PMID- 27282001 OWN - NLM STAT- MEDLINE DCOM- 20160725 LR - 20191113 IS - 1733-1331 (Print) IS - 1733-1331 (Linking) VI - 65 IP - 1 DP - 2016 TI - Antimicrobial Activity of Penicillin G and N-acetylcystein on Planktonic and Sessile Cells of Streptococcus suis. PG - 105-9 AB - The aim of this study was to investigate the capacity of Streptococcus suis strains to form biofilms and to evaluate the antimicrobial activity of Penicillin G and N-acetylcystein (NAC) on both S. suis sessile and planktonic forms. Only non-typeable isolates of S. suis were correlated with a greater biofilm formation capacity. The MCI of Penicillin G and NAC required for inhibiting biofilm growth were higher than the required concentration for inhibiting planktonic growth. The combinations of NAC and Penicillin G showed a strong synergistic activity that inhibited biofilm formation and disrupted the pre-formed biofilm of S. suis. FAU - Espinosa, Ivette AU - Espinosa I FAU - Baez, Michel AU - Baez M FAU - Lobo, Evelyn AU - Lobo E FAU - Martinez, Siomara AU - Martinez S FAU - Gottschalk, Marcelo AU - Gottschalk M LA - eng PT - Journal Article PL - Poland TA - Pol J Microbiol JT - Polish journal of microbiology JID - 101229003 RN - 0 (Anti-Bacterial Agents) RN - Q42T66VG0C (Penicillin G) RN - WYQ7N0BPYC (Acetylcysteine) SB - IM MH - Acetylcysteine/*pharmacology MH - Anti-Bacterial Agents/*pharmacology MH - Biofilms/*drug effects/growth & development MH - Penicillin G/*pharmacology MH - Streptococcus suis/*drug effects/*physiology EDAT- 2016/06/11 06:00 MHDA- 2016/07/28 06:00 CRDT- 2016/06/11 06:00 PHST- 2016/06/11 06:00 [entrez] PHST- 2016/06/11 06:00 [pubmed] PHST- 2016/07/28 06:00 [medline] AID - 10.5604/17331331.1197282 [doi] PST - ppublish SO - Pol J Microbiol. 2016;65(1):105-9. doi: 10.5604/17331331.1197282.