PMID- 27262371
OWN - NLM
STAT- MEDLINE
DCOM- 20161219
LR  - 20181202
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1454
DP  - 2016 Jul 8
TI  - Determination of methacrylic acid in food simulants by pyrolytic butylation-gas 
      chromatography.
PG  - 101-6
LID - S0021-9673(16)30675-6 [pii]
LID - 10.1016/j.chroma.2016.05.068 [doi]
AB  - An on-line pyrolytic butylation approach was proposed to determine methacrylic 
      acid (MA) in food simulants by gas chromatography (GC) without an expensive 
      pyrolyzer. MA in food simulants was converted into butyl methacrylate in the 
      presence of tetrabutylammonium hydroxide (TBAH) without any pretreatment at 330 degrees C 
      in the injection-port, contributing to high GC signal response. The derivatizing 
      conditions for the proposed method were optimized, namely the injection-port 
      temperature, type and amount of the organic alkaline used for derivatization. A 
      series of standard solutions of MA in the range of 1.0-50mg/kg were analyzed with 
      correlation coefficient r>/=0.9975. The limits of detection (LODs) were less than 
      0.15mg/kg for MA in four matrix simulants (distilled water, 3%w/v acetic acid, 
      10%v/v ethanol, and isooctane). Relative standard deviations (RSDs) for retention 
      time, peak height and peak area were all less than 3.88%. The technique was 
      successfully applied to the analysis of MA migrating from plastic cup samples, 
      with recoveries of added MA in the range of 96.5-123.0%. Direct injection of the 
      simulants into the GC system after migration tests, without any pretreatment 
      step, makes the developed method of great value for rapid screening analysis of 
      samples in bulks.
CI  - Copyright (c) 2016 Elsevier B.V. All rights reserved.
FAU - Huang, Zhongping
AU  - Huang Z
AD  - College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, 
      Zhejiang, 310014, PR China.
FAU - Qiu, Ruofeng
AU  - Qiu R
AD  - College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, 
      Zhejiang, 310014, PR China.
FAU - Liu, Tingfei
AU  - Liu T
AD  - College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, 
      Zhejiang, 310014, PR China; Taizhou Entry-Exit Inspection and Quarantine Bureau, 
      Taizhou, Zhejiang, 318000, PR China.
FAU - Huang, Yilei
AU  - Huang Y
AD  - College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, 
      Zhejiang, 310014, PR China.
FAU - Zhu, Zuoyi
AU  - Zhu Z
AD  - Institute of Quality and Standard for Agricultural Products, Zhejiang Academy of 
      Agricultural Sciences, Hangzhou, 310021, PR China.
FAU - Wang, Lili
AU  - Wang L
AD  - College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, 
      Zhejiang, 310014, PR China. Electronic address: lili_wang@zjut.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20160521
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Methacrylates)
RN  - 1CS02G8656 (methacrylic acid)
RN  - R5QX287XXU (butyl methacrylate)
SB  - IM
MH  - Chromatography, Gas/*methods
MH  - Food Analysis/*methods
MH  - Hot Temperature
MH  - Limit of Detection
MH  - Methacrylates/*analysis
MH  - Reproducibility of Results
OTO - NOTNLM
OT  - Food packaging
OT  - Gas chromatography
OT  - Methacrylic acid
OT  - Migration
OT  - Pyrolytic butylation
EDAT- 2016/06/06 06:00
MHDA- 2016/12/20 06:00
CRDT- 2016/06/06 06:00
PHST- 2016/01/11 00:00 [received]
PHST- 2016/05/19 00:00 [revised]
PHST- 2016/05/20 00:00 [accepted]
PHST- 2016/06/06 06:00 [entrez]
PHST- 2016/06/06 06:00 [pubmed]
PHST- 2016/12/20 06:00 [medline]
AID - S0021-9673(16)30675-6 [pii]
AID - 10.1016/j.chroma.2016.05.068 [doi]
PST - ppublish
SO  - J Chromatogr A. 2016 Jul 8;1454:101-6. doi: 10.1016/j.chroma.2016.05.068. Epub 
      2016 May 21.