PMID- 27260526
OWN - NLM
STAT- MEDLINE
DCOM- 20171207
LR  - 20240213
IS  - 1873-4626 (Electronic)
IS  - 1091-255X (Linking)
VI  - 20
IP  - 8
DP  - 2016 Aug
TI  - Choledochal Cyst Disease in a Western Center: A 30-Year Experience.
PG  - 1453-63
LID - 10.1007/s11605-016-3181-4 [doi]
AB  - BACKGROUND: The aim of this study was to report a Western experience in the 
      diagnosis and management of choledochal cyst disease. RESULTS: Sixty-seven 
      patients were identified including 15 children and 52 adults; 76.1 % were 
      females. The median age at diagnosis was 3 [inter-quartile range 
      (IQR) = 6.0-0.7] years for children, and 46 [IQR = 55.6-34.3] years for adults. 
      Forty-eight patients (72 %) were symptomatic. Types of choledochal cyst included: 
      I (n = 49, 73.1 %), II (n = 1, 1.5 %), IV (n = 9, 13.4 %), and V (n = 8, 12 %). 
      The median diameter of the type I choledochal cyst was 35 [IQR = 47-25] mm. All 
      48 patients underwent excision of cyst with Roux-en-Y hepaticojejunostomy, and 
      eight underwent resection with hepaticoduodenostomy. Six patients underwent liver 
      resection, and five patients underwent orthotopic liver transplantation. 
      Malignancy was concomitant in five adult patients, being identified on 
      preoperative imaging in three cases; and atypia was seen in three additional 
      patients. Early morbidity included Clavien-Dindo classification grades III 
      (n = 7) and II (n = 5), while long-term complications consisted of Clavien-Dindo 
      grades V (n = 5), IV (n = 2), III (n = 18), and II (n = 1). CONCLUSIONS: 
      Presentation and management of choledochal cyst is varied. Malignant 
      transformation is often detected incidentally, and so should be the driving 
      source for resection when a choledochal cyst is diagnosed.
FAU - Moslim, Maitham A
AU  - Moslim MA
AD  - Department of HPB Surgery, Digestive Disease Institute, Cleveland Clinic 
      Foundation, 9500 Euclid Avenue, Cleveland, OH, 44195, USA. moslimm@ccf.org.
FAU - Takahashi, Hideo
AU  - Takahashi H
AD  - Department of HPB Surgery, Digestive Disease Institute, Cleveland Clinic 
      Foundation, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
FAU - Seifarth, Federico G
AU  - Seifarth FG
AD  - Department of Pediatric Surgery, Cleveland Clinic Children's Hospital, Cleveland 
      Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
FAU - Walsh, R Matthew
AU  - Walsh RM
AD  - Department of HPB Surgery, Digestive Disease Institute, Cleveland Clinic 
      Foundation, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
FAU - Morris-Stiff, Gareth
AU  - Morris-Stiff G
AD  - Department of HPB Surgery, Digestive Disease Institute, Cleveland Clinic 
      Foundation, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
LA  - eng
PT  - Journal Article
DEP - 20160603
PL  - Netherlands
TA  - J Gastrointest Surg
JT  - Journal of gastrointestinal surgery : official journal of the Society for Surgery 
      of the Alimentary Tract
JID - 9706084
SB  - IM
MH  - Adult
MH  - Anastomosis, Roux-en-Y
MH  - Anastomosis, Surgical
MH  - Child
MH  - Child, Preschool
MH  - Choledochal Cyst/complications/*diagnosis/*surgery
MH  - Duodenostomy
MH  - Female
MH  - Humans
MH  - Infant
MH  - Liver/surgery
MH  - Liver Neoplasms/complications
MH  - Liver Transplantation
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
OTO - NOTNLM
OT  - Caroli's disease
OT  - Choledochal cyst
OT  - Hepaticoduodenostomy
OT  - Hepaticojejunostomy
OT  - Liver resection
EDAT- 2016/06/05 06:00
MHDA- 2017/12/08 06:00
CRDT- 2016/06/05 06:00
PHST- 2016/04/18 00:00 [received]
PHST- 2016/05/27 00:00 [accepted]
PHST- 2016/06/05 06:00 [entrez]
PHST- 2016/06/05 06:00 [pubmed]
PHST- 2017/12/08 06:00 [medline]
AID - S1091-255X(23)06671-4 [pii]
AID - 10.1007/s11605-016-3181-4 [doi]
PST - ppublish
SO  - J Gastrointest Surg. 2016 Aug;20(8):1453-63. doi: 10.1007/s11605-016-3181-4. Epub 
      2016 Jun 3.