PMID- 27281099
OWN - NLM
STAT- MEDLINE
DCOM- 20170202
LR  - 20210109
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 95
IP  - 23
DP  - 2016 Jun
TI  - Benign incidental findings of osteopoikilosis on Tc-99m MDP bone SPECT/CT: A case 
      report and literature review.
PG  - e3868
LID - 10.1097/MD.0000000000003868 [doi]
LID - e3868
AB  - Osteopoikilosis is a benign but rare condition characterized by bone islands 
      throughout the osseous tissue, which could be easily confused with bone 
      metastasis. We present a case of a 37-year-old man presented to orthopedic 
      outpatient clinic with right hip pain for 2 weeks. There were multiple, small 
      punctate lesions scattered throughout the skeleton on radiograph. Subsequent 
      Tc-99m methylene diphosphonate (MDP) bone scan with pelvic single-photon emission 
      computed tomography (SPECT)/computed tomography (CT) showed multiple enostoses 
      without abnormal focal MDP uptake. Therefore, clinical diagnosis was compatible 
      with osteopoikilosis while bone metastasis was unlikely. The symptoms then 
      improved by conservative treatments. Osteopoikilosis is usually an incidental 
      finding on radiograph or CT, and a normal MDP confirmed the diagnosis by 
      excluding bone metastasis. It is important for clinicians to recognize the 
      specific image features to prevent further unnecessary interventions. In 
      addition, bone SPECT/CT could also make the diagnosis in one step.
FAU - Tsai, Szu-Ying
AU  - Tsai SY
AD  - Department of Nuclear Medicine, Far Eastern Memorial Hospital, New Taipei City 
      Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming 
      University National Yang-Ming University School of Medicine Department of Nuclear 
      Medicine, National Taiwan University Hospital and National Taiwan University 
      College of Medicine, Taipei, Taiwan.
FAU - Wang, Shan-Ying
AU  - Wang SY
FAU - Shiau, Yu-Chien
AU  - Shiau YC
FAU - Wu, Yen-Wen
AU  - Wu YW
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (Radiopharmaceuticals)
RN  - X89XV46R07 (Technetium Tc 99m Medronate)
SB  - IM
EIN - Medicine (Baltimore). 2016 Jul 18;95(28):e0916. PMID: 31265603
MH  - Adult
MH  - Diagnosis, Differential
MH  - Humans
MH  - *Incidental Findings
MH  - Male
MH  - Osteopoikilosis/*diagnosis
MH  - Pelvic Bones/*diagnostic imaging
MH  - Radiopharmaceuticals/pharmacology
MH  - Single Photon Emission Computed Tomography Computed Tomography/*methods
MH  - Technetium Tc 99m Medronate/*pharmacology
PMC - PMC4907677
COIS- The authors have no funding and conflicts of interest to disclose.
EDAT- 2016/06/10 06:00
MHDA- 2017/02/06 06:00
PMCR- 2016/06/10
CRDT- 2016/06/10 06:00
PHST- 2016/06/10 06:00 [entrez]
PHST- 2016/06/10 06:00 [pubmed]
PHST- 2017/02/06 06:00 [medline]
PHST- 2016/06/10 00:00 [pmc-release]
AID - 00005792-201606070-00036 [pii]
AID - 10.1097/MD.0000000000003868 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2016 Jun;95(23):e3868. doi: 10.1097/MD.0000000000003868.