PMID- 27292168
OWN - NLM
STAT- MEDLINE
DCOM- 20170119
LR  - 20181202
IS  - 1865-1682 (Electronic)
IS  - 1865-1674 (Linking)
VI  - 63
IP  - 5
DP  - 2016 Oct
TI  - Outbreak Investigation of NADC30-Like PRRSV in South-East China.
PG  - 474-9
LID - 10.1111/tbed.12530 [doi]
AB  - Epidemiological outbreak investigations were conducted on NADC30-like porcine 
      reproductive and respiratory syndrome virus (PRRSV) to investigate the prevalence 
      of the disease in south-east China in 2015. Two more provinces were found to have 
      NADC30-like PRRSV circulating besides previously reported six provinces. 
      Phylogenetic analysis showed that these virus isolates were clustered in an 
      independent branch and shared high nucleotide similarity to NADC30, a type 2 
      PRRSV that has been isolated in Unite States in 2008. One NADC30-like PRRSV 
      strain from Henan province was successfully isolated on porcine alveolar 
      macrophages and was tested on 6-week-old specific pathogen-free pigs for 
      pathogenic study. The virus-inoculated pigs showed typical PRRSV clinical 
      symptoms, but all pigs survived throughout the study with a period of 14 days. At 
      necropsy, the lungs of infected pigs developed PRRSV-specific interstitial 
      pneumonia, and virus antigen was detected in lung samples. Therefore, our results 
      indicated NADC30-like PRRSV has widely spread in China and could cause clinical 
      disease on pigs.
CI  - (c) 2016 Blackwell Verlag GmbH.
FAU - Li, C
AU  - Li C
AD  - National Research Center for Veterinary Medicine, Luoyang, China.
FAU - Zhuang, J
AU  - Zhuang J
AD  - National Research Center for Veterinary Medicine, Luoyang, China.
FAU - Wang, J
AU  - Wang J
AD  - National Research Center for Veterinary Medicine, Luoyang, China.
FAU - Han, L
AU  - Han L
AD  - National Research Center for Veterinary Medicine, Luoyang, China.
FAU - Sun, Z
AU  - Sun Z
AD  - National Research Center for Veterinary Medicine, Luoyang, China.
FAU - Xiao, Y
AU  - Xiao Y
AD  - National Research Center for Veterinary Medicine, Luoyang, China.
FAU - Ji, G
AU  - Ji G
AD  - National Research Center for Veterinary Medicine, Luoyang, China.
FAU - Li, Y
AU  - Li Y
AD  - National Research Center for Veterinary Medicine, Luoyang, China.
FAU - Tan, F
AU  - Tan F
AD  - National Research Center for Veterinary Medicine, Luoyang, China.
FAU - Li, X
AU  - Li X
AD  - National Research Center for Veterinary Medicine, Luoyang, China.
FAU - Tian, K
AU  - Tian K
AD  - National Research Center for Veterinary Medicine, Luoyang, China.
AD  - College of Animal Science and Veterinary Medicine, Henan Agricultural University, 
      Zhengzhou, China.
AD  - OIE Porcine Reproductive and Respiratory Syndrome Reference Laboratory, Beijing, 
      China.
LA  - eng
SI  - GENBANK/AF331831
SI  - GENBANK/AY032626
SI  - GENBANK/EF112445
SI  - GENBANK/EF635006
SI  - GENBANK/JN654459
SI  - GENBANK/KF611905
SI  - GENBANK/KJ143621
SI  - GENBANK/KR706343
SI  - GENBANK/KT945017
SI  - GENBANK/U87392
PT  - Journal Article
DEP - 20160613
PL  - Germany
TA  - Transbound Emerg Dis
JT  - Transboundary and emerging diseases
JID - 101319538
RN  - 0 (Antigens, Viral)
SB  - IM
MH  - Animals
MH  - Antigens, Viral/metabolism
MH  - China
MH  - *Disease Outbreaks
MH  - Lung/metabolism/pathology
MH  - Lung Diseases, Interstitial/pathology/virology
MH  - Phylogeny
MH  - Porcine Reproductive and Respiratory Syndrome/*epidemiology
MH  - *Porcine respiratory and reproductive syndrome virus/genetics/immunology
MH  - Swine
OTO - NOTNLM
OT  - HNjz15
OT  - NADC30
OT  - epidemiology
OT  - pathogenesis
OT  - porcine reproductive and respiratory syndrome virus
EDAT- 2016/06/14 06:00
MHDA- 2017/01/20 06:00
CRDT- 2016/06/14 06:00
PHST- 2016/03/03 00:00 [received]
PHST- 2016/06/14 06:00 [entrez]
PHST- 2016/06/14 06:00 [pubmed]
PHST- 2017/01/20 06:00 [medline]
AID - 10.1111/tbed.12530 [doi]
PST - ppublish
SO  - Transbound Emerg Dis. 2016 Oct;63(5):474-9. doi: 10.1111/tbed.12530. Epub 2016 
      Jun 13.