17.7+/-2.8%), endurance performance (9.8+/-1.0%), body weight (2.2+/-0.3%), BMI (2.1+/-0.3%), waist circumference (4.0+/-0.5%) and subcutaneous fat (18.6+/-1.4%) were found after HIT intervention. Patients of HIT group also showed reductions in daily dosage of antihyperglycemic and antihypertensive medication during follow-up. No changes were found in any variable of CON group. The HIT-induced improvements occurred with a weekly time commitment 56-25% lower than the minimal recommended in current guidelines. These findings suggest that low-volume HIT may be a time-efficient intervention to treat T2DM women. CI - (c) Georg Thieme Verlag KG Stuttgart . New York. FAU - Alvarez, C AU - Alvarez C AD - Cardiovascular Health Program, Centro de Salud Familiar, Los Lagos, Chile. FAU - Ramirez-Campillo, R AU - Ramirez-Campillo R AD - Department of Physical Activity Sciences, Universidad de Los Lagos, Osorno, Chile. FAU - Martinez-Salazar, C AU - Martinez-Salazar C AD - Department of Physical Education and Recreation, Faculty of Education, Social Sciences and Humanities, Universidad de la Frontera, Temuco, Chile. FAU - Mancilla, R AU - Mancilla R AD - Department of Human Movement Science, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands. FAU - Flores-Opazo, M AU - Flores-Opazo M AD - Department of Physiology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Victoria, Australia. FAU - Cano-Montoya, J AU - Cano-Montoya J AD - Rehabilitation, Public Hospital of Los Lagos, Los Lagos, Chile. FAU - Ciolac, E G AU - Ciolac EG AD - Exercise and Chronic Disease Research Laboratory, Physical Education Department, School of Sciences, Sao Paulo State Univiersity - UNESP. LA - eng PT - Journal Article PT - Randomized Controlled Trial DEP - 20160603 PL - Germany TA - Int J Sports Med JT - International journal of sports medicine JID - 8008349 RN - 0 (Antihypertensive Agents) RN - 0 (Blood Glucose) RN - 0 (Hypoglycemic Agents) RN - 0 (Lipids) SB - IM MH - Adult MH - Antihypertensive Agents/therapeutic use MH - Blood Glucose/analysis MH - Blood Pressure MH - Body Weight MH - Diabetes Mellitus, Type 2/*therapy MH - *Exercise Therapy MH - Female MH - *High-Intensity Interval Training MH - Humans MH - Hypoglycemic Agents/therapeutic use MH - Lipids/blood MH - Middle Aged MH - Obesity/blood MH - Overweight/blood MH - Physical Endurance MH - Waist Circumference EDAT- 2016/06/04 06:00 MHDA- 2017/04/14 06:00 CRDT- 2016/06/04 06:00 PHST- 2016/06/04 06:00 [entrez] PHST- 2016/06/04 06:00 [pubmed] PHST- 2017/04/14 06:00 [medline] AID - 10.1055/s-0042-104935 [doi] PST - ppublish SO - Int J Sports Med. 2016 Aug;37(9):723-9. doi: 10.1055/s-0042-104935. Epub 2016 Jun 3.