PMID- 27263513
OWN - NLM
STAT- MEDLINE
DCOM- 20170209
LR  - 20170209
IS  - 1096-9098 (Electronic)
IS  - 0022-4790 (Linking)
VI  - 114
IP  - 4
DP  - 2016 Sep
TI  - Robot-assisted spleen preserving pancreatic surgery in MEN1 patients.
PG  - 456-61
LID - 10.1002/jso.24315 [doi]
AB  - BACKGROUND: Multiple Endocrine Neoplasia type 1 (MEN1) patients often undergo 
      multiple pancreatic operations at a young age. OBJECTIVE: To describe 
      robot-assisted and laparoscopic spleen-preserving pancreatic surgery in MEN1 
      patients, and to compare both techniques. METHODS: Robot-assisted 
      pancreatectomies of the DutchMEN1 study group and the Universite de Lorraine, 
      Nancy, France were compared to a historical cohort of laparoscopic treated MEN1 
      patients. Perioperative outcomes were compared. RESULTS: A total of 21 MEN1 
      patients underwent minimally invasive pancreatic surgery for pancreatic 
      neuroendocrine tumors, seven patients were subjected to robot-assisted surgery, 
      and 14 patients underwent laparoscopic surgery. Demographics and clinical 
      characteristics did not differ between the cohorts and no significant differences 
      in operative outcomes were found. A high number of ISGPS grade B/C pancreatic 
      fistulas were observed in both cohorts (38%), and no conversions were seen in the 
      robot-assisted cohort (respectively 0% vs. 43%, P = 0.06). In one laparoscopic 
      and one robot-assisted case the primary tumor was not resected. CONCLUSIONS: 
      Minimally invasive spleen-preserving surgery in MEN1 patients is safe and 
      feasible. Patients who underwent robot-assisted surgery did not require 
      conversion to open surgery. J. Surg. Oncol. 2016;114:456-461. (c) 2016 Wiley 
      Periodicals, Inc.
CI  - (c) 2016 Wiley Periodicals, Inc.
FAU - Nell, Sjoerd
AU  - Nell S
AD  - Department of Endocrine Surgical Oncology and Endocrine Oncology, University 
      Medical Center Utrecht, Utrecht, The Netherlands.
FAU - Brunaud, Laurent
AU  - Brunaud L
AD  - Department of Digestive, Hepatobiliary and Endocrine Surgery, Universite de 
      Lorraine, Hopital Brabois Adultes, CHU Nancy, Nancy, France.
FAU - Ayav, Ahmet
AU  - Ayav A
AD  - Department of Digestive, Hepatobiliary and Endocrine Surgery, Universite de 
      Lorraine, Hopital Brabois Adultes, CHU Nancy, Nancy, France.
FAU - Bonsing, Bert A
AU  - Bonsing BA
AD  - Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.
FAU - Groot Koerkamp, Bas
AU  - Groot Koerkamp B
AD  - Department of Surgery, Erasmus Medical Center, Rotterdam, The Netherlands.
FAU - Nieveen van Dijkum, Els J
AU  - Nieveen van Dijkum EJ
AD  - Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands.
FAU - Kazemier, Geert
AU  - Kazemier G
AD  - Department of Surgery, VU University Medical Center, Amsterdam, The Netherlands.
FAU - de Kleine, Ruben H J
AU  - de Kleine RH
AD  - Department of Hepatobiliary Surgery and Liver Transplantation, University of 
      Groningen, University Medical Center Groningen, Groningen, The Netherlands.
FAU - Hagendoorn, Jeroen
AU  - Hagendoorn J
AD  - Department of Surgical Oncology and Hepato-Pancreato-Biliary Surgery, University 
      Medical Center Utrecht, Utrecht, The Netherlands.
FAU - Molenaar, I Quintus
AU  - Molenaar IQ
AD  - Department of Surgical Oncology and Hepato-Pancreato-Biliary Surgery, University 
      Medical Center Utrecht, Utrecht, The Netherlands.
FAU - Valk, Gerlof D
AU  - Valk GD
AD  - Department of Endocrine Oncology, University Medical Center Utrecht, Utrecht, The 
      Netherlands.
CN  - DMSG
FAU - Borel Rinkes, Inne H M
AU  - Borel Rinkes IH
AD  - Department of Surgical Oncology and Endocrine Surgical Oncology, University 
      Medical Center Utrecht, Utrecht, The Netherlands.
FAU - Vriens, Menno R
AU  - Vriens MR
AD  - Department of Endocrine Surgical Oncology, University Medical Center Utrecht, 
      Utrecht, The Netherlands.
LA  - eng
PT  - Journal Article
DEP - 20160606
PL  - United States
TA  - J Surg Oncol
JT  - Journal of surgical oncology
JID - 0222643
SB  - IM
MH  - Adult
MH  - Female
MH  - Humans
MH  - Laparoscopy
MH  - Male
MH  - Minimally Invasive Surgical Procedures
MH  - Multiple Endocrine Neoplasia Type 1/*surgery
MH  - Pancreatectomy/*methods
MH  - Pancreatic Neoplasms/*surgery
MH  - Robotic Surgical Procedures/*methods
MH  - Spleen/*surgery
OTO - NOTNLM
OT  - laparoscopic pancreatic surgery
OT  - multiple endocrine neoplasia type 1
OT  - neuroendocrine tumors
OT  - pancreas
OT  - robot-assisted pancreatic surgery
EDAT- 2016/06/07 06:00
MHDA- 2017/02/10 06:00
CRDT- 2016/06/07 06:00
PHST- 2015/09/02 00:00 [received]
PHST- 2016/05/21 00:00 [accepted]
PHST- 2016/06/07 06:00 [entrez]
PHST- 2016/06/07 06:00 [pubmed]
PHST- 2017/02/10 06:00 [medline]
AID - 10.1002/jso.24315 [doi]
PST - ppublish
SO  - J Surg Oncol. 2016 Sep;114(4):456-61. doi: 10.1002/jso.24315. Epub 2016 Jun 6.