PMID- 27264875
OWN - NLM
STAT- MEDLINE
DCOM- 20170306
LR  - 20170723
IS  - 1879-1476 (Electronic)
IS  - 0385-8146 (Linking)
VI  - 44
IP  - 1
DP  - 2017 Feb
TI  - HIV-associated cystic lesions of the parotid gland.
PG  - 126-130
LID - S0385-8146(16)30160-2 [pii]
LID - 10.1016/j.anl.2016.05.011 [doi]
AB  - We present two cases of an HIV-associated parotid gland cyst. One case was a 
      36-year-old HIV infected woman. She was diagnosed with HIV infection and 
      presented with slowly enlarged parotid gland cysts together with elevation of HIV 
      viral RNA copies/mL in her serum. She was performed parotid gland biopsy under 
      the general anesthesia. The histopathologic analysis revealed negative HIV 
      p24-antigen in her parotid gland tissue. The other case was a 43-year-old man 
      found his parotid gland swelling shortly after highly active antiretroviral 
      therapy (HAART). He was diagnosed with HIV infection 2 years previously. He had 
      started HAART several days before. He showed exceeding elevation of IgE in his 
      serum. We treated him with medication using anti-histamic drugs for his cyst. A 
      computed tomography scan revealed a complete response of his parotid gland cyst 4 
      weeks after the medication. His serum IgE level was decreased to half of the 
      level before the medication. These findings suggested that the parotid gland 
      swelling associated with HIV was due to various factors including immune 
      reconstitution inflammatory syndrome (IRIS). In case such a parotid gland 
      swelling, we could avoid invasive treatments.
CI  - Copyright (c) 2016 Elsevier Ireland Ltd. All rights reserved.
FAU - Ogasawara, Noriko
AU  - Ogasawara N
AD  - Department of Otorhinolaryngology, Sapporo Medical University School of Medicine, 
      Sapporo, Japan; Department of Otorhinolaryngology, Obihiro Kousei Hospital, 
      Japan. Electronic address: ogasawara.n@sapmed.ac.jp.
FAU - Takano, Ken-Ichi
AU  - Takano KI
AD  - Department of Otorhinolaryngology, Sapporo Medical University School of Medicine, 
      Sapporo, Japan.
FAU - Kobayashi, Hajime
AU  - Kobayashi H
AD  - Department of Internal Medicine, Obihiro Kousei Hospital, Japan.
FAU - Kikuchi, Keisuke
AU  - Kikuchi K
AD  - Department of Pathology, Obihiro Kousei Hospital, Japan.
FAU - Matsumiya, Hiroshi
AU  - Matsumiya H
AD  - Department of Otorhinolaryngology, Sapporo Medical University School of Medicine, 
      Sapporo, Japan.
FAU - Yoshioka, Iwao
AU  - Yoshioka I
AD  - Department of Otorhinolaryngology, Obihiro Kousei Hospital, Japan.
FAU - Himi, Tetsuo
AU  - Himi T
AD  - Department of Otorhinolaryngology, Sapporo Medical University School of Medicine, 
      Sapporo, Japan.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20160603
PL  - Netherlands
TA  - Auris Nasus Larynx
JT  - Auris, nasus, larynx
JID - 7708170
RN  - 0 (HIV Core Protein p24)
RN  - 0 (Histamine Antagonists)
RN  - 0 (RNA, Viral)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adult
MH  - Antiretroviral Therapy, Highly Active
MH  - Cysts/complications/diagnostic imaging/drug therapy/*immunology
MH  - Female
MH  - HIV Core Protein p24/metabolism
MH  - HIV Infections/complications/drug therapy/*immunology/metabolism
MH  - Histamine Antagonists/therapeutic use
MH  - Humans
MH  - Immune Reconstitution Inflammatory Syndrome/*immunology
MH  - Immunoglobulin E/*immunology
MH  - Male
MH  - Parotid Diseases/complications/diagnostic imaging/drug therapy/*immunology
MH  - RNA, Viral/metabolism
MH  - Tomography, X-Ray Computed
OTO - NOTNLM
OT  - HIV-associated
OT  - Hyper-IgE syndrome
OT  - Immune reconstitution inflammatory syndrome
OT  - Parotid gland cyst
EDAT- 2016/06/07 06:00
MHDA- 2017/03/07 06:00
CRDT- 2016/06/07 06:00
PHST- 2015/12/09 00:00 [received]
PHST- 2016/04/26 00:00 [revised]
PHST- 2016/05/13 00:00 [accepted]
PHST- 2016/06/07 06:00 [pubmed]
PHST- 2017/03/07 06:00 [medline]
PHST- 2016/06/07 06:00 [entrez]
AID - S0385-8146(16)30160-2 [pii]
AID - 10.1016/j.anl.2016.05.011 [doi]
PST - ppublish
SO  - Auris Nasus Larynx. 2017 Feb;44(1):126-130. doi: 10.1016/j.anl.2016.05.011. Epub 
      2016 Jun 3.