PMID- 27283388 OWN - NLM STAT- MEDLINE DCOM- 20180202 LR - 20180202 IS - 1748-295X (Electronic) IS - 1748-2941 (Linking) VI - 17 IP - 4 DP - 2015 Dec TI - A local network for extracorporeal membrane oxygenation in refractory cardiogenic shock. PG - 49-54 AB - BACKGROUND: Veno-arterial extracorporeal membrane oxygenation (VA ECMO) represents a therapeutic option in patients with refractory cardiogenic shock (RCS). This strategy is limited to a restricted number of centres with capabilities for implanting VA ECMO and management patients on this support. We report on the initial experience of our ECMO referral centre for patients with RCS. METHODS: We retrospectively analysed our ECMO data registry for RCS of 14 patients treated with VA ECMO, consecutively admitted to our intensive cardiac care unit (ICCU), which is an ECMO referral centre. RESULTS: Six patients (6/14, 42%) came from peripheral centres, four were transferred to our ICCU directly. During ICCU stay, four patients died (28.5%) due to multi-organ failure, seven showed a complete recovery while one underwent cardiac transplantation. The remaining two patients died while waiting for cardiac transplantation because of cerebral haemorrhage. The 30-day overall mortality rate was 42.8%, all survivors showed a good neurologic outcome. CONCLUSIONS: In our series, the survival rate of RCS patients supported by VA ECMO is high (57%) and the transfer of RCS patients is feasible and safe. Our data support that a network for RCS is needed to transfer patients in well experienced centres even on ECMO support. FAU - Dini, Carlotta Sorini AU - Dini CS AD - a Intensive Cardiac Care Unit, Azienda Ospedaliero-Universitaria Careggi , Florence , Italy. FAU - Lazzeri, Chiara AU - Lazzeri C AD - a Intensive Cardiac Care Unit, Azienda Ospedaliero-Universitaria Careggi , Florence , Italy. FAU - Chiostri, Marco AU - Chiostri M AD - a Intensive Cardiac Care Unit, Azienda Ospedaliero-Universitaria Careggi , Florence , Italy. FAU - Gensini, Gian Franco AU - Gensini GF AD - a Intensive Cardiac Care Unit, Azienda Ospedaliero-Universitaria Careggi , Florence , Italy. FAU - Valente, Serafina AU - Valente S AD - a Intensive Cardiac Care Unit, Azienda Ospedaliero-Universitaria Careggi , Florence , Italy. LA - eng PT - Journal Article DEP - 20160609 PL - England TA - Acute Card Care JT - Acute cardiac care JID - 101276603 SB - IM MH - Adult MH - Aged MH - Extracorporeal Membrane Oxygenation/*methods MH - Female MH - Follow-Up Studies MH - Hospital Mortality/trends MH - Humans MH - Intensive Care Units MH - Italy/epidemiology MH - Male MH - Middle Aged MH - *Registries MH - Retrospective Studies MH - Shock, Cardiogenic/mortality/*therapy MH - Survival Rate/trends MH - Treatment Outcome OTO - NOTNLM OT - Refractory cardiogenic shock OT - extra-corporeal membrane oxygenation OT - network OT - prognosis EDAT- 2016/06/11 06:00 MHDA- 2016/06/11 06:01 CRDT- 2016/06/11 06:00 PHST- 2016/06/11 06:00 [pubmed] PHST- 2016/06/11 06:01 [medline] PHST- 2016/06/11 06:00 [entrez] AID - 10.3109/17482941.2016.1174272 [doi] PST - ppublish SO - Acute Card Care. 2015 Dec;17(4):49-54. doi: 10.3109/17482941.2016.1174272. Epub 2016 Jun 9.