PMID- 27268499 OWN - NLM STAT- MEDLINE DCOM- 20170410 LR - 20220321 IS - 1473-2300 (Electronic) IS - 0300-0605 (Print) IS - 0300-0605 (Linking) VI - 44 IP - 4 DP - 2016 Aug TI - The diagnostic validity of clinical airway assessments for predicting difficult laryngoscopy using a grey zone approach. PG - 893-904 LID - 10.1177/0300060516642647 [doi] AB - OBJECTIVES: The diagnostic validity of clinical airway assessment tests for predicting difficult laryngoscopy in patients requiring endotracheal intubation were evaluated using receiver operating characteristic (ROC) curve analysis and a grey zone approach. METHODS: In this prospective observational study, patients were evaluated during a pre-anaesthetic visit. Predictive airway assessment tests (i.e. Modified Mallampati [MMT] classification; upper lip bite test [ULBT]; mouth opening; sternomental distance; thyromental distance [TMD]; neck circumference; neck mobility; height to thyromental distance [HT/TMD]; neck circumference-to-thyromental distance [NC/TMD]) were performed on each patient and LEMON, Naguib, and MACOCHA scores were also calculated. In addition, laryngeal images were acquired and assessed for percentage of glottic opening (POGO) scores. A POGO score of zero was categorized as difficult laryngoscopy. RESULTS: The incidence of difficult laryngoscopy was 14.4% (35/243). Although seven predictive airway assessments (i.e. MMT classification, ULBT, mouth opening, HT/TMD, NC/TMD, and the LEMON and Naguib models) predicted difficult laryngoscopy by ROC analyses, a grey zone approach showed that the parameters were inconclusive in approximately 70% of patients. From all the tests, the HT/TMD ratio showed the highest sensitivity (80.0%) and ULBT had the highest specificity (95.2%). CONCLUSION: Using the grey zone approach, all predictive airway assessment tests showed large inconclusive zones which may explain previous inconsistent results in the prediction of difficult laryngoscopy. Our results suggest that the usefulness of clinical airway evaluation tests for predicting difficult laryngoscopy remains controversial. CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov (NCT01719848). CI - (c) The Author(s) 2016. FAU - Min, Jeong Jin AU - Min JJ AD - Department of Anaesthesiology and Pain Medicine, Samsung Medical Centre, Sungkyunkwan University School of Medicine, Seoul, Korea. FAU - Kim, Gahyun AU - Kim G AD - Department of Anaesthesiology and Pain Medicine, Samsung Medical Centre, Sungkyunkwan University School of Medicine, Seoul, Korea. FAU - Kim, Eunhee AU - Kim E AD - Department of Anaesthesiology and Pain Medicine, Samsung Medical Centre, Sungkyunkwan University School of Medicine, Seoul, Korea. FAU - Lee, Jong-Hwan AU - Lee JH AD - Department of Anaesthesiology and Pain Medicine, Samsung Medical Centre, Sungkyunkwan University School of Medicine, Seoul, Korea jonghwanlee75@gmail.com. LA - eng SI - ClinicalTrials.gov/NCT01719848 PT - Journal Article PT - Observational Study DEP - 20160606 PL - England TA - J Int Med Res JT - The Journal of international medical research JID - 0346411 SB - IM MH - Female MH - Humans MH - *Laryngoscopy MH - Lung/*physiopathology MH - Male MH - Middle Aged MH - ROC Curve MH - Reproducibility of Results PMC - PMC5536638 OTO - NOTNLM OT - Airway assessment OT - difficult laryngoscopy OT - grey zone EDAT- 2016/06/09 06:00 MHDA- 2017/04/11 06:00 PMCR- 2016/08/01 CRDT- 2016/06/09 06:00 PHST- 2015/09/06 00:00 [received] PHST- 2016/03/11 00:00 [accepted] PHST- 2016/06/09 06:00 [entrez] PHST- 2016/06/09 06:00 [pubmed] PHST- 2017/04/11 06:00 [medline] PHST- 2016/08/01 00:00 [pmc-release] AID - 0300060516642647 [pii] AID - 10.1177_0300060516642647 [pii] AID - 10.1177/0300060516642647 [doi] PST - ppublish SO - J Int Med Res. 2016 Aug;44(4):893-904. doi: 10.1177/0300060516642647. Epub 2016 Jun 6.