PMID- 27277978
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160610
LR  - 20181113
IS  - 1346-4523 (Print)
IS  - 1346-4523 (Linking)
VI  - 33
IP  - 4
DP  - 2006 Dec
TI  - Predicting prognosis based on the shape of the left ventricular cavity in dilated 
      cardiomyopathy: analysis using rate of improvement in the circle index.
PG  - 217-24
LID - 10.1007/s10396-006-0113-z [doi]
AB  - PURPOSE: To elucidate the relation between a quantitative measure of the shape of 
      the left ventricular cavity, cardiac function, and prognosis in patients with 
      dilated cardiomyopathy (DCM). METHODS: The hearts of 20 healthy individuals and 
      18 patients with DCM were evaluated. Participants were aged 48.5 +/- 5.0 years. On 
      the basis of end-systolic four-chamber view echocardiograms, the endocardium of 
      the left ventricle was traced and the resulting curve was segmented using 100 
      points. A line tangential to the curve was then drawn at each point, and the 
      angle between two adjacent tangential lines was calculated. The deviation of 
      these angles was designated as the circle index. The circle index and hemodynamic 
      findings in patients with DCM were compared, and the rate of improvement in the 
      circle index in these cases of DCM was determined. These patients were then 
      placed into one of two groups: group R (11 patients), those with improvement 
      rates of 10% or higher at time of discharge; and group NR (seven patients), those 
      with rates less than 10%. Diuretic (furosemide) use, New York Heart Association 
      (NYHA) classification, and readmission rate for the two groups were compared 2 
      years after discharge. RESULTS: The circle index was 2.7 +/- 0.9 in the DCM group 
      and 17.5 +/- 4.2 in the healthy group (P < 0.01). The circle index in the DCM group 
      was correlated with pulmonary capillary wedge pressure (r(2) = 0.42). Use of 
      furosemide was unchanged in group R 2 years after discharge, but had increased 
      for all patients in group NR. All cases in group R were classified as NYHA I 2 
      years after discharge. In group NR, in contrast, although all cases were 
      classified as NYHA I at discharge, five of seven cases had deteriorated to NYHA 
      III-IV 2 years later and were readmitted to hospital. CONCLUSION: There appears 
      to be a quantifiable correlation between the circularity of the left ventricular 
      cavity and the circle index. This suggests that rate of improvement after 
      treatment for heart failure could predict prognosis in patients with DCM.
FAU - Hirano, Yuichi
AU  - Hirano Y
AD  - Third Department of Internal Medicine, Showa University School of Medicine, 1-5-8 
      Hatanodai, Shinagawa, Tokyo, 142-8666, Japan. hiranoysc@yahoo.co.jp.
FAU - Kayano, Hiroyuki
AU  - Kayano H
AD  - Third Department of Internal Medicine, Showa University School of Medicine, 1-5-8 
      Hatanodai, Shinagawa, Tokyo, 142-8666, Japan.
FAU - Kawamata, Tomoaki
AU  - Kawamata T
AD  - Third Department of Internal Medicine, Showa University School of Medicine, 1-5-8 
      Hatanodai, Shinagawa, Tokyo, 142-8666, Japan.
FAU - Toshida, Tsutomu
AU  - Toshida T
AD  - Third Department of Internal Medicine, Showa University School of Medicine, 1-5-8 
      Hatanodai, Shinagawa, Tokyo, 142-8666, Japan.
FAU - Ueda, Hiroaki
AU  - Ueda H
AD  - Third Department of Internal Medicine, Showa University School of Medicine, 1-5-8 
      Hatanodai, Shinagawa, Tokyo, 142-8666, Japan.
FAU - Ando, Hiromi
AU  - Ando H
AD  - Third Department of Internal Medicine, Showa University School of Medicine, 1-5-8 
      Hatanodai, Shinagawa, Tokyo, 142-8666, Japan.
FAU - Ozawa, Masaki
AU  - Ozawa M
AD  - Third Department of Internal Medicine, Showa University School of Medicine, 1-5-8 
      Hatanodai, Shinagawa, Tokyo, 142-8666, Japan.
FAU - Katagiri, Takashi
AU  - Katagiri T
AD  - Third Department of Internal Medicine, Showa University School of Medicine, 1-5-8 
      Hatanodai, Shinagawa, Tokyo, 142-8666, Japan.
FAU - Abe, Keisuke
AU  - Abe K
AD  - Kameari Hospital, Tokyo, Japan.
LA  - eng
PT  - Journal Article
DEP - 20061222
PL  - Japan
TA  - J Med Ultrason (2001)
JT  - Journal of medical ultrasonics (2001)
JID - 101128385
OTO - NOTNLM
OT  - circle index
OT  - dilated cardiomyopathy
OT  - echocardiography
OT  - left ventricular cavity shape
OT  - prognosis
EDAT- 2006/12/01 00:00
MHDA- 2006/12/01 00:01
CRDT- 2016/06/10 06:00
PHST- 2006/02/10 00:00 [received]
PHST- 2006/05/09 00:00 [accepted]
PHST- 2016/06/10 06:00 [entrez]
PHST- 2006/12/01 00:00 [pubmed]
PHST- 2006/12/01 00:01 [medline]
AID - 10.1007/s10396-006-0113-z [pii]
AID - 10.1007/s10396-006-0113-z [doi]
PST - ppublish
SO  - J Med Ultrason (2001). 2006 Dec;33(4):217-24. doi: 10.1007/s10396-006-0113-z. 
      Epub 2006 Dec 22.