PMID- 27263638 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20160607 LR - 20160606 IS - 1300-7777 (Print) IS - 1300-7777 (Linking) VI - 17 IP - 4 DP - 2000 Dec 5 TI - Impact of Fluorescence in Situ Hybridization in the Detection of Cryptic Fusion Transcript PML/RARA and A Complex t(5;15;17) in a Case of Acute Promyelocytic Leukemia. PG - 207-12 AB - Genetic aspects of a 28 year-old female patient with typical morphological and clinical features of acute promyelocytic leukemia is presented. Pml/rara fusion transcript and a complex translocation involving chromosomes 5, 15 and 17 were detected by fluorescence in situ hybridization (FISH) technique which was applied as in adjunct to conventional cytogenetics. The patient deceased soon in spite of the immediate ATRA and cytostatic therapy. FAU - Ogur, G AU - Ogur G FAU - Fen, T AU - Fen T FAU - Sucak, G AU - Sucak G FAU - Heimann, P AU - Heimann P FAU - Cankus, G AU - Cankus G FAU - Haznedar, R AU - Haznedar R LA - eng PT - Journal Article PL - Turkey TA - Turk J Haematol JT - Turkish journal of haematology : official journal of Turkish Society of Haematology JID - 9606065 EDAT- 2000/12/05 00:00 MHDA- 2000/12/05 00:01 CRDT- 2016/06/07 06:00 PHST- 2016/06/07 06:00 [entrez] PHST- 2000/12/05 00:00 [pubmed] PHST- 2000/12/05 00:01 [medline] PST - ppublish SO - Turk J Haematol. 2000 Dec 5;17(4):207-12.